A5005333691- Traumatic Brain Injury and Neurovascular Disturbances
- Disaster Response and Management
- Vascular Malformations Diagnosis and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Fluid Dynamics and Heat Transfer
- Erosion and Abrasive Machining
- Traumatic Brain Injury Research
- Cerebrovascular and Carotid Artery Diseases
- Kidney Stones and Urolithiasis Treatments
- Moyamoya disease diagnosis and treatment
- Cerebrospinal fluid and hydrocephalus
- Cardiac Arrest and Resuscitation
- Intracerebral and Subarachnoid Hemorrhage Research
- Trauma and Emergency Care Studies
- Combustion and Detonation Processes
- Acute Ischemic Stroke Management
- Laser-Plasma Interactions and Diagnostics
- Laser Applications in Dentistry and Medicine
- Cell Image Analysis Techniques
- Spinal Fractures and Fixation Techniques
- 3D Printing in Biomedical Research
- Neuroscience and Neural Engineering
- Head and Neck Surgical Oncology
Tohoku University Hospital
2013-2024
Tohoku University
2014-2023
Sendai University
2014-2020
Nakanishi (Japan)
2020
Creative Research Enterprises (United States)
2016
Kohnan Hospital
1998-2014
Japan Association for the Advancement of Medical Equipment
2011
Epson Information Technology College
2011
Seiko Holdings (Japan)
2011
Sendai City Hospital
2007-2011
The advent of image-activated cell sorting and imaging-based picking has advanced our knowledge exploitation biological systems in the last decade. Unfortunately, they generally rely on fluorescent labeling for cellular phenotyping, an indirect measure molecular landscape cell, which critical limitations. Here we demonstrate Raman by directly probing chemically specific intracellular vibrations via ultrafast multicolor stimulated scattering (SRS) microscopy phenotyping. Specifically,...
The upgraded version of intelligent image-activated cell sorting (iIACS) has enabled higher-throughput and more sensitive image-based single live cells from heterogeneous populations.
Machine-learning-assisted identification of platelet aggregation in human blood with label-free images.
Abstract A totally soft organic subdural electrode has been developed by embedding an array of poly(3,4-ethylenedioxythiophene)-modified carbon fabric (PEDOT-CF) into the polyvinyl alcohol (PVA) hydrogel substrate. The mesh structure stretchable PEDOT-CF allowed stable structural integration with PVA performance for monitoring electrocorticography (ECoG) was evaluated in saline solution, on ex vivo brains, and animal experiments using rats porcines. It demonstrated that large double-layer...
Object Shock waves have been experimentally applied to various neurosurgical treatments including fragmentation of cerebral emboli, perforation cyst walls or tissue, and delivery drugs into cells. Nevertheless, the application shock clinical neurosurgery remains challenging because threshold for wave–induced brain injury has not determined. The authors investigated pressure-dependent effect on histological changes rat brain, focusing especially apoptosis. Methods Adult male rats were exposed...
Intraventricular hemorrhage (IVH) on initial computed tomography (CT) was reported to predict lesions of diffuse axonal injury (DAI) in the corpus callosum (CC) subsequent magnetic resonance imaging (MRI). We aimed examine relationship between CT findings and DAI detected MRI as well severity IVH (IVH score) (DAI staging). A consecutive 140 patients with traumatic brain (TBI) who underwent within 30 days after onset were revisited. reviewed their for following six findings: Status basal...
<b>BACKGROUND AND PURPOSE:</b> High-attenuation areas (HDAs) called pseudo-subarachnoid hemorrhages (SAHs) may develop in some patients resuscitated from cardiopulmonary arrest (CPA), though no hemorrhage has occurred. We investigated the imaging characteristics and clinical significance of this phenomenon. <b>MATERIALS METHODS:</b> CT images consecutive nontraumatic CPA were reviewed classified into cases with pseudo-SAH (pseudo-SAH[+] group, <i>n</i> = 9), those without (pseudo-SAH[−] 28),...
A 9.0-magnitude earthquake occurred off the northeast coast of Japan at 2:46 p.m. (local time) on Friday, 11 March 2011, with epicenter approximately 70 km (43 mi) east Oshika Peninsula and hypocenter a depth 32 (20 below sea level [Figure 1(a)] [1]. The triggered powerful tsunami waves, which reached heights up to 40.5 m (133 ft) in Miyako traveled around 4 (about 2.5 inland Sendai area. As 30 2012, total 18,897 people were either dead or missing.
Surgical revascularization for moyamoya disease prevents cerebral ischemic attacks by improving blood flow (CBF). Symptomatic hyperperfusion is a potential complication of this procedure, but its treatment contradictory to that ischemia. Because intraoperative techniques detect are still lacking, the authors performed infrared monitoring in using novel imaging system.During superficial temporal artery-middle artery anastomosis 25 patients (26 hemispheres) with disease, monitored brain...
OBJECTIVEThe objective of this study was to test the hypothesis that midline (interhemispheric or perimesencephalic) traumatic subarachnoid hemorrhage (tSAH) on initial CT may implicate same shearing mechanism underlies severe diffuse axonal injury (DAI).METHODSThe authors enrolled 270 consecutive patients (mean age [± SD] 43 ± 23.3 years) with a history head trauma who had undergone within 24 hours and brain MRI 30 days. Six findings, including intraventricular (IVH) tSAH, were used as...
An intrinsically soft organic electrode consisting of poly(3,4-ethylenedioxythiophene)-modified polyurethane (PEDOT-PU) is embedded into a bilayer film polyvinyl alcohol (PVA) hydrogels for developing self-closing cuff neuromodulation. The curled form the PVA hydrogel prepared by releasing internal stress in structure. inner diameter set to less than 2 mm immobilization vagus nerve (VN) humans and pigs. stability examined, while pressure applied bundle at harmless level (≈200 Pa). Since...
We compared Canadian computed tomography (CT) head rule (CCHR) and New Orleans Criteria (NOC) in predicting important CT findings patients with mild traumatic brain injury (TBI). included 142 consecutive TBI [Glasgow coma scale (GCS) 13–15] who showed at least one of the risk factors stated CCHR or NOC. introduced two scores: a from A patient's score represented sum number positive items. examined relationship between scores items presence findings. Only was significantly associated...
The "wearing-off" phenomenon often hampers the treatment of Parkinson disease (PD). Although deep brain stimulation (DBS) subthalamic nucleus (STN) is known to ameliorate wearing-off phenomenon, mechanism by which it does this remains unclear. As part an inquiry into STN DBS, authors measured synaptic dopamine levels in striatum performing positron emission tomography (PET) with [11C]raclopride.Three patients PD who were experiencing underwent PET scanning before and after DBS STN. clinical...
This paper reports characteristics of an actuator-driven pulsed water jet generator applied, in particular, to dissect soft tissues. Results experiments, by making use high speed recording optical visualization and varying nozzle diameter, actuator time interval, their effects on dissection performance are presented. Jet penetration compared with continuous hence potential assessment jets clinical applications is performed.
Abstract Background and Objectives Although water jet technology has been considered as a feasible neuroendoscopic dissection methodology because of its ability to perform selective tissue without thermal damage, problems associated with continuous use the ensuing fountain‐effect—with catapulting tissue—could make jets unsuitable for endoscopic use, in terms safety ease handling. Therefore, authors experimented minimization usage during application pulsed holmium:yttrium‐aluminum‐garnet...
Paroxysmal sympathetic hyperactivity (PSH) is a distinct syndrome of episodic hyperactivities following severe acquired brain injury, characterized by paroxysmal transient fever, tachycardia, hypertension, tachypnea, excessive diaphoresis and specific posturing. PSH remains to be an under-recognized condition with diagnostic pitfall especially in the intensive care unit (ICU) settings due high prevalence concomitant diseases that mimic PSH. A consensus set criteria named PSH-Assessment...
<b><i>Background/Purpose:</i></b> The water jet technique dissects tissue while sparing cord-like structures such as blood vessels. mechanism of tissue-selective dissection has been unknown. novel piezo actuator-driven pulsed (ADPJ) system can achieve with remarkably reduced consumption compared to the conventional jet; however, system's characteristics and capabilities on any organ have not clarified. purposes this study were characterize physical properties ADPJ...