A5011029233- Psoriasis: Treatment and Pathogenesis
- Plant Pathogens and Fungal Diseases
- Mycotoxins in Agriculture and Food
- Cytokine Signaling Pathways and Interactions
- Plant-Microbe Interactions and Immunity
- T-cell and B-cell Immunology
- Plant Virus Research Studies
- Insect Resistance and Genetics
- Immune cells in cancer
- Mesenchymal stem cell research
- Plant Disease Resistance and Genetics
- Immunotherapy and Immune Responses
- CRISPR and Genetic Engineering
- Insect-Plant Interactions and Control
- Plant and Fungal Interactions Research
- Insect and Pesticide Research
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Fungal Biology and Applications
- Indoor Air Quality and Microbial Exposure
- Retinoids in leukemia and cellular processes
- Bacteriophages and microbial interactions
- Immune Cell Function and Interaction
- Insect Pest Control Strategies
- Dermatology and Skin Diseases
Rutgers, The State University of New Jersey
2015-2025
Qilu University of Technology
2024-2025
Southwest Petroleum University
2025
Taiyuan Central Hospital
2012-2024
Shanxi Medical University
1998-2024
Beijing Forestry University
2024
Chinese Academy of Tropical Agricultural Sciences
2015-2021
Xiangtan University
2021
United States Department of Agriculture
2021
National Center for Agricultural Utilization Research
2021
Abstract Bone metastasis of breast cancer makes patients suffer from pain, fractures, spinal cord compression, and hypercalcemia, is almost incurable. Although the mechanisms bone in cancers have been studied intensively, novel specific target will be helpful to development new therapeutic strategy cancer. Herein, we focused on microRNA tumor cell‐derived exosomes investigate communication between microenvironment cells. The expression miR‐20a‐5p primary murine marrow macrophages (BMMs),...
Quantitative real-time reverse-transcriptase PCR (qRT-PCR) is an important technique for analyzing differences in gene expression due to its sensitivity, accuracy and specificity. However, the stability of reference genes necessary ensure accurate qRT-PCR assessment interest. Perennial ryegrass (Lolium perenne L.) forage turf grass species temperate regions, but under various stresses has not been well-studied.In this study, 11 candidate were evaluated use as controls quantify perennial...
The Asian citrus psyllid (ACP) Diaphorina citri Kuwayama (Hemiptera: Psyllidae) is the insect vector of fastidious bacterium Candidatus Liberibacter asiaticus (CLas), causal agent greening disease, or Huanglongbing (HLB). widespread invasiveness and HLB in trees worldwide has underscored need for non-traditional approaches to manage disease. One tenable solution through deployment RNA interference technology silence protein-protein interactions essential ACP-mediated CLas invasion...
Osteosarcoma (OS) is the most frequent bone malignancy in human. Growing evidence suggests that circular RNAs (circRNAs) play a significant role regulating tumorigenesis and progression. Previously, circ_0001721 was identified upregulated OS tissues screened by circRNA microarrays. In current study, expression tissue samples cells were measured qRT-PCR. Its clinical value also explored. For part of functional assays, CCK-8, clone-forming, flow cytometric, Transwell, xenograft assays...
Jasmonic acid (JA) and methyl jasmonate (MeJA) regulate plant development, resistance to stress, insect attack by inducing specific gene expression. However, little is known about the mechanism of defense against herbivore at a protein level. Using high-resolution 2-D gel, we identified 62 MeJA-responsive proteins measured expression level changes.
Penicillium is a large genus of common molds with over 400 described species; however, identification individual species difficult, including for those that cause postharvest rots. In this study, blue rot fungi from stored apples and pears were isolated variety hosts, locations, years. Based on morphological cultural characteristics partial amplification the β-tubulin locus, isolates provisionally identified as several different Penicillium. These investigated further using suite molecular...
Abstract Corn defense systems against insect herbivory involve activation of genes that lead to metabolic reconfigurations produce toxic compounds, proteinase inhibitors, oxidative enzymes and behavior-modifying volatiles. Similar responses occur when the plant is exposed methyl jasmonate (MeJA). To compare between stalk borer feeding exogenous MeJA on a transcriptional level, we employed deep transcriptome sequencing methods following Ostrinia furnacalis leaf treatment. 39,636 were found be...
Abstract Orchardgrass ( Dactylis glomerata L.) is a long‐lived, cool‐season forage grass that commonly used for hay production. Despite its economic importance, orchardgrass genome remains relatively unexplored. In this study, we Illumina RNA sequencing to identify gene‐associated molecular markers, including simple sequence repeats SSR s) and single nucleotide polymorphisms SNP s), as well heat stress‐induced differentially expressed genes DEG in two genotypes, ‘Baoxing’ (heat resistant)...
Orchardgrass (Dactylis glomerata L.), is a well-known perennial forage species; however, rust diseases have caused noticeable reduction in the quality and production of orchardgrass. In this study, genetic diversity was assessed marker-trait associations for were examined using 18 EST-SSR 21 SCoT markers 75 orchardgrass accessions. A high level detected with an average index 0.369. For markers, 164 289 total bands obtained, which 148 (90.24%) 272 (94.12%) polymorphic, respectively. Results...
Psoriasis is an inflammatory disease related to dysfunctional immunity. The immunity may influence the haematopoietic microenvironment or haematopoiesis in psoriasis. However, direct evidence lacking. Our objective was investigate proliferation of hematopoietic cells from psoriatic patients and any link between promoter methylation status p15 p21 genes colony formation ability high proliferative potential colony-forming (HPP-CFCs). Marrow mononuclear were isolated bone marrow normal controls...
Superstorm Sandy provided an opportunity to study filamentous fungi (molds) associated with winter storm damage. We collected 36 morphologically distinct fungal isolates from flooded buildings. By combining traditional morphological and cultural characters analysis of ITS sequences (the DNA barcode), we identified 24 species that belong eight genera: Penicillium (11 species), Fusarium (four Aspergillus (three Trichoderma (two one each Metarhizium, Mucor, Pestalotiopsis, Umbelopsis. Then,...
Drought stress is a global problem, and the lack of water key factor that leads to agricultural shortages. MicroRNAs play crucial role in plant drought response; however, microRNAs their targets involved response have not been well elucidated. In present study, we used Illumina platform (https://www.illumina.com/) combined data from miRNA, RNA, degradome sequencing explore drought- organ-specific miRNAs orchardgrass (Dactylis glomerata L.) leaf root. We aimed find potential miRNA–mRNA...
Abstract Psoriasis displays both increased angiogenesis and microvascular dilation in the skin, while human dermal endothelial cells (HDMECs) are involved dilation. Whether functions of HDMECs altered psoriatic skin versus healthy remain unknown. Here, we isolated from 10 patients with psoriasis subjects compared angiogenesis, proliferation, migration cell metabolism between normal HDMECs. We found that morphology primary was comparable After passage, displayed larger size wider...
Psoriasis is a chronic and relapsing inflammatory disease of the skin associated with various immune abnormalities. It tempting to speculate that dysfunctional immunity may influence haematopoietic microenvironment or haematopoiesis in psoriasis. However, direct evidence involvement bone-marrow cells pathogenesis psoriasis lacking.To investigate proliferative activity patients link between promoter methylation status transcriptional p16 gene colony-forming ability high potential...
Different species of fungi usually share many common pathways but they also have some unique metabolic (e.g. those for specialised metabolites). It is not clear how gene expression patterns significantly contribute to the creation diverse volatile compounds. Based on research most VOCs, functions different fungal compounds are mainly as follows: inhibitory or synergistic effects other microorganisms, promoting growth in plants inducing a defensive response crops, and participating material...
Soil microorganisms play an important role in regulating the responses of plants to disease, but little is known regarding microbial community rhizosphere soil response diseases papaya. To clarify how abundance and composition papaya change with viral infection, resistant susceptible ringspot virus (PRSV) were inoculated PRSV field, differences communities between healthy analyzed. The physiochemical properties surrounding root system strongly affected by taxa, this did not have a...
The geo-inequality of COVID-19 risk has attracted a great deal research attention. In this study, the spatial correlation between community environment and incidence cases in 30 Chinese cities is discussed. spread disease analyzed based on timing monitoring at km2-grid level, with use publicly available data relating to housing prices, Gross Deomestic Product (GDP), medical facilities, consumer sites, public green spaces, industrial sites. results indicate substantial geographical variations...
In psoriasis CD4+CD25+ regulatory T cells are functionally deficient. The imbalance between and effector T-cell functions is important for inducing psoriasis. It reasonable to speculate that the dysfunctional activity of may originate partly from abnormal haematopoietic determined mainly by genetic background.To test hypothesis stem responsible in psoriasis.Bone marrow-derived CD34+ patients with (with a family history psoriasis) normal controls were differentiated into vitro. isolated an...