- Advanced Neuroimaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Ear and Head Tumors
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Salivary Gland Tumors Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Medical Imaging and Pathology Studies
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury Research
- Fetal and Pediatric Neurological Disorders
- Neurological Complications and Syndromes
- Head and Neck Surgical Oncology
- Retinal Diseases and Treatments
- Cancer Treatment and Pharmacology
- Intracerebral and Subarachnoid Hemorrhage Research
- Autoimmune Neurological Disorders and Treatments
- MRI in cancer diagnosis
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Trauma and Emergency Care Studies
Tohoku University
2009-2022
Tohoku University Hospital
2017-2022
Murata (United States)
2014
Mildmay Uganda
2014
Institute of Brain and Blood Vessels
2006
Moyamoya disease is an idiopathic occlusive cerebrovascular disorder with abnormal microvascular proliferation. We investigated the clinical utility of leptomeningeal high signal intensity (ivy sign) sometimes seen on fluid-attenuated inversion recovery images in disease.We examined relationship between degree ivy sign and severity ischemic symptoms 96 hemispheres 48 patients disease. classified each cerebral hemisphere into 4 regions from anterior to posterior. In 192 24 patients, we...
Intraventricular hemorrhage (IVH) on initial computed tomography (CT) was reported to predict lesions of diffuse axonal injury (DAI) in the corpus callosum (CC) subsequent magnetic resonance imaging (MRI). We aimed examine relationship between CT findings and DAI detected MRI as well severity IVH (IVH score) (DAI staging). A consecutive 140 patients with traumatic brain (TBI) who underwent within 30 days after onset were revisited. reviewed their for following six findings: Status basal...
<h3>BACKGROUND AND PURPOSE:</h3> During surgery to treat an aneurysm in the anterior communicating artery, injury subcallosal a perforator of may lead infarction that produces basal forebrain amnesia after surgery. Our purpose was examine whether 3D MR imaging can detect artery patients with for aneurysm. <h3>MATERIALS METHODS:</h3> We evaluated 3D–T2-weighted images obtained median 4 months treatment presence infarcted foci 10 consecutive postoperative amnesia. Because and its neighboring...
OBJECTIVEThe objective of this study was to test the hypothesis that midline (interhemispheric or perimesencephalic) traumatic subarachnoid hemorrhage (tSAH) on initial CT may implicate same shearing mechanism underlies severe diffuse axonal injury (DAI).METHODSThe authors enrolled 270 consecutive patients (mean age [± SD] 43 ± 23.3 years) with a history head trauma who had undergone within 24 hours and brain MRI 30 days. Six findings, including intraventricular (IVH) tSAH, were used as...
We compared Canadian computed tomography (CT) head rule (CCHR) and New Orleans Criteria (NOC) in predicting important CT findings patients with mild traumatic brain injury (TBI). included 142 consecutive TBI [Glasgow coma scale (GCS) 13–15] who showed at least one of the risk factors stated CCHR or NOC. introduced two scores: a from A patient's score represented sum number positive items. examined relationship between scores items presence findings. Only was significantly associated...
Background The aims of this study were to investigate glaucomatous morphological changes quantitatively in the visual cortex brain with voxel-based morphometry (VBM), a normalizing MRI technique, and clarify relationship between damage regional patients open-angle glaucoma (OAG). Methods Thirty-one OAG (age: 55.9 ± 10.7, male: female = 9: 22) 20 age-matched controls 54.9 9.8, 10: 10) included study. cross-sectional area (CSA) optic nerve was manually measured T2-weighed MRI. Images acquired...
Abstract Background Treatment options for patients suffering brainstem gliomas are quite limited as surgery is not an option against intrinsic tumors at and chemotherapy generally failed to demonstrate its efficacy. Intracerebral convection-enhanced delivery (CED) a novel approach administering with brain tumors. We present the results of phase I trial CED nimustine hydrochloride (ACNU), designed determine maximum tolerable concentration ACNU, recurrent gliomas. Methods Sixteen patients,...
To determine the viability of using magnetic resonance imaging measurement optic nerve morphology as an objective analysis glaucomatous damage.Retrospective study conducted at Tohoku University Hospital.Thirty-eight eyes 19 patients with open-angle glaucoma.Patients were scanned T2-weighted and 3-T diffusion tensor imaging, parameters nerve, including fractional anisotropy, apparent coefficient cross-sectional area, determined. Conventional damage, circumpapillary macular retinal fibre layer...
Background and purposeRadiation-induced cerebral cavernous malformation reflects post-irradiation impairment of microcirculation. Our purpose was to determine effects radiation field size dose on the extent developing malformations in long-term survivors intracranial germ cell tumors (GCTs).MethodsThe study involved 34 patients with a history GCTs treated either whole-brain or reduced-field irradiation undergoing magnetic resonance (MR) imaging mean follow-up 18.5 years. The number...
Unilateral cerebral cortical encephalitis (UCCE) with myelin oligodendrocyte glycoprotein (MOG) antibody comprises a new spectrum of disease entities that are characterized by unilateral T2-weighted fluid-attenuated inversion recovery (T2 FLAIR) hyperintense lesions on MRI. In this retrospective study, the brain MRI 39 consecutive Japanese patients anti-MOG antibody-associated UCCE was examined. We found 37 (95%) also presented T2 FLAIR hypointensity in subcortical white matter adjacent to...
Background Hemimegalencephaly is a rare hamartomatous entity characterised by enlargement of all or part the cerebral hemisphere ipsilaterally with cortical dysgenesis, large lateral ventricle and white matter hypertrophy without advanced myelination. Although conventional magnetic resonance imaging (MRI) useful for detecting these diagnostic features, hemimegalencephaly not always easily distinguished from other entities, especially when shows blurring between grey matter. Diffusion tensor...
Summary: Purpose: To assess the biochemical properties of band heterotopia in comparison with other cortical developmental malformations (CDMs) by using proton magnetic resonance spectroscopy ( 1 H‐MRS). Methods: We performed localized single‐voxel H‐MRS studies on 13 patients [five (BH), two focal dysplasia (CD), unilateral CD, one bilateral perisylvian dysplasia, three hemimegalencephaly]. CDMs than BH were categorized as CD. Spectra acquired from volumes interest (VOIs) CD and...
ABSTRACT BACKGROUND AND PURPOSE Quantitative signal targeting with alternating radiofrequency labeling of arterial regions (QUASAR) is a recent spin technique that could improve the reliability brain perfusion measurements. Although it considered reliable for measuring gray matter as whole, has never been evaluated regionally. Here we assessed this regional reliability. METHODS Using 3‐Tesla Philips Achieva whole‐body system, scanned four times 10 healthy volunteers, in two sessions 2 weeks...
Background: Detailed investigations of the stapedial muscle (SM) in congenital aural atresia (CAA) patients have yet to be adequately conducted.Objectives: To assess image variations mastoid segment facial nerve (FN) and SM CAA.Materials methods: A total nine comprising 9 ears with unilateral CAA were studied. The courses FN evaluated from basic point 1 mm intervals between portion FN, measured mean X Y values each group.Results: side among showed significant differences compared...
Abstract Background The usefulness of apparent diffusion coefficient (ADC) and diffusion‐weighted magnetic resonance imaging (DWI) in the detection malignant tumors has been reported. purpose this study is to clarify role ADC DWI for diagnosis skull base tumors. Methods A total 27 patients with head neck invasions undergoing surgery were enrolled study. Pathological findings dural invasion bone compared diagnostic imaging. Results Advanced techniques revealed that values regions pathological...