A5024467564- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Immunotherapy and Immune Responses
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Urinary Tract Infections Management
- 3D Printing in Biomedical Research
- Neutropenia and Cancer Infections
- Radiation Detection and Scintillator Technologies
- Infection Control in Healthcare
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Immune Response and Inflammation
- Antibiotics Pharmacokinetics and Efficacy
- Atomic and Subatomic Physics Research
- Infection Control and Ventilation
- Cancer Immunotherapy and Biomarkers
- Extracellular vesicles in disease
- Immune cells in cancer
- Seaweed-derived Bioactive Compounds
- Nuclear Physics and Applications
- Infective Endocarditis Diagnosis and Management
Seoul National University
2010-2025
Sejong University
2025
New Generation University College
2020-2025
Seoul National University Hospital
2019-2025
Korea University
2023
University Hospitals Seidman Cancer Center
2023
Case Western Reserve University
2020-2023
Daewoo Pharma (South Korea)
2023
National University College
2023
Seoul National University Bundang Hospital
2021-2022
The most investigated semiconductor photosensor for MRI-compatible PET detectors is the avalanche photodiode (APD). However, silicon photomultiplier (SiPM), also called Geiger-mode APD, gaining attention in development of next generation PET/MRI systems because SiPM has much better performance than APD. We have developed an system based on multichannel arrays to allow simultaneous PET/MRI. <b>Methods:</b> scanner consists 12 detector modules with a ring diameter 13.6 cm and axial extent 3.2...
Complex, three-dimensional (3D) mesostructures that incorporate advanced, mechanically active materials are of broad, growing interest for their potential use in many emerging systems. The technology implications range from precision-sensing microelectromechanical systems, to tissue scaffolds exploit the principles mechanobiology, mechanical energy harvesters support broad bandwidth operation. work presented here introduces strategies guided assembly and heterogeneous integration as routes...
Echinococcosis, caused by the tapeworm Echinococcus, is rare in Korea and primarily imported from endemic areas. We report a case of 37-year-old Korean man with multiple large hepatic cysts, initially diagnosed as simple cysts at local clinic 2018. The patient had lived Oman, an area, for several months 2016. Upon referral to tertiary hospital 2023, due progressive cyst enlargement, liver magnetic resonance imaging revealed three water lily sign. Serum IgG against Echinococcus was positive...
Extracellular vesicles derived during differentiation of stem cells have the potential to induce tissue-specific differentiation.
Drug-based chemotherapy is associated with serious side effects. We developed a chemotherapeutic system comprising chitosan hydrogel (CH-HG) containing gold cluster-labeled liposomal doxorubicin (DOX) (CH-HG-GLDOX) as an injectable drug depot system. CH-HG-GLDOX can be directly injected into tumor tissue without surgical procedure, allowing this to act reservoir for DOX. enhanced the retention time of DOX in and controlled its release response near-infrared (NIR) irradiation, resulting...
Microelectromechanical systems remain an area of significant interest in fundamental and applied research due to their wide ranging applications. Most device designs, however, are largely 2D constrained only a few simple geometries. Achieving tunable resonant frequencies or broad operational bandwidths requires complex components and/or fabrication processes. The work presented here reports unusual classes 3D micromechanical the form vibratory platforms assembled by controlled compressive...
Bone marrow-derived macrophages (BMDMs) are widely used primary cells for studying macrophage function. However, despite numerous protocols that currently available, lack of a notable consensus on generating BMDMs may obscure the reliability in comparing findings from different studies or laboratories. In this study, we addressed effect cell density resulting population. With reference to previously published methods, bone marrow wild type C57BL/6 mice were plated at either 4 × 105 5 106 per...
Cytotoxic CD8+ T cell-based cancer immunotherapy has been extensively studied and applied, however, tumor cells are known to evade immune responses through the expression of checkpoints, such as programmed death ligand 1 (PD-L1). To overcome these issues, antibody-based checkpoint blockades (eg, antiprogrammed cell (anti-PD-1) anti-PD-L1) have revolutionized improve responses. However, their therapeutic efficacy is limited 15%-20% overall objective response rate. Moreover, PD-L1 secreted...
Abstract Background Viridans group streptococci (VGS) persist as the dominant cause of community-acquired native-valve endocarditis, contributing to 20% cases. The incidence streptococcal infective endocarditis (IE) exceeds that Staphylococcus aureus IE, notably in Asia. However, risk factors guide decision conduct echocardiography rule out IE patients with VGS bloodstream infections (BSIs) remain unclear. Therefore, our study aimed identify independent for BSIs. Methods This retrospective...
Abstract Background Despite the rapid deaths due to Acinetobacter baumannii bacteremia, clinical impact of microbiological characteristics A. strains on early mortality (EM) is unclear. We aimed identify associated with EM. Methods Clinical information and isolates from patients bacteremia January 2015 December 2021 were collected. collected patients’ data, including demographic severity, source infection, antibiotic therapy. EM was defined as death within 3 d initial positive blood culture,...
Abstract Background Anti-CD20 therapy has been associated with severe pneumonia in coronavirus disease 2019 (COVID-19) patients. This study aimed to evaluate the impact of anti-CD20 on acute respiratory syndrome 2 (SARS-CoV-2) infection and COVID-19–related outcomes using a nationwide cohort. Methods We used K-CoV-N database, integrating Korea Disease Control Prevention Agency National Health Insurance Service. Adults (≥19 years) diagnosed conditions warranting from January 2020 December...
To date, placental trophoblasts have been of interest in the fields obstetrics and gynecology, mainly due to their involvement formation a connection between mother fetus that aids development fetal survival. However, regenerative capacities for application medicine tissue engineering are poorly understood. Here, we aim determine skin regeneration anti-aging trophoblast-derived conditioned medium (TB-CM) exosomes (TB-Exos) using human normal dermal fibroblasts (HNDFs). TB-CM TB-Exos...
There is an ongoing controversy regarding whether single-occupancy rooms are superior to multiple-occupancy in terms of infection prevention. We investigated treatment a room associated with increased incidence nosocomial coronavirus disease 2019 (COVID-19) compared room.