A5100630167- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Orthoptera Research and Taxonomy
- Identification and Quantification in Food
- Plant and animal studies
- Aquaculture disease management and microbiota
- Chromosomal and Genetic Variations
- Insect symbiosis and bacterial influences
- Plant and Fungal Species Descriptions
- Insect Resistance and Genetics
- Vibrio bacteria research studies
- Bacterial Genetics and Biotechnology
- Mosquito-borne diseases and control
- Gut microbiota and health
- Circular RNAs in diseases
- Insect Utilization and Effects
- Bacterial Identification and Susceptibility Testing
- Biochemical and Molecular Research
- Subterranean biodiversity and taxonomy
- Plant biochemistry and biosynthesis
- Ferroptosis and cancer prognosis
- Biomarkers in Disease Mechanisms
- Cleft Lip and Palate Research
- Histone Deacetylase Inhibitors Research
- Vector-borne infectious diseases
Xi'an Medical University
2021-2025
Shanxi Medical University
2025
Yunnan University of Traditional Chinese Medicine
2025
Anhui University of Traditional Chinese Medicine
2024
Shaanxi Normal University
2016-2023
Zunyi Medical University
2023
Sun Yat-sen University
2023
University of Southern California
2022
Hunan Normal University
2020-2022
Qingdao University
2020
This paper provides the first description of a female Shoveliteratura triangula Shi, Bian & Change, 2011, as well complete mitogenome sequence using next-generation sequencing (NGS) technology. The length entire was 16,152 bp and contained typical gene arrangement, base composition, codon usage found in other related species. overall composition exhibited clear anti-G (10.8%) AT bias (70.5%). third positions all protein-coding genes (PCGs) displayed high AT-content values (81.4%)...
Weaning is stressful for piglets involving nutritional, physiological, and psychological challenges, leading to an increase in the secretion of cortisol, changes gut microbiome metabolites, whereas underlying relationships remain unclear. To elucidate this, 14 Meishan female were divided into weaning group suckling at age 21 days paired by litter body weight. After 48 h experiment, weaned had lower weight, but higher salivary cortisol level than that their mates (P < 0.05). The composition...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolves rapidly under the pressure of host immunity, as evidenced by waves emerging variants despite effective vaccinations, highlighting need for complementing antivirals. We report that targeting a pyrimidine synthesis enzyme restores inflammatory response and depletes nucleotide pool to impede SARS-CoV-2 infection. deploys Nsp9 activate carbamoyl-phosphate synthetase, aspartate transcarbamoylase, dihydroorotase (CAD) catalyzes...
Abstract The strong suppression of Aedes albopictus on two Guangzhou islands in China has been successfully achieved by releasing males with an artificial triple- Wolbachia infection. However, it requires the use radiation to sterilize residual females prevent population replacement. To develop a highly effective tool for dengue control, we tested standalone incompatible insect technique (IIT) control A. urban area Changsha, inland city where recently emerged. Male mosquitoes were produced...
Genomic size variation has long been a focus for biologists. However, due to the lack of genome data, mechanisms behind this and biological significance insect are rarely studied systematically. The detailed taxonomy phylogeny Ensifera, as well extensive documentation concerning their morphological, ecological, behavioral, distributional characteristics, make them strong model studying important scientific problem variation. data on Ensifera rather sparse. In our study, we used flow...
Background High-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) is a key link between several medical conditions and becoming major health concern affecting thousands of people globally. Andrographolide, an active ingredient extracted from Andrographis paniculate, has shown anti-inflammatory anti-fibrosis effects in recent studies. Objective This study aims to explore whether andrographolide can mitigate HFD-induced NAFLD the underlying mechanism. Methods We treated C57B/6...
Lung cancer remains a major global health issue, with non-small cell lung (NSCLC) constituting approximately 85% of cases. Ferritinophagy, pivotal autophagic process in ferroptosis, plays an essential role tumor initiation and progression. However, the specific contributions ferritinophagy-related genes (FRGs) to NSCLC pathogenesis remain incompletely understood. In this study, weighted gene co-expression network analysis (WGCNA) was employed identify key modular associated FRG scores. Genes...
The relict gull (Larus relictus, Charadriiformes, Laridae) classified as vulnerable in the IUCN Red List is defined a first-class national protected bird China. However, our knowledge of evolutionary history L. relictus limited. Here, we performed whole-genome resequencing (n = 14) and brunnicephalus 3) to explore genetic relationships population structures understand their adaptive evolution. whole genome generated 667.55 Gb clean reads with an average sequencing depth ~ 29×. genomic...
Vibrio alginolyticus is one of the most abundant microorganisms in marine environments and also an opportunistic pathogen mediating high-mortality vibriosis animals. Alternative sigma factors play essential roles bacterial pathogens adaptation to environmental changes during infection various niches, but little known about them for V. Our previous investigation indicated that transcript level gene rpoX significantly decreased RpoE mutant. Here, we found was highly expressed response high...
The Tibetan Partridge (Perdix hodgsoniae) is an endemic species distributed in high-altitude areas of 3600-5600 m on the Qinghai-Tibet Plateau. To explore how adapted to high elevation environment, we assembled a draft genome based both Illumina and PacBio sequencing platforms with its population genetics genomics analysis. In total, 134.74 Gb short reads 30.81 long raw data were generated. 1.05-Gb had contig N50 4.56 Mb, 91.94% complete BUSCOs. 17 457 genes annotated, 11.35% was composed...
Metabolic reprogramming is a crucial hallmark of tumorigenesis. Modulating the reprogrammed energy metabolism an attractive anticancer therapeutic strategy. We previously found natural product, bouchardatine, modulated aerobic and inhibited proliferation in colorectal cancer cell (CRC). Herein, we designed synthesized new series bouchardatine derivatives to discover more potential modulators. applied dual-parametric high-content screening (HCS) evaluate their AMP-activated protein kinase...
Abstract Background The sophisticated insect olfactory system plays an important role in recognizing external odors and enabling insects to adapt environment. Foraging, host seeking, mating, ovipositing other forms of chemical communication are based on olfaction, which requires the participation multiple genes. exclusive evolutionary trend Orthoptera is excellent model for studying evolution, but limited olfaction research available these species. olfactory-related genes Ceracris...
Abstract Background The relict gull ( Larus relictus ), was classified as vulnerable on the IUCN Red List and is a first-class national protected bird in China. Genomic resources for L. are lacking, which limits study of its evolution conservation. Results In this study, based Illumina PacBio sequencing platforms, we successfully assembled genome , one few known reference genomes genus . size final 1.21 Gb, with contig N50 8.11 Mb. A total 18,454 genes were predicted from assembly results,...
The grasshopper Shirakiacris shirakii is an important agricultural pest and feeds mainly on gramineous plants, thereby causing economic damage to a wide range of crops. However, genomic information this species extremely limited thus far, transcriptome data relevant insecticide resistance control are also not available.The S. was sequenced using the Illumina HiSeq platform, we de novo assembled transcriptome.Its sequencing produced total 105,408,878 clean reads, assembly revealed 74,657...
Le Fort III osteotomy was usually applied to correct midface hypoplasia in Apert syndrome, and various surgical modifications have been developed recent years. In this article, we reported the simultaneous I, II, osteotomies for segmental advancement of deficiency involving nasal bones, zygoma, inferior orbital rims, maxilla an adult Chinese patient with syndrome. To achieve ideal different parts simultaneously, divided into 4 segments, including bone combined upper portion maxilla, lower...
It is widely accepted that repetitive elements (REs) represent the primary mechanism driving genome size variation across eukaryotes. The observed sizes and REs of 59 species within Acrididae were obtained characterized. ranged from 6.60 pg to 19.35 pg, while proportion varied 57.92 % 83.58 %. contributors identified as LTR (2.34 ~ 20.98 %) LINEs (6.70 16.33 %). results ancestral reconstruction indicated in nodes was 69.53 %, which suggests they have undergone extensive expansion or...
Gelochelidon nilotica and Sterna hirundo are two sympatric breeding species. The mitogenomes of G. S. 16,748 bp 16,707 in size. Both reveal the same gene order genomic organization to that typical avian mtDNA. first conserved blocks with a interrupted poly-C present species control regions, but not existed albifrons. Seventeen 11 simple sequence repeats found hirundo, respectively. Phylogenetic analysis indicated Sternidae has closest relationship Laridae. We supported Stercorariidea is...
Most orthopteran insects are phytophagous and some important pests in agriculture forests. Many intestinal microflora of Orthoptera have been reported, primarily from Acridoidea there few reports other taxa. In this study, we collected 15 individuals representing five species ( Ruspolia lineosa , Tetrix japonica Erianthus versicolor Gryllotalpa orientalis Teleogryllus emma ) belonging to superfamilies (Tettigonioidea, Tetrigoidea, Eumastacoidea, Gryllotalpoidea Grylloidea) characterise...
Xizicus Gorochov, 1993, the quiet-calling katydid, is a diverse genus with 68 species in world, which includes more than 45 China, has undergone numerous taxonomic revisions contradicting conclusions. In this study complete mitochondrial genome of (Haploxizicus) maculatus collected from Hainan for first time was sequenced using Next-Generation Sequencing (NGS) technology. The length whole mitogenome 16,358 bp and contains typical gene arrangement, base composition, codon usage found other...
The objective of this study is to explore the common genetic and epigenetic mechanism ulcerative colitis (UC) sporadic colorectal cancer (SCRC) by observing genes methylation level single nucleotide polymorphisms (SNPs) different disease courses in UC SCRC.Two hundred subjects were enrolled, including 40 healthy control (HC) group, 50 short course group (SUC), 52 long (LUC), 58 SCRC group. Methylation-specific polymerase chain reaction was used detect MINT1 cyclooxygenase 2 (COX-2) gene....
Abstract Acrididae are diverse in size, body shape, behavior, ecology and life history; widely distributed; easy to collect; important agriculture. They represent promising model candidates for functional genomics, but their extremely large genomes have hindered this research; establishing a reference transcriptome species is the primary means of obtaining genetic information. Here, two species, Gomphocerus licenti Mongolotettix japonicus , were selected full-length (FL) PacBio sequencing....
Objective: To investigate the correlation of expression platelet microRNA-223 (miR-223) with degree activation and severity coronary lesions in patients artery disease (CAD). Methods: A total 204 consecutive underwent angiography (CAG) at Beijing Anzhen Hospital between April December 2016 were enrolled. According to CAG results, all divided into two groups: 112 CAD group 92 control group. Real-time fluorescent quantitative PCR was used detect level miR-223 mRNA its target gene P2Y12. Flow...