A5070530684- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Esophageal Cancer Research and Treatment
- Liver Disease and Transplantation
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Bariatric Surgery and Outcomes
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Vagus Nerve Stimulation Research
- Gastrointestinal Tumor Research and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Tracheal and airway disorders
- Crime Patterns and Interventions
- Biliary and Gastrointestinal Fistulas
- Diet and metabolism studies
- Pediatric Hepatobiliary Diseases and Treatments
- Autopsy Techniques and Outcomes
- Estrogen and related hormone effects
Northwell Health
2013-2023
Feinstein Institute for Medical Research
2016-2023
Evidence (Italy)
2023
Michigan Department of Education
2023
American Urological Association
2023
Long Island Jewish Medical Center
2013-2021
North Shore University Hospital
2013-2021
Hofstra University
2012-2021
Jewish Hospital
2012-2018
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2018
We aimed to determine if botulinum toxin injection into the pyloric sphincter improves gastric emptying and reduces symptoms in patients with idiopathic gastroparesis.Patients gastroparesis not responding prokinetic therapy underwent (80-100 U, 20 U/ml) sphincter. Gastric scintigraphy was performed before 4 wk after treatment. Total symptom scores were obtained from sum of eight upper GI graded on a scale 0 (none) (extreme).Ten entered study. The mean percentage solid retention at h improved...
To describe a multicenter experience using an endoscopic suturing device for management of gastrointestinal (GI) defects and stent anchorage.Endoscopic closure GI including perforations, fistulas, anastomotic leaks as well anchorage has improved with technological advances. An (OverStitch; Apollo Endosurgery Inc.) been used.Retrospective study consecutive patients who underwent and/or were enrolled between March 2012 January 2014 at multiple academic medical centers. Data regarding...
Objective Although gastric per-oral endoscopic myotomy (G-POEM) is considered a promising technique for the management of refractory gastroparesis, high-quality evidence limited. We prospectively investigated efficacy and safety G-POEM in unselected patients with gastroparesis. Design In five tertiary centres, symptomatic gastroparesis to standard medical therapy confirmed by impaired emptying were included. The primary endpoint was clinical success, defined as at least one score decrease...
OBJECTIVE: The aim of this study was to determine if botulinum toxin injection in the gastroesophageal junction improves symptoms patients with noncardiac chest pain a spastic esophageal motility disorder. METHODS: Twenty-nine nonachalasia, nonreflux-related disorders were enrolled open label trial at junction. Chest major complaint all patients. Symptoms pain, dysphagia, regurgitation, and heartburn scored before 1 month after injection. A response defined as least 50% reduction symptom...
We developed an immunoperoxidase technique using a monoclonal antibody to the estradiol receptor (ER) identify immunoreactive ER (iER) in breast carcinomas and compared this with conventional dextran-coated charcoal (DCC) steroid binding assay. also examined relationship between iER response therapy patients advanced cancer. found iER-positive cells 60 of 90 (66.7%); correlated DCC assay (r = 0.76; P less than .001). Of these, 56 were be assessable for endocrine therapy. Twenty-two showed...
Estrogen receptor (ER) in human breast cancer tissues was demonstrated paraffin sections as well frozen by immunoperoxidase methods using monoclonal antibody (H222) against ER. The avidin-biotin-peroxidase complex method used for the fixed cold buffered formalin, and peroxidase-antiperoxidase sections. results were compared with ER content respective tumor tissue determined dextran-coated charcoal assay. specific staining located exclusively nuclei of cells both Differences intensity...
Quantifications of gastro‐oesophageal anatomy in cadavers have led some to identify the lower oesophageal sphincter (LOS) with anatomical gastric sling‐clasp fibres at oesophago‐cardiac junction (OCJ). However, vivo studies others argue for two overlapping components proximally displaced from OCJ: an extrinsic crural skeletal muscle and intrinsic physiological circular smooth‐muscle within abdominal oesophagus. Our aims were separate quantify smooth sphincteric pharmacologically clarify...
High-frequency catheter-based ultrasound (US) transducers can be inserted into the esophagus transnasally to evaluate esophageal wall structures. Studies were performed in two sheep specimens vitro, 17 healthy human subjects, and 16 patients with abnormalities (eight achalasia, four scleroderma, three carcinoma, one esophagitis). In specimens, endoluminal US delineated seven layers of wall; these results correlated closely histologic findings. Real-time normal was during resting swallowing....