A5033821656- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Indoor Air Quality and Microbial Exposure
- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Metabolism and Genetic Disorders
- Diabetes and associated disorders
- Respiratory and Cough-Related Research
- Neurogenetic and Muscular Disorders Research
- Inflammatory Myopathies and Dermatomyositis
- Respiratory viral infections research
- Insects and Parasite Interactions
- Adrenal Hormones and Disorders
- Pediatric health and respiratory diseases
- Biomedical Research and Pathophysiology
- Pharmacological Effects and Toxicity Studies
- Systemic Sclerosis and Related Diseases
- Botulinum Toxin and Related Neurological Disorders
- Autoimmune and Inflammatory Disorders
- Noise Effects and Management
- Soft tissue tumor case studies
- Biochemical and Molecular Research
- Glycogen Storage Diseases and Myoclonus
Rho (United States)
2011-2024
RTI International
2020
National Institute of Environmental Health Sciences
2002-2018
National Institutes of Health
2003-2018
Triangle
2005-2009
Otto Wagner Hospital
2006
University of Iowa
2005
United States Department of Housing and Urban Development
2004
Harvard University
2004
Research Triangle Park Foundation
1981-2003
Although research has shown that early life exposure to household endotoxin protects against development of allergies, studies are less clear on the relationship between and prevalence wheezing asthma. We assayed 2,552 house dust samples in a representative nationwide sam- ple explore relationships exposures risk factors for asthma, asthma symptoms, medication use.House was vacuum-sampled from five locations within homes endotoxin. Health, demographic, housing information assessed through...
Coronary heart disease is responsible for one of every five deaths in the United States. Recent epidemiological studies have shown an association between periodontal and coronary disease. The purpose this cross-sectional study was to verify using data from third National Health Nutrition Examination Survey (NHANES III). Data 5564 people 40 years age older who had complete assessments information on attack were evaluated. outcome self-reported history (yes vs. no). main independent variable...
OBJECTIVES: Cigarette smoking is a leading risk factor for periodontal disease. This cross-sectional study investigated the relation between environmental tobacco smoke (ETS) and disease in United States. METHODS: Data were obtained from Third National Health Nutrition Examination Survey (1988-1994). The outcome was disease, defined as 1 or more sites with attachment loss of 3 mm greater pocket depth 4 at same site. Exposure to ETS home work self-reported. analyzed 6611 persons 18 years...
BackgroundThe relationship of domestic endotoxin exposure to allergy and asthma has been widely investigated. However, few studies have evaluated predictors household endotoxin, none done so for multiple locations within homes on a national scale.ObjectivesWe assayed 2,552 house dust samples in nationwide study understand the bedroom floors, family room beds, kitchen sofas.MethodsReservoir from five was demographic housing information assessed through questionnaire onsite evaluation 2,456...
The incidence and morbidity of wheezing illnesses childhood asthma is especially high in poor urban areas. This paper describes the study design, methods, population Urban Environment Childhood Asthma (URECA) study, which was established to investigate immunologic causes among inner-city children. URECA an observational prospective that enrolled pregnant women central areas Baltimore, Boston, New York City, St. Louis following their offspring from birth through age 7 years. cohort consists...
Stimuli such as inflammation or hypoxia induce cytochrome P450 epoxygenase-mediated production of arachidonic acid-derived epoxyeicosatrienoic acids (EETs). EETs have cardioprotective, vasodilatory, angiogenic, anti-inflammatory, and analgesic effects, which are diminished by EET hydrolysis yielding biologically less active dihydroxyeicosatrienoic (DHETs). Previous in vitro assays suggested that epoxide hydrolase 2 (EPHX2) is responsible for nearly all hydrolysis. EPHX1, exhibits slow vitro,...
We characterized the prevalence of cockroach allergen exposure in a nationally representative sample U.S. homes and assessed risk factors for elevated concentrations.We used data from National Survey Lead Allergens Housing, population-based cross-sectional survey.Participants were residents 831 survey.We analyzed allergen, questionnaire, observational homes.Cockroach (Bla g 1) concentrations exceed 2.0 U/g, level associated with allergic sensitization, 11% living room floors 13% kitchen...
The 2017 Addendum Guidelines for the Prevention of Peanut Allergy in United States recommend that pediatricians assess infant peanut allergy risk and introduce diet at age 4 to 6 months. Early introduction has potential prevent development.
Propranolol is a nonselective beta-adrenergic receptor antagonist. A multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 2b trial enrolled participants aged 18 to 65 years with temporomandibular disorder myalgia evaluate efficacy and safety of propranolol compared placebo in reducing facial pain. Participants were randomized 1:1 either extended-release hydrochloride (60 mg, BID) or placebo. The primary endpoint was change pain index (FPI = intensity multiplied by...