A5029909108- Mosquito-borne diseases and control
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Malaria Research and Control
- COVID-19 Clinical Research Studies
- Bacterial Infections and Vaccines
- Insect symbiosis and bacterial influences
- Herpesvirus Infections and Treatments
- Retinal and Optic Conditions
- Viral Infections and Outbreaks Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Global Public Health Policies and Epidemiology
- Influenza Virus Research Studies
- Pneumonia and Respiratory Infections
- Long-Term Effects of COVID-19
- Travel-related health issues
- Infectious Encephalopathies and Encephalitis
- Sepsis Diagnosis and Treatment
- Poxvirus research and outbreaks
- Hepatitis Viruses Studies and Epidemiology
- Bacillus and Francisella bacterial research
- Viral gastroenteritis research and epidemiology
- Drug-Induced Adverse Reactions
Instituto Evandro Chagas
2014-2025
Fundação Oswaldo Cruz
2014-2024
D’Or Institute for Research and Education
2022-2024
Faculdades Oswaldo Cruz
2023
National Institute of Infectious Diseases
2022
Fundação Estadual de Produção e Pesquisa em Saúde
2020
Harvard University
2020
Universidade Federal do Rio de Janeiro
2006-2017
Shanghai Public Health Clinical Center
2016
Secretaria Municipal de Saúde
2016
A low-cost, equipment-free rapid antigen test distinguishes dengue virus serotypes and Zika in patient sera without detectable cross-reactivity.
The objective of this study was to identify socioeconomic and environmental factors associated with the incidence visceral leishmaniasis in city Teresina, Piauí State, Brazil. This an ecological based on 1,744 cases reported from 1991 2000, city's neighborhoods served as unit analysis. Mean annual rates were related demographic indicators a vegetation index derived remote sensing images by means spatial multiple linear regression models. highest mostly located peripheral areas. Multivariate...
Abstract Brazil, which is hyperendemic for dengue virus (DENV), has had recent Zika (ZIKV) and (CHIKV) Chikungunya outbreaks. Since March 2016, CHIKV the arbovirus infection most frequently diagnosed in Rio de Janeiro. In analysis of 1835 syndromic patients, screened by real time RT-PCR, 56.4% cases were attributed to CHIKV, 29.6% ZIKV, 14.1% DENV-4. Sequence analyses from sixteen samples revealed that East-Central-South-African ( ECSA) genotype been circulating Brazil since 2013 [95%...
There is limited information on the inequity of access to vaccination in low-and-middle-income countries during COVID-19 pandemic. Here, we described progression Brazilian immunisation program for COVID-19, and association socioeconomic development with rates, considering potential protective effect primary health care coverage.
In 2013, the World Health Organization (WHO) withdrew recommendation of booster doses yellow fever (YF) vaccine, based on retrospective and cross-sectional studies that showed lifelong protective immunity from a single dose. Currently, transmission in Brazil occurs only through jungle (sylvatic) cycle. However, high vector density Aedes aegypti , which transmits other orthoflaviviruses, is concern for expansion YF regions country. We conducted cohort study to assess duration vaccine-induced...
We tested 210 dengue virus‒negative samples collected from febrile patients during a virus type 4 outbreak in Rio de Janeiro April 2013 and found 3 positive for Zika virus. Our findings support previously published entomological data suggesting was introduced into Brazil October 2012-May 2013.
Tuberculosis is one of the leading causes death from infectious diseases worldwide, mainly after human immunodeficiency virus (HIV) epidemics. Patient with HIV-related illness are more likely to present severe TB due immunosuppression. Very few studies have explored HIV/TB co-infection in critically ill patients. The goal this study was analyze factors associated long-term mortality patient disease coinfected TB.We conducted a retrospective an reference center Brazil that included all...
To estimate vaccine effectiveness after the first and second dose of ChAdOx1 nCoV-19 against symptomatic COVID-19 infection in a socially vulnerable community Brazil when Gamma Delta were predominant variants circulating.We conducted test-negative study Complexo da Maré, largest group slums (n = 16) Rio de Janeiro, Brazil, from January 17, 2021 to November 27, 2021. We selected RT-qPCR positive negative tests broad testing program. The primary outcome was (positive test with at least one...
Resumo O Ministério da Saúde declarou em 03 de fevereiro 2020 estado emergência saúde pública importância nacional decorrência pandemia pelo novo coronavírus SARS-CoV-2. Com isso, o IBGE adiou a realização do Censo Demográfico e passou formular uma PNAD COVID-19. inquérito contou com amostra total 349 mil pessoas cerca 200 domicílios. Do população-residente brasileira, estimou maio/2020 que 24,0 milhões (11,4%) tiveram menos um dos sintomas síndrome gripal (SG). Desse contingente, 20,2...
The consumption of antibiotics is one the metrics used to evaluate impact antimicrobial stewardship programs (ASP). aim this study was determine prevalence antibiotic in Brazilian intensive care units (ICUs) and estimate deviation prescribed daily dose (PDD) from defined (DDD).
Abstract With the continued emergence of variants concern, global threat COVID-19 persists, particularly in low- and middle-income countries with limited vaccine access. Protein-based vaccines, such as SCB-2019, can be produced on a large scale at low cost while antigen design adjuvant use modulate efficacy safety. While effective humoral immunity against SARS-CoV-2 has been shown to depend both neutralization Fc-mediated immunity, data effectiveness protein-based vaccines enhanced is...
ABSTRACT Objective To describe the profile of cases mpox in city Rio de Janeiro between June and November 2022. Methods This was a descriptive study secondary data obtained from notification forms. Socioeconomic, clinical spatial were analyzed. Results Of 928 cases, 93.7% male, 85.0% cisgender 65.6% homosexual, 41.8% 30 39 years old, 41.0% White race/skin color. A total 34.5% had immunosuppression due to illness, 41.9% reported their HIV status as being positive. The most prevalent signs...
RESUMO Objetivo Descrever o perfil dos casos de mpox na cidade do Rio Janeiro, entre junho e novembro 2022. Métodos Estudo descritivo dados secundários das fichas notificação mpox. Foram analisados socioeconômicos, clínicos espaciais. Resultados Dos 928 casos, 93,7% foram sexo masculino, 85,0% homem cisgênero, 65,6% homossexual, 41,8% 30 39 anos 41,0% brancos. Apresentavam imunodepressão por doença 34,5%, 41,9% informaram sorologia positiva prévia para vírus da imunodeficiência humana. Os...
The concentrations of lopinavir and ritonavir in seminal blood plasma the human immunodeficiency virus (HIV) viral load were quantified by HPLC Nuclisens® assay, respectively, a cross-sectional study 16 HIV-1–infected Brazilian men under stable treatment with lopinavir/ritonavir containing antiretroviral regimen. Semen samples collected on 2 occasions: at 6 to 60 minutes before ("trough"), 5 hours after ("peak") ingestion regular doses lopinavir/ritonavir. Median levels 120.6 ng/mL (range,...
The aim of this article is to examine regional differences in mortality associated with influenza from 2006 2010 Brazil. Syndromic surveillance, which includes deaths pneumonia and recorded the Mortality Information System, only showed an increase during pandemic South, Southeast, Central, regions. In these regions, especially occurred July September 2009. A review confirmed cases reported System for Notifiable Diseases different temporal patterns South/Southeast North/Northeast, November...
A pandemia de influenza H1N1 em 2009 foi considerada emergencia saude publica internacional, que levou ao rapido desenvolvimento vacinas para prevenir sua disseminacao. Relatamos um caso uma paciente apresentou purpura Henoch-Schonlein horas apos a aplicacao da vacina contra unidade cuidado primario no Rio Janeiro, Brasil. Houve boa resposta clinica pronta instituicao corticoterapia intensiva, apesar do aumento, embora nao alarmante, excrecao urinaria proteinas acima dos niveis normais.
In Brazil, until 2004, the immunization policy against diphtheria involved childhood vaccination with no official routine booster dose administered after 15 years of age. This study assessed functional antibody levels among blood donors. A total 140 samples were collected, and antitoxin evaluated by Vero cell neutralization test. The mean age population was 34 old (range: 18-61 years); 37.8% females 62.2% males. Overall, 30.7% (95%, CI: 23.4-38.7) individuals presented neutralizing titers <...
Purpose To describe a case of Acute Zika infection with ocular involvementMethods: Review clinical recordsResults: Patient presented sudden blurred vision in both eyes during an acute episode zika virus infection. Ophthalmological examination revealed picture multifocal choroiditis eyes. Lesions improved and visual acuities returned to normal level without any treatment.Conclusion: Ocular changes is rare condition. Patiens may present spontaneous recovery