A5033391019- Shoulder Injury and Treatment
- Bone fractures and treatments
- Hip and Femur Fractures
- Shoulder and Clavicle Injuries
- Trauma Management and Diagnosis
- Organic Light-Emitting Diodes Research
- Neuropeptides and Animal Physiology
- Elbow and Forearm Trauma Treatment
- Nanomaterials and Printing Technologies
- Osteoarthritis Treatment and Mechanisms
- Advanced Sensor and Energy Harvesting Materials
- Chemokine receptors and signaling
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Organic Electronics and Photovoltaics
- Autophagy in Disease and Therapy
- Adipose Tissue and Metabolism
- Sirtuins and Resveratrol in Medicine
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Quantum Dots Synthesis And Properties
- Cancer, Stress, Anesthesia, and Immune Response
- Spinal Fractures and Fixation Techniques
- Healthcare Systems and Public Health
Xi'an Jiaotong University
2015-2025
Xi'an Honghui Hospital
2013-2025
First Affiliated Hospital of Xi'an Jiaotong University
2015-2023
Shanghai University of Medicine and Health Sciences
2023
XinHua Hospital
2021-2022
Shanghai Jiao Tong University
2016-2021
Nanjing University
2017
China Jiliang University
2011
Autophagy is activated during nutritionally depleted or hypoxic conditions to facilitate cell survival. Because growth plate an avascular and tissue, autophagy may have a crucial role chondrogenesis; however, the functional underlying mechanism of in regulation remains elusive. In this study, we generated TamCart Atg7-/- (Atg7cKO) mice explore endochondral ossification. Atg7cKO exhibited retardation associated with reduced chondrocyte proliferation differentiation, increased apoptosis....
The critical regulation of the peripheral circadian gene implicated in osteoarthritis (OA) has been recently recognized; however, causative role and clinical potential rhythm attributable to such effects remain elusive. purpose this study was elucidate a Bmal1 human cartilage pathophysiology osteoarthritis. In our present study, mRNA protein levels genes, including nicotinamide adenine dinucleotide oxidase (NAD+) sirtuin 1 (Sirt1), knee articular were determined. OA cartilage, both NAD+...
Total hip arthroplasty is a reliable therapeutic intervention in patients with ankylosing spondylitis, whom the aims of surgery are to reduce pain, restore function and improve quality life. The current study retrospective analysis clinical radiographic findings consecutive series ankylosis associated severe spondylitis who underwent bilateral primary total using non-cemented components.From June 2008 May 2012, was performed on 34 hips 17 caused by spondylitis. included 13 men 4 women mean...
ABSTRACT Neuropeptide Y (NPY) is known to regulate bone homeostasis; however, its functional role as a risk factor during osteoarthritis (OA) remains elusive. In this study, we aim investigate the direct effect of NPY on degradation cartilage and progression OA explore molecular events involved. was overexpressed in human accompanied with increased expression NPY1 receptor (NPY1R) NPY2 (NPY2R). Stressors such cold exposure resulted peripheral release from sympathetic nerves, which turn...
Abstract Background Clavicle fractures associated with ipsilateral coracoid process are very rare, limited literature reporting only a few cases. This study reports on 27 patients concomitant of the clavicle and who were followed for more than 12 months. Material methods retrospective reviewed charts skeletally mature traumatic treated at authors’ institution. Each patient was regularly post-treatment. Radiographs assessed bone union implant integrity, while clinical evaluations included...
Gallbladder cancer (GBC) is commonly regarded as one of the most lethal malignant tumor types with poor prognosis. Kinesin family member 15 (KIF15) reported to be tightly related progression multiple which, however, has not been clarified in GBC so far. KIF15 was significantly up-regulated clinical tissues compared that para-carcinoma and expression level also correlated malignancies. In addition tissues, cells exhibited a high abundance KIF15. After down-regulating via lentiviral...
Progranulin (PGRN), a multifunctional protein implicated in embryonic development and immune response, was recently introduced as novel marker of chronic inflammation related with insulin resistance obesity type 2 diabetes mellitus. However, the potential mechanisms PGRN on signaling pathways are poorly understood. In this study, mediated chemotaxis RAW264.7, impaired action stimulated production inflammatory factors adipocytes, which accompanied by increased c-Jun N-terminal kinase (JNK)...
A novel solution‐processed zinc oxide (ZnO)‐based electron injection layer (EIL) has been developed with an easy method. The inverted organic light‐emitting diode (OLED) pristine ZnO as EIL shows improved property compared to that thermally evaporated Cs 2 CO 3 , and a maximum efficiency of 58.5 cd −1 achieved for green phosphorescent OLED. However, when the is applied OLED using poly(9,9‐dioctylfluorene‐co‐benzothiadiazole) (F8BT) emissive layer, it found luminance remains at low level...
Associations of High-density lipoprotein (HDL) cholesterol, low-density (LDL) total cholesterol (CHL), and triglyceride (TRG) concentrations with risk biliary tract cancer (BtC) were conflicting in observational studies. We aim to investigate the causal link between circulating lipids BtC using genetic information.
Abstract Background Although most cases of humeral shaft nonunion respond well to surgical intervention, surgeons still encounter patients with who have already undergone repeated surgeries for nonunion. This study retrospectively analyzed the efficacy double locking compression plate (LCP) fixation in combination autogenous iliac crest bone grafting recalcitrant Methods A consecutive series aseptic underwent treatment between May 2010 and August 2017 our institution. Standardized included...
Abstract Background Although clavicle fractures are common injuries in adults, simultaneous bilateral rarely reported. The present report describes 13 patients with traumatic who were treated surgical management and followed for more than 12 months postoperatively. Methods This retrospective chart review involved skeletally mature injuries. Patients up at least after surgery included. Data regarding the patients’ demographics, injury characteristics, fracture classification, comorbidities,...
Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, and endocrine systems. We sought determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension elucidate underlying mechanism.MCT-intoxicated rats were treated with gradient doses of TG, or without N (G)-nitro-l-arginine methyl ester. The levels molecules involving regulation nitric oxide mitogen-activated protein kinase pathways...
Progranulin (PGRN) is an autocrine growth factor that exerts crucial roles within cartilage tissue; however, the molecular mechanisms underlying PGRN-mediated homeostasis remain elusive. In present study, we investigated role of PGRN in regulating chondrocyte and its therapeutic potential for managing osteoarthritis (OA). We found levels are significantly increased human mild OA expression decreased severe OA. vitro, treatment primary rat chondrocytes with recombinant enhanced collagen type...
The performances of quantum dot light-emitting diodes (QD-LEDs) with doped QD emitting layers are enhanced by inserting a suitable interlayer.
Longstanding humeral shaft nonunion is uncommon because fractures often respond well to conservative and surgical treatments. However, when it occurs, the treatment of longstanding challenging. This study a retrospective analysis clinical radiographic findings in consecutive series patients with nonunions who underwent locking compression plate (LCP) fixation autogenous iliac crest bone grafting. Six were surgically treated at Xi'an Hong Hui Hospital for between February 2011 June 2015. Four...