A5062097488- Genetic diversity and population structure
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Forensic and Genetic Research
- Drug-Induced Hepatotoxicity and Protection
- Genetic Associations and Epidemiology
- Amphibian and Reptile Biology
- Identification and Quantification in Food
- Liver Disease Diagnosis and Treatment
- Species Distribution and Climate Change
- Insect-Plant Interactions and Control
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Race, Genetics, and Society
- Forensic Anthropology and Bioarchaeology Studies
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Metabolomics and Mass Spectrometry Studies
- Trypanosoma species research and implications
- Genomics and Phylogenetic Studies
- Insect and Arachnid Ecology and Behavior
- Metabolism and Genetic Disorders
- Trace Elements in Health
- Insect Resistance and Genetics
- Insect behavior and control techniques
Universitat de les Illes Balears
2016-2025
Hospital Universitario Quirónsalud Madrid
2023
Research Institute of Health Sciences
2009-2020
Servei de Salut de les Illes Balears
1996-2020
Universidad Nacional de La Plata
2012
University of Copenhagen
2010
Instituto Nacional de Toxicología y Ciencias Forenses
2010
Universitat de València
1986-2009
Hospital Universitario Son Dureta
2004-2008
Spanish Society of Family and Community Medicine
2006
Polymorphic variations in the serotonin transporter gene (5-HTT) moderate depressogenic effects of tryptophan depletion. After childbirth there is a sharp reduction brain availability, thus polymorphic 5-HTT may play similar role post-partum period.To study mood changes after delivery.One thousand, eight hundred and four depression-free Spanish women were studied post-partum. We evaluated depressive symptoms at 2-3 days, 8 weeks 32 used diagnostic interview to confirm major depression for...
Abstract The Balearic lizard, Podarcis lilfordi, is present in 43 insular populations the Cabrera archipelago and around coasts of Mallorca Menorca islands (Spain). We studied lizard densities over entire range distribution, analyzing observed differences density relation to island area, habitat diversity, availability resources, presence predators, competitors human disturbances. varies from less than 35 almost 8000 lizards ha–1, with an average 1500 ha–1. In some very small islets we...
Gut microbial communities provide essential functions to their hosts and are known influence both ecology evolution. However, our knowledge of these complex associations is still very limited in reptiles. Here we report the 16S rRNA gene faecal microbiota profiles two lizard species endemic Balearic archipelago (Podarcis lilfordi P. pityusensis), encompassing allopatric range distribution through a noninvasive sampling, as an alternative previous studies that implied killing specimens IUCN...
The Balearic archipelago (Majorca, Minorca, and Ibiza islands the Chuetas, a small inbred community of descendants Sephardic Jews) Valencia were studied by means sequencing 404-bp segment hypervariable region I (HVRI) mtDNA in 231 individuals. In total, 127 different haplotypes defined 92 variable positions identified. incidence unique was very low, especially Chuetas. A remarkable observation Chueta high frequency (23%) preHV-1, Middle Eastern lineage that is closely related, though not...
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors used to reduce the synthesis pro-inflammatory mediators. In addition, inflammation often leads harmful generation nitric oxide. Efforts being done in discovering safer NSAIDs molecules capable inhibiting lipid mediators oxide side effects associated with long term therapies. Methodology/Principal Findings The analogue arachidonic acid (AA), 2-hydroxy-arachidonic (2OAA), was designed inhibit...
MetaDAG is a web-based tool developed to address challenges posed by big data from omics technologies, particularly in metabolic network reconstruction and analysis. The capable of constructing networks for specific organisms, sets reactions, enzymes, or KEGG Orthology (KO) identifiers. By retrieving the database, helps users visualize analyze complex interactions efficiently. computes two models: reaction graph directed acyclic (m-DAG). represents reactions as nodes metabolite flow between...
An extensive survey of mitochondrial DNA (mtDNA) restriction polymorphism in 156 isofemale lines from 29 different geographic populations Drosophila subobscura distributed throughout the Old World was carried out. Ten enzymes were used, five which revealed site polymorphism. Of 31 sites detected, 13 found to be polymorphic. Comparisons with mtDNA map yakuba indicate that variable are mainly concentrated protein genes, especially those corresponding NADH complex. A total haplotypes observed,...
ABSTRACT Aim To describe and analyse phylogeographical patterns in the endangered endemic lizard Podarcis lilfordi from across its remaining range thereby establish baseline information on genetic diversity that will help determine conservation priorities assist future reintroduction programs. Location Balearic Islands, Spain. Methods We analysed mitochondrial DNA (2382 bp sequence eight genes) 118 individuals characterized relationships among haplotypes using parsimony networks, as well...
The association between polymorphism at the mc1r locus and colour variation was studied in two wall lizard species (Podarcis lilfordi P. pityusensis) from Balearic archipelago. Podarcis comprises several deep mitochondrial lineages, oldest of which originated Pliocene, while much shallower lineages are found pityusensis. Here, we examined whether specific substitutions were associated with melanic colouration islet populations these species. Homologous nuclear sequences covering most gene...
The evolution of Drosophila subobscura mitochondrial DNA has been studied in experimental populations, founded with flies from a natural population Esporles (Majorca, Balearic Islands, Spain). This population, like other European ones, is characterized by the presence two very common (>96%) haplotypes (called I and II) rare endemic that appear at low frequencies. There no statistical evidence positive Darwinian selection acting on variants according to Tajima's neutrality test. Two one...
OBJECTIVE Most previous studies have failed to demonstrate any mutations in the type II 3β hydroxysteroid dehydrogenase (HSD3B2) gene patients satisfying hormonal criteria of nonclassic 3β‐hydroxysteroid deficiency, suggesting that a mutant protein is not cause this disorder. We screened HSD3B2 for girls with premature pubarche and diagnosis deficiency. DESIGN From 30 pubarche, we selected 9 whose ACTH‐stimulated 17‐hydroxypregnenolone levels were elevated (≥6 SD) mutations. MEASUREMENTS All...
BACKGROUND: The analysis of X‐chromosome markers can be valuable in particular situations, for example, deficiency kinship cases, where the putative father cannot typed. short‐tandem repeats (X‐STRs) are widely used forensic genetics, while use single‐nucleotide polymorphisms (X‐SNPs) is still limited. STUDY DESIGN AND METHODS: usefulness a set 25 SNPs located across was analyzed 13 populations. applicability X‐SNPs testing illustrated two immigration cases conclusions based on 15 autosomal...
Abstract Two monophyletic sister species of wall lizards inhabit the two main groups B alearic I slands: P odarcis lilfordi from islets and small islands around M allorca enorca pityusensis biza, F ormentera associated islets. Genetic diversity within endangered . has been well characterized, but not studied in depth. Here, 2430 bp mt DNA 15 microsatellite loci were analysed populations across its natural range. genetic groupings identified, although geographical structuring differed...
Abstract Aims To characterize the genetic and morphological diversification of endangered Balearic lizard Podarcis lilfordi to assess relevance this diversity, how it is described, conservation measures. Location This study covers all populations lizard, , present in its range distribution at coastal islets Menorca, Mallorca Cabrera Archipelago. Methods We analysed variation across 43 known extant using mitochondrial nuclear markers. examined morphometric scalation characters using, some...
Symbiosis between prokaryotes and eukaryotes is a widespread phenomenon that has contributed to the evolution of eukaryotes. In cockroaches, two types symbionts coexist: an endosymbiont in fat body (
Abstract: ‘ Chueta’ was the name given to Catholic descendants of Jewish victims last Spanish Inquisition process in Majorca Island western Mediterranean. We have studied allele distribution HLA‐A, ‐B, ‐Cw, ‐DRB1 and ‐DQB1 loci 103 random, healthy, unrelated individuals belonging ancient Majorcan community, known locally as Chuetas, 589 from Balearic population selected because their typical – Majorca, Minorca or Ibiza lineages according ancestor's place birth. Our aim establish genetic...