A5036808038- 3D Shape Modeling and Analysis
- RNA and protein synthesis mechanisms
- Computer Graphics and Visualization Techniques
- Advanced Vision and Imaging
- Bioinformatics and Genomic Networks
- Genetics, Bioinformatics, and Biomedical Research
- Gene expression and cancer classification
- Lipid metabolism and biosynthesis
- Wound Healing and Treatments
- Machine Learning in Bioinformatics
- Biomedical Text Mining and Ontologies
- Sepsis Diagnosis and Treatment
- Biodiesel Production and Applications
- Biochemical and Structural Characterization
- Microbial Metabolic Engineering and Bioproduction
- thermodynamics and calorimetric analyses
- vaccines and immunoinformatics approaches
- Plant biochemistry and biosynthesis
- Human Motion and Animation
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Periodontal Regeneration and Treatments
- Genetically Modified Organisms Research
- Robotics and Sensor-Based Localization
- Mesenchymal stem cell research
University of Petroleum and Energy Studies
2025
Temasek Life Sciences Laboratory
2011-2025
National University of Singapore
2011-2025
Institute of Genomics and Integrative Biology
2004-2021
École de Technologie Supérieure
2018-2021
Council of Scientific and Industrial Research
2004-2021
Academy of Scientific and Innovative Research
2016
Aptamers, the chemical-antibody substitute to conventional antibodies, are primarily discovered through SELEX technology involving multi-round selections and enrichment. Circumventing methodology, here we report an in silico selection of aptamers estrogen receptor alpha (ERα) using RNA analogs human response elements (EREs). The inverted repeat nature ERE ability form stable hairpins were used as criteria obtain aptamer-alike sequences. Near-native selected single stranded EREs modelled...
Abstract Motivation: The adhesion of microbial pathogens to host cells is mediated by adhesins. Experimental methods used for characterizing adhesins are time-consuming and demand large resources. availability specialized software can rapidly aid experimenters in simplifying this problem. We have employed 105 compositional properties artificial neural networks develop SPAAN, which predicts the probability a protein being an adhesin (Pad). Results: SPAAN had optimal sensitivity 89%...
GM Jatropha X8#34 was placed for transgene flow assessment in the open field trial on Semakau Island, Singapore, between 2015 and 2017 to evaluate potential gene its non-GM counterparts related species. The featured event X8#34, which is characterized by high oleic acid content, marker-free, a homozygous transgene. study focused cross-pollination from plants, analyzing factors such as distance, wind insects mediated transfer, using event-specific multiplex PCR analysis of F1 seeds. Pollen...
One key reason for the failure of Jatropha plantation is use non-improved planting materials. We present in this paper a variety (JO S2) through selective breeding with much better seed productivity than wild accessions as proven by field trials Singapore and India. In single farm trial two years, comparison was conducted from China, India, Indonesia Africa. It found that all traits studied like yield, kernel content, oil fatty acid composition, phosphorus content PE differed significantly...
Monitoring respiratory parameters is essential in pediatric intensive care units (PICUs), yet bedside tidal volume (Vt) measurement rarely performed due to the need for invasive airflow sensors. We present a real-time, non-contact monitoring system using Azure Kinect DK (Microsoft, Redmond, WA, USA) depth camera, specifically designed use PICU. The automatically tracks thoracic variations derive comprehensive set of ventilator equivalent parameters: volume, rate, minute ventilation,...
Delayed wound healing is a major complication associated with diabetes and result of complex interplay among diverse deregulated cellular parameters. Although several genes pathways have been identified to be mediating impaired closure, the role microRNAs (miRNAs) in these events not very well understood. Here, we identify an altered miRNA signature prolonged inflammatory phase during diabetes, increased infiltration cells basal layer epidermis. Nineteen miRNAs were downregulated diabetic...
Abstract We present a general method for transferring skeletons and skinning weights between characters with distinct mesh topologies. Our pipeline takes as inputs source character rig (consisting of mesh, transformation hierarchy joints, weights) target mesh. From these inputs, we compute joint locations orientations that embed the skeleton in well to bind geometry new skeleton. consists two key steps. first geometric correspondence meshes using semi‐automatic relying on set markers. The...
Abstract We propose the first approach that can generate procedural three‐dimensional (3D) hair involving braids modeled from a single‐view photograph. Existing image‐based modeling methods fail to handle braided hairstyles. Our combines image processing, deep neural networks, as well two‐dimensional (2D) and 3D geometric algorithms. In order train our network, we create braid unit data set. recognition segmentation system successfully segment regions, non‐braid using convolutional networks....
Abstract Background Microarray is a high-throughput technology to study expression of thousands genes in parallel. A critical aspect microarray production the design aimed at space optimization while maximizing number gene probes and their replicates be spotted. Results We have developed software called 'ArrayD' that offers various alternative solutions for an array given set user requirements. The feeds following inputs: type source plates used, printed, pins used printing. are stored text...
The rhizosphere microbiomes of rice plants consist a complex consortium methanogens, methanotrophs, nitrogen- and/or sulphur-assimilating microorganisms. Controlled irrigation has been purported to be the cultivation method choice over continuous flooding as it reduces water usage and aerates soil minimize emission potent greenhouse gases. However, systemic understanding assembly function microbiota in under drip flood remains unclear. Here, we report significant reduction methane emissions...