A5064901497- Autism Spectrum Disorder Research
- Child Nutrition and Feeding Issues
- Gut microbiota and health
- Plant Virus Research Studies
- Pesticide Residue Analysis and Safety
- Analytical chemistry methods development
- Family and Disability Support Research
- Plant biochemistry and biosynthesis
- Insect and Pesticide Research
- Analytical Chemistry and Chromatography
- Plant-Microbe Interactions and Immunity
- Pharmacological Effects and Assays
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Spondyloarthritis Studies and Treatments
- Genetics and Neurodevelopmental Disorders
- Pregnancy and preeclampsia studies
- Botanical Research and Chemistry
- Immune Response and Inflammation
- Diet and metabolism studies
- Advanced Chemical Sensor Technologies
- Insect-Plant Interactions and Control
- Mesenchymal stem cell research
- Infant Nutrition and Health
- Antibiotics Pharmacokinetics and Efficacy
Hebei Agricultural University
2024-2025
Fujian Medical University
2016-2025
Union Hospital
2016-2025
Sichuan University
2015-2025
Changzhi Medical College
2023-2025
Tokyo Metropolitan University
2023-2024
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2024
Chongqing Medical University
2015-2024
Children's Hospital of Chongqing Medical University
2015-2024
Chengdu University of Traditional Chinese Medicine
2024
Some previous studies have identified bacteria in semen as being a potential factor male infertility. However, only few types of were taken into consideration while using PCR-based or culturing methods. Here we present an analysis approach next-generation sequencing technology and bioinformatics to investigate the associations between bacterial communities quality. Ninety-six samples collected examined for communities, measuring seven clinical criteria quality (semen volume, sperm...
High salinity is one of the most serious threats to crop production. To understand molecular basis plant responses salt stress better, suppression subtractive hybridization (SSH) and microarray approaches were combined identify potential important or novel genes involved in early stage tomato severe stress. First, SSH libraries constructed for root tissue two cultivated (Solanum lycopersicum) genotypes: LA2711, a salt-tolerant cultivar, ZS-5, salt-sensitive compare treatment non-treatment...
Restricted diets and inadequate nutrient intake of children with autism spectrum disorder (ASD) have been reported. This study examined the nutritional statuses ASD relationships between their behaviors intake. A total 154 (age = 5.21 ± 1.83 years) 73 typically-developing (TD) 4.83 0.84 from Chongqing, China, were enrolled. The severity was evaluated using Childhood Autism Rating Scale (CARS). serum ferritin, folate, vitamin B12, 25(OH) D, concentrations in determined. All participants...
Eighty-one stool samples from Taiwanese were collected for analysis of the association between gut flora and obesity. The supervised showed that most, abundant genera bacteria in normal (from people with a body mass index (BMI)<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mo>≤</mml:mo></mml:mrow></mml:math>24) Bacteroides (27.7%), Prevotella (19.4%), Escherichia (12%), Phascolarctobacterium (3.9%), Eubacterium (3.5%). most case (with BMI<mml:math...
Dysbiosis of gut microbiota are commonly reported in autism spectrum disorder (ASD) and may contribute to behavioral impairment. Vitamin A (VA) plays a role regulation microbiota. This study was performed investigate the VA changes functions children with ASD. Sixty four, aged 1 8 years old ASD completed 6-month follow-up intervention. High-performance liquid chromatography used assess plasma retinol levels. The Autism Behaviour Checklist (ABC), Childhood Rating Scale (CARS) Social...
To determine the relationship of gut microbiota and its metabolites with autism spectrum disorder (ASD)-like behaviors preliminarily explore potential molecular mechanisms, fecal from donors ASD typically developing (TD) were transferred into germ-free (GF) mice to obtain ASD-FMT TD-FMT mice, respectively. Behavioral tests conducted on these after 3 weeks. 16S rRNA gene sequencing cecal contents untargeted metabolomic analysis cecum, serum, prefrontal cortex performed. Untargeted...
Objectives: This study was designed to investigate the alteration of gut microbiota and its metabolites correlation with core symptom in sleep problems children autism spectrum disorders (ASD). Methods: One hundred twenty ASD diagnosed by Diagnostic Statistical Manual Mental Disorders (DSM-5) criteria were enrolled our study. The Autism Behavior Checklist (ABC), Childhood Rating Scale (CARS), Social Responsiveness (SRS) used assess symptoms, Children Sleep Habits Questionnaire (CSHQ)...
Abstract Background Human health is seriously threatened by antibiotic-induced intestinal disorders. Herein, we aimed to determine the effects of Autoinducer-2 (AI-2) combined with Lactobacillus rhamnosus GG ( LGG ) on barrier function dysbiosis neonatal mice. Methods An mouse model was created using antibiotic cocktails, and mice were randomized into control, AI-2, , + AI-2 groups. Intestinal short-chain fatty acids concentrations detected mass spectrometry chemiluminescence, respectively....
Feed efficiency appears to vary even within closely related pigs, and may be partly affected by the diversity in composition function of gut microbes. To investigate components functional differences microbiota low high feed (FE) throughput sequencing de novo metagenomics were performed on pig cecal contents. Pigs selected pairs with conversion ratio. The microorganisms individuals different clustered according diversity. genus Prevotella was most enriched both groups, abundance species sp....
The daisy-like flowers of pyrethrum (Tanacetum cinerariifolium) are used to extract pyrethrins, a botanical insecticide with long history safe and effective use. Pyrethrum also contain other potential defense compounds, particularly sesquiterpene lactones (STLs), which represent problematic allergenic residues in the extracts that removed by industry. STLs stored glandular trichomes present on achenes, have been shown be active against herbivores, micro-organisms below-ground competition...
Objectives: This study was designed to investigate the vitamin A (VA) and D (VD) levels in children with autism spectrum disorders (ASD) determine whether co-deficiency of VA VD exacerbates clinical symptoms autistic children. Methods: The Autism Behavior Checklist, Childhood Rating Scale (CARS), Social Responsiveness (SRS) were used assess 332 diagnosed as ASD. And Gesell Developmental (GDS) evaluate neurodevelopment Anthropometric measurement questionnaire results compared for all 197 age-...
The present study sought to identify a panel of DNA markers for noninvasive diagnosis using cell-free (cfDNA) from urine supernatant or cellular sediments hematuria patients. A 48 bladder cancer-specific genes was selected. next-generation sequencing-based assay with cfDNA barcode-enabled single-molecule test employed. Mutation profiles blood, urine, and tumor sample 16 cancer patients were compared. Next, urinary prospectively collected 125 (92 cases 33 controls) analyzed the 48-gene panel....
To investigate whether gut microbiota is associated with vitamin A nutritional levels in children persistent diarrhea, a total of 59 pediatric patients diarrhea aged 1-12 months were selected from the Department Gastroenterology at Children's Hospital Chongqing Medical University, China. Subjects hospitalized and divided into VA-deficient (n = 30) VA-normal 29) groups according to their venous serum retinol levels. Fecal samples all subjects collected immediately after admission analyzed by...
High prevalence of sleep problems have been reported in children with Autism Spectrum Disorder (ASD). This study aims to investigate the conditions ASD China, and explore relationship between common core symptoms developmental levels.Using a cross-sectional design, we included 2 7-year-old from 13 cities China: 1310 1158 typically-developing (TD) children. The neurodevelopmental level was evaluated revised Children Neuropsychological Behavior Scale (CNBS-R2016). were diagnosed DSM-5 Child...
Summary The model plant Nicotiana benthamiana is an increasingly attractive organism for the production of high‐value, biologically active molecules. However, N. accumulates high levels pyridine alkaloids, in particular nicotine, which complicates downstream purification processes. Here, we report a new assembly genome as well generation low‐nicotine lines by CRISPR/Cas9‐based inactivation berberine bridge enzyme‐like proteins (BBLs). Triple quintuple mutants accumulated three to four times...