A5079394835- Cancer-related molecular mechanisms research
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Plant and animal studies
- Plant-Microbe Interactions and Immunity
- Plant Gene Expression Analysis
- Epigenetics and DNA Methylation
- Plant and Fungal Species Descriptions
- Algal biology and biofuel production
- MicroRNA in disease regulation
- Research in Cotton Cultivation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Legume Nitrogen Fixing Symbiosis
- Pesticide and Herbicide Environmental Studies
- Plant tissue culture and regeneration
- Plant Virus Research Studies
- Insect Resistance and Genetics
- Weed Control and Herbicide Applications
- Protein Degradation and Inhibitors
- Genomics and Phylogenetic Studies
- Retinoids in leukemia and cellular processes
- Sperm and Testicular Function
- Plant Molecular Biology Research
- Estrogen and related hormone effects
- Proteins in Food Systems
Guangxi Medical University
2025
Biotechnology Research Institute
2013-2024
Jimei University
2024
Xi'an Jiaotong University
2024
Fujian Academy of Agricultural Sciences
2024
University Gastroenterology
2024
Nanjing Medical University
2002-2023
Chinese Academy of Agricultural Sciences
2003-2023
City Of Hope National Medical Center
2003-2023
Changzhou No.2 People's Hospital
2021-2023
Constituting approximately 10% of flowering plant species, orchids (Orchidaceae) display unique flower morphologies, possess an extraordinary diversity in lifestyle, and have successfully colonized almost every habitat on Earth. Here we report the draft genome sequence Apostasia shenzhenica, a representative one two genera that form sister lineage to rest Orchidaceae, providing reference for inferring content structure most recent common ancestor all extant improving our understanding their...
Orchids make up about 10% of all seed plant species, have great economical value, and are specific scientific interest because their renowned flowers ecological adaptations. Here, we report the first draft genome sequence a lithophytic orchid, Dendrobium catenatum. We predict 28,910 protein-coding genes, find evidence whole duplication shared with Phalaenopsis. observed expansion many resistance-related suggesting powerful immune system responsible for adaptation to wide range niches. also...
Vitamin K2 is a critical nutrient required for blood clotting that also plays an important role in bone formation. supplementation up-regulates the expression of markers, increases density vivo, and used clinically management osteoporosis. The mechanism vitamin action formation was thought to involve its normal as essential cofactor γ-carboxylation matrix proteins. However, there evidence suggests has transcriptional regulatory function. bound activated orphan nuclear receptor SXR induced...
Single nucleotide polymorphisms (SNPs) have emerged as the genetic marker of choice for mapping disease loci and candidate gene association studies, because their high density relatively even distribution in human genomes. There is a need systems allowing medium multiplexing (ten to hundreds SNPs) with throughput, which can efficiently cost-effectively generate genotypes very large sample set (thousands individuals). Methods that are flexible, fast, accurate cost-effective urgently needed....
Aging is usually characterized with inflammation and disordered bile acids (BAs) homeostasis, as well gut dysbiosis. The pathophysiological changes during aging are also sexual specific. However, it remains unclear about the modulating process among microbiota, BA metabolism, aging. In this study, we established a direct link between microbiota profile in liver, serum, four intestinal segments of both sexes remodeling by co-housing old mice young ones. We found reduced Actinobacteria male...
Leaf senescence is an important developmental programmed degeneration process that dramatically affects crop quality and yield. The regulation of highly complex. Although regulatory genes have been well characterized in model species such as Arabidopsis rice, there little information on the control this cotton. Here, cotton (Gossypium hirsutum L.) leaves was investigated over a time course including young leaf, mature leaf samples from different stages using RNA-Seq.
CD8 T cells play a key role in mediating protective immunity against selected pathogens after vaccination. Understanding the mechanism of this protection is dependent upon definition heterogeneity and complexity cellular immune responses generated by different vaccines. Here, we identify previously unrecognized subsets based analysis gene-expression patterns within single show that they are differentially induced Three prime-boost vector combinations encoding HIV Env stimulated...
Colorectal cancer (CRC) is a type of with mortality rate among the highest worldwide owing to its high metastasis. Therefore, inflammation-associated metastasis in development CRC currently topic considerable interest. In present study, pro-inflammatory cytokine interleukin-4 (IL-4) was identified promote epithelial-mesenchymal transition (EMT) cells. However, enhancing effect IL-4 more evident HCT116 cells compared RKO Accordingly, an increased expression level STAT6 observed Further...
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders; it characterized by polycystic ovaries, hyperandrogenism and chronic anovulation. To obtain a global view those genes that might be involved in development this complex clinical disorder, we used recently developed cDNA microarray technology to compare differential gene expressions between normal human ovaries from PCOS patients. A total 9216 clones randomly selected commercial library were screened. Among them,...
Glycosylation is a prominent strategy to optimize the pharmacokinetic and pharmacodynamic properties of drug-like small-molecule scaffolds by modulating their solubility, stability, bioavailability, bioactivity. Glycosyltransferases applicable for "sugarcoating" various acceptors have been isolated characterized from plants bacteria, but remained cryptic filamentous fungi until recently, despite frequent use some whole-cell biocatalytic glycosylations. Here, we bioinformatic genomic tools...
We characterized cellular and molecular mechanisms involved in spermatogenesis following short-term heat exposure of murine testis. For these studies, we utilized a proteomic approach with two-dimensional gel electrophoresis (2DE) analyses mass spectroscopic identification proteins altered expression mouse testes at different times after shock. established proteome reference map from 7-wk-old testis linked to federated database. used tools analyze quantitative variations the tissue over time...
Triple-negative breast cancer (TNBC) is an aggressive form of carcinoma with a poor prognosis. Recent evidence suggests that some patients TNBC harbour germ-line mutations in DNA repair genes which may render their tumours susceptible to novel therapies such as treatment PARP inhibitors. In the present study, we have investigated hospital-based series 40 German for presence BRCA1, BRCA2, PALB2, and BRD7 genes. Microfluidic array PCR next-generation sequencing was used BRCA1 BRCA2 analysis...
Gymnadenia conopsea (L.) R. Br. is an important perennial terrestrial photosynthetic orchid species whose microbiomes are considered to play role in helping its germination and growth. However, the assemblage of G. root-associated microbial communities poorly understood. The compositions fungal bacterial from roots corresponding soil samples across distinct biogeographical regions two significantly different altitudes were characterized at vegetative reproductive growth stages. geographical...
Abstract BACKGROUND Hairtail ( Trichiurus haumela ) surimi exhibits poor gelation properties and a dark gray appearance, which hinder its utilization in high‐quality gel products. The effect of Pickering emulsions stabilized by myofibrillar proteins (MPE) on the hairtail has been unclear. In particular, impact MPE under NaCl KCl treatments quality gels requires further elucidation. RESULTS treated with or (Na‐MPE, K‐MPE) were added to amounts 10–70 g kg −1 . addition 50 Na‐MPE K‐MPE improved...
Glyphosate-resistant (GR) crops have been adopted on a massive scale by North and South American farmers. Currently, about 80% of the 120 million hectares global genetically modified (GM) are GR crop varieties. However, adoption plants in China has not occurred at same pace, owing to several factors including, among other things, labour markets residual effects glyphosate transgenic plants. Here, we report co-expression codon-optimized forms GR79 EPSPS N-acetyltransferase (GAT) genes cotton....