A5067328203- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Cytokine Signaling Pathways and Interactions
- DNA Repair Mechanisms
- Immune Cell Function and Interaction
- Single-cell and spatial transcriptomics
- BRCA gene mutations in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- RNA modifications and cancer
- MicroRNA in disease regulation
- Genetic factors in colorectal cancer
- Molecular Biology Techniques and Applications
- Nutrition, Genetics, and Disease
- PARP inhibition in cancer therapy
- Neonatal Respiratory Health Research
- Cancer, Lipids, and Metabolism
- Climate Change Communication and Perception
- Bacillus and Francisella bacterial research
- Cancer-related Molecular Pathways
- Nuclear Receptors and Signaling
- COVID-19 and Mental Health
- Environmental Education and Sustainability
- Psychological and Temporal Perspectives Research
- Microbial Inactivation Methods
Vanderbilt University Medical Center
2024
Vanderbilt University
2024
McMaster University
2024
The Francis Crick Institute
2019-2024
Cancer Society of New Zealand
2023
University of Auckland
2023
Australia and New Zealand Banking Group
2022
Ollscoil na Gaillimhe – University of Galway
2019-2020
University Hospitals of North Midlands NHS Trust
2020
The University of Melbourne
2016-2019
BRCA1 -mutated tumors may be particularly vulnerable to dual checkpoint inhibition.
There is a strong biological rationale for the augmentation of allogeneic natural killer (NK) cell therapies with chimeric antigen receptor (CAR) to enhance acute myeloid leukemia (AML) targeting. CD38 an established immunotherapeutic target in multiple myeloma and under investigation as AML. expression on NK cells its further induction during ex vivo expansion represent barriers development CAR-NK therapy. We set out develop therapy AML, first by using line which has low baseline...
This study aimed to estimate the association between anxiety associated with COVID-19 and somatic symptoms, using data from a large, representative sample (N=2025) of UK adult population. Results showed that moderate high levels were significantly general in particular gastrointestinal fatigue symptoms. pattern associations remained significant after controlling for generalised disorder, pre-existing health problems, age, gender income. is first evidence makes unique contribution...
Abstract Recent evidence suggests that Alzheimer’s disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators soluble TREM2 levels such minor allele protective variant (rs1582763) is associated with higher sTREM2 lower AD while (rs6591561) relates to risk. Our group previously found Aβ 40 , worse blood–brain barrier (BBB) integrity (measured CSF/plasma albumin ratio), CSF tau, suggesting strong associations amyloid abundance both BBB...
The benefits of physical activity for mental health and well-being the associations between parental children's have been well established. These important issues tend to be examined separately however, there is limited research on parent child when all considered together. While family focused practice recommended provide support parents who problems their families includes various components (such as psychoeducation, parenting), promoting children not usually a core component these interventions.