A5028473860- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Carcinogens and Genotoxicity Assessment
- Pesticide Residue Analysis and Safety
- Agricultural safety and regulations
- Per- and polyfluoroalkyl substances research
- Air Quality and Health Impacts
- Nutritional Studies and Diet
- Mercury impact and mitigation studies
- Genetic and phenotypic traits in livestock
- Mycotoxins in Agriculture and Food
- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Microplastics and Plastic Pollution
- Pharmacological Effects and Assays
- Colorectal Cancer Screening and Detection
- Isotope Analysis in Ecology
- Meat and Animal Product Quality
- Antibiotics Pharmacokinetics and Efficacy
- Coccidia and coccidiosis research
- Analytical Chemistry and Chromatography
- Gastric Cancer Management and Outcomes
- Analytical chemistry methods development
- Food Safety and Hygiene
- Biblical Studies and Interpretation
University of Manchester
2018-2024
Fera Science (United Kingdom)
2012-2023
Food and Agriculture Organization of the United Nations
2020-2021
Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation und Technologie
2021
Czech Academy of Sciences, Institute of Biotechnology
2018
Environmental Research Institute
1997-2017
University of Auckland
2017
Nutreco (Canada)
2012
Emily Carr University of Art and Design
2011
Food Standards Agency
2005-2010
The European Commission asked EFSA for a scientific evaluation on the risks to human health related presence of perfluoroalkyl substances (PFASs) in food. Based several similar effects animals, toxicokinetics and observed concentrations blood, CONTAM Panel decided perform assessment sum four PFASs: PFOA, PFNA, PFHxS PFOS. These made up half lower bound (LB) exposure those PFASs with available occurrence data, remaining contribution being primarily from short half-lives. Equal potencies were...
The European Commission asked EFSA for a scientific evaluation on the risks to human health related presence of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic (PFOA) in food. Regarding PFOS PFOA occurrence, final data set available dietary exposure assessment contained total 20,019 analytical results (PFOS n = 10,191 9,828). There were large differences between upper lower bound due methods with insufficient sensitivity. CONTAM Panel considered estimates be closer true levels....
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring predominantly in cereal grains. Following the request of European Commission, CONTAM Panel assessed risk to animal and human health related DON, 3-acetyl-DON (3-Ac-DON), 15-acetyl-DON (15-Ac-DON) DON-3-glucoside food feed. A total 27,537, 13,892, 7,270 2,266 analytical data for 3-Ac-DON, 15-Ac-DON DON-3-glucoside, respectively, food, feed unprocessed grains collected from 2007 2014 were used. For exposure,...
Ever since the interest in organic environmental contaminants first emerged 50 years ago, there has been a need to present discussion of such chemicals and their transformation products using simple abbreviations so as avoid repetitive use long chemical names. As number concern increased, also increased dramatically, sometimes resulting different for same chemical. In this article, we propose flame retardants (FRs) substituted with bromine or chlorine atoms including functional group...
The European Commission asked EFSA for a scientific opinion on the risks animal and human health related to presence of dioxins (PCDD/Fs) DL-PCBs in feed food. data from experimental epidemiological studies were reviewed it was decided base risk assessment effects observed humans use as supportive evidence. critical effect semen quality, following pre- postnatal exposure. study showed NOAEL 7.0 pg WHO
In 2011, a joint World Health Organization (WHO) and United Nations Environment Programme (UNEP) expert consultation took place, during which the possible inclusion of brominated analogues dioxin-like compounds in WHO Toxicity Equivalency Factor (TEF) scheme was evaluated. The panel concluded that polybrominated dibenzo-p-dioxins (PBDDs), dibenzofurans (PBDFs), some biphenyls (dl-PBBs) may contribute significantly daily human background exposure to total dioxin toxic equivalencies (TEQs)....
Zearalenone (ZEN), a mycotoxin primarily produced by Fusarium fungi, occurs predominantly in cereal grains.The European Commission asked EFSA for scientific opinion on the risk to animal health related ZEN and its modified forms feed.Modified of occurring feed include phase I metabolites a-zearalenol (a-ZEL), b-zearalenol (b-ZEL), a-zearalanol (a-ZAL), b-zearalanol (b-ZAL), zearalanone (ZAN) II conjugates.ZEN has oestrogenic activity differs considerably.For ZEN, Panel Contaminants Food...
EFSA was asked by the European Commission to deliver a scientific opinion on risks for human health related presence of pyrrolizidine alkaloids (PAs) in honey, tea, herbal infusions and food supplements identify PAs relevance aforementioned commodities other feed food. are large group toxins produced different plant species. In 2011, Panel Contaminants Food Chain (CONTAM Panel) assessed feed. Based occurrence data limited CONTAM concluded that there possible concern those toddlers children...
The European Commission asked EFSA to update its 2011 risk assessment on polybrominated diphenyl ethers (PBDEs) in food, focusing 10 congeners: BDE-28, -47, -49, -99, -100, -138, -153, -154, -183 and ‑209. CONTAM Panel concluded that the neurodevelopmental effects behaviour reproductive/developmental are critical rodent studies. For four congeners (BDE-47, -209) derived Reference Points, i.e. benchmark doses corresponding lower 95% confidence limits (BMDLs), for endpoint-specific responses....
Concentrations of 24 elements including metals in the 2006 UK Total Diet Study (TDS) were measured and dietary exposures estimated. Composite samples for 20 TDS food groups (bread, fish, fruit, etc.) collected from towns analysed their levels aluminium, antimony, arsenic, barium, bismuth, cadmium, chromium, copper, germanium, indium, lead, manganese, mercury, molybdenum, nickel, palladium, platinum, rhodium, ruthenium, selenium, strontium, thallium, tin, zinc. each lower than or similar to...
There is increasing concern over the toxicity and environmental distribution of a number classes brominated compounds such as polybrominated diphenyl ethers (PBDEs), biphenyls (PBBs) used flame retardants well mixed bromochloro dibenzo-p-dioxins dibenzofurans (PBDD/Fs PBrClDD/Fs). Observed ubiquity bio-accumulative characteristics coupled with dioxin-like have led to some these being classified POPs. Unlike chlorinated dioxins levels in environment shows an trend. The main pathway observed...
Tetrodotoxin (TTX) and its analogues are produced by marine bacteria have been detected in bivalves gastropods from European waters. The Commission asked EFSA for a scientific opinion on the risks to public health related presence of TTX gastropods. Panel Contaminants Food Chain reviewed available literature but did not find support minimum lethal dose humans 2 mg, mentioned various reviews. Some human case reports describe serious effects at 0.2 corresponding 4 μg/kg body weight (bw)....
The most commonly consumed shellfish species produced in Scotland - mussels, oysters and scallops were investigated for the occurrence of a range brominated chlorinated contaminants order to establish current levels estimate human dietary exposure. Flesh from individual sub-samples was representatively pooled 35 composites analysed dioxins (PBDD/Fs, PCDD/Fs), biphenyls (PBBs, PCBs), polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs) tetrabromobisphenol A (TBBPA)....
The CONTAM Panel updated the assessment of risks for human health related to presence 3-monochloropropane diol (3-MCPD) and its fatty acid esters in food published 2016 view scientific divergence identified establishment tolerable daily intake (TDI) Joint FAO/WHO Expert Committee on Food Additives Contaminants (FAO/WHO) report 2017.In this update, dose-response analysis was performed following recent EFSA Scientific guidance use benchmark dose (BMD) approach risk assessment, a review...
The EFSA Panel on Contaminants in the Food Chain (CONTAM) established a tolerable daily intake (TDI) for fumonisin B
Fumonisins, mycotoxins primarily produced by Fusarium verticillioides and proliferatum, occur predominantly in cereal grains, especially maize. The European Commission asked EFSA for a scientific opinion on the risk to animal health related fumonisins their modified hidden forms feed. Fumonisin B1 (FB 1), FB 2 3 are most common of feedstuffs thus were included assessment. 1, have same mode action considered as having similar toxicological profile potencies. For fumonisins, Panel Contaminants...
The European Commission asked EFSA for a scientific opinion on the risks animal and human health related to presence of chlorinated paraffins in feed food. data experimental animals were reviewed CONTAM Panel identified liver, kidney thyroid as target organs SCCP MCCP mixtures tested repeated dose toxicity studies. Decreased pup survival subcutaneous haematoma/haemorrhage also critical effects an mixture. For LCCP tested, liver was organ. selected reference points BMDL 10 2.3 mg/kg bw per...