A5041388189- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular anomalies and interventions
- Maternal and fetal healthcare
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Tracheal and airway disorders
- Cardiac electrophysiology and arrhythmias
- Cardiovascular and Diving-Related Complications
- Connective tissue disorders research
- Cardiomyopathy and Myosin Studies
- Healthcare Policy and Management
- Cardiovascular Conditions and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cardiovascular Effects of Exercise
- Nursing Roles and Practices
Houston Methodist
2020-2025
Methodist Hospital
2021-2025
Boston Children's Hospital
2018-2024
Brigham and Women's Hospital
2018-2024
Harvard University
2018-2024
Methodist Hospital
2021-2024
Vale (Brazil)
2013-2022
Florida College
2014-2017
University of Florida
2016-2017
Cleveland Clinic
2012-2014
Background: Patients with diabetes mellitus (DM) are at increased risk of atherothrombotic events, underscoring the importance effective platelet inhibiting therapies. Prasugrel and ticagrelor reduce thrombotic complications to a greater extent than clopidogrel. Subgroup analyses pivotal clinical trials testing prasugrel versus clopidogrel showed DM patients have benefits that were consistent overall trial populations, although magnitude ischemic reduction appeared be enhanced prasugrel....
Background In adults with acquired heart disease, depression is common and associated adverse outcomes. Depression may also be important in congenital disease (CHD). Methods Results We conducted a cohort study of outpatients CHD, aged ≥18 years, enrolled prospective biobank between 2012 2017. Clinical data were extracted from medical records. Survival analysis assessed the relationship depression, defined by history clinical diagnosis major all-cause mortality composite outcome death or...
Aortic stenosis (AS) leads to a reduced effective orifice of the aortic valve, and severity is based on obstructions in flow velocity. In some patients, coexisting structural cardiac abnormalities that increase left ventricular volume, such as patent ductus arteriosus (PDA), may complicate evaluation management. We present case patient with severe AS unrepaired PDA discuss hemodynamic implications important physiological changes resulting from interactions between these lesions. It for...
The incidence of pregnancy in women with cardiovascular disease (CVD) has increased, yet little is known about placental pathology these women. objectives this study were to describe pregnancies complicated by maternal CVD and compare findings among categories CVD. A retrospective, single-center was conducted. Pathology reports for 264 placentas from reviewed prespecified pathologic which then compared against characteristics. Placentas associated congenital heart (n = 171), arrhythmia 43),...
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, management of TAD in pregnancy. Preconception counseling is vital considering hereditary nature potential pregnancy-related complications. Genetic testing imaging surveillance aid assessment. Medical management, including beta-blockade strict...
Objective Guidelines do not exist to determine timing of delivery for women with cardiovascular disease (CVD) in pregnancy. The neonatal benefit a term as compared an early is well described. We sought examine maternal outcomes CVD who delivered the period (370/7 through 386/7 weeks) those later. Study Design This prospective cohort study examining cardiac and obstetric delivering between September 2011 December 2016. associations gestational age at maternal, fetal, characteristics were...
Increasing numbers of women with congenital heart disease are undergoing pregnancy after transcatheter pulmonary valve replacement (TPVR). We present the course 9 pregnancies in 7 TPVR, noting pre-pregnancy, antepartum, and postpartum gradients, as well maternal cardiac, obstetric, neonatal outcomes. (Level Difficulty: Intermediate.)
Four patients with pulmonary valve (PV) disease and patent foramen ovale (PFO) presented dyspnea on exertion. Work-up revealed hypoxemia secondary to right-to-left intracardiac shunt. We demonstrate that correction of the primary culprit right heart overload lesion via PV replacement enabled safe PFO repair resolution hypoxemia.