A5100650000- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Obesity, Physical Activity, Diet
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Respiratory and Cough-Related Research
- Nutritional Studies and Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Exercise and Physiological Responses
- Dermatology and Skin Diseases
- Medication Adherence and Compliance
- Healthcare Regulation
- Microfinance and Financial Inclusion
- Nutrition and Health in Aging
- Health and Lifestyle Studies
- Mobile Health and mHealth Applications
- Noise Effects and Management
- Child Nutrition and Feeding Issues
- Urticaria and Related Conditions
- Child and Adolescent Health
- Advanced Chemical Sensor Technologies
- Inhalation and Respiratory Drug Delivery
- Clinical Nutrition and Gastroenterology
- Renal function and acid-base balance
- Eating Disorders and Behaviors
Universidade do Porto
2016-2025
Hospital de São João
2016-2025
Polytechnic Institute of Porto
2024
Centre universitaire de médecine générale et santé publique, Lausanne
2024
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2024
Fundación Valle del Lili
2024
Sociedade Portuguesa de Cardiologia
2017-2023
Hospital Beatriz Ângelo
2023
Translational Research in Oncology
2023
Hospital da Luz
2023
Indoor air contaminants may act as endocrine-disrupting chemicals (EDCs). However, to what extent these affect health is poorly known. We aimed assess the association between EDCs exposure and asthma, respiratory symptoms obesity in schoolchildren.Data from a cross-sectional analysis of 815 participants 20 schools Porto, Portugal, were analysed. Symptoms assessed, asthma was defined on lung function, airway reversibility body mass index (BMI) calculated. The concentrations 13 volatile...
A novel approach is described using chitosan–genipin films as a sustainable method for wine preservation.
Introduction: Clusters of asthma in athletes have been insufficiently studied. Therefore, the present study aimed to characterize phenotypes elite using latent class analysis (LCA) and evaluate its association with type sport practiced. Methods: In cross-sectional study, an athletes’ records was carried out databases Portuguese National Anti-Doping Committee Norwegian School Sport Sciences. Athletes asthma, diagnosed according criteria given by International Olympic Committee, were included...
Abstract Background Childhood exposure to microbiologic agents may influence the development of allergic and respiratory diseases. Apart from home, children spend most their time at school, which represents an environment significant indoor air microbes. Therefore, we aimed assess how prevalence sensitization asthma in schoolchildren is affected by within classrooms. Methods Spirometry with bronchodilation, exhaled nitric oxide measurements skin‐prick tests data were retrieved 858 aged 8–10...
Abstract Background The diagnosis and phenotyping of paediatric asthma are particularly complex due to the lack currently available sensitive diagnostic tools. This often results in uncertainties associated with inhaled steroid therapy prescription. Therefore, this study aimed investigate whether volatile organic compounds measured exhaled breath condensate can be used as biomarkers for population. Methods A total 64 participants, aged 6‐18 years, were recruited on a random basis during...
Detection and quantification of microRNAs (miRNAs) in exhaled breath condensate (EBC) has been poorly explored. Therefore we aimed to assess miRNAs EBC as potential biomarkers diagnose endotype asthma school aged children. In a cross sectional, nested case control study, all the asthmatic children (n = 71) random sample controls 115), 7 12 years, attending 71 classrooms from 20 local schools were selected arbitrarily allocated development or validation set. Participants underwent skin-prick...
Abstract Children are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of environment walkability surrounding schools on lung function, airway inflammation autonomic nervous system activity. Data 701 children from 20 primary were analysed. Lung pH exhaled breath condensate measured. Pupillometry was performed evaluate Land use composition index quantified within a 500 m buffer zone around schools. The...
Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler needed. The InspirerMundi app aims to monitor while providing positive experience through gamification social support.
Background Atopic dermatitis (AD) patients may benefit from using textiles coated with skin microbiome–modulating compounds. Chitosan, a natural biopolymer immunomodulatory and antimicrobial properties, has been considered potentially useful. Objective This randomized controlled trial assessed the clinical utility of chitosan-coated garment use in AD. Methods Of 102 screened, 78 adult adolescents were randomly allocated to overnight or uncoated cotton long-sleeved pyjama tops pants for 8...
Inhalation of fine particulate matter (PM) can cause systematic inflammation and oxidative stress, which may further aggravate the development progression asthma. Although nutritional intake fatty acids antioxidants attenuate some effects PM, role inflammatory potential diet has not been addressed. Therefore, we aimed to investigate possible modulatory dietary on association between indoor air pollution childhood asthma-related outcomes.In a sample 501 children (48.1% females, aged 7-12...
Abstract Background A diet rich in fruits and vegetables has been suggested to counteract the oxidative stress inflammation that characterize asthma. We aimed assess association between vegetable fruit diversity consumption asthma its related outcomes school‐aged children. Methods Participants included 647 children (49% females, aged 7‐12 years) recruited from 20 public schools across city of Porto, Portugal. Vegetable intake were ascertained using a single self‐reported 24‐hour recall...
Abstract Allergic asthma (AA) is a common phenotype, and its diagnosis requires both the demonstration of IgE‐sensitization to aeroallergens causative role this sensitization as major driver symptoms. Therefore, bronchial allergen challenge (BAC) would be occasionally required identify AA patients among atopic asthmatics. Nevertheless, BAC usually considered research tool only, with existing protocols being tailored mild asthmatics needs (eg long washout period for inhaled corticosteroids)....
This study aimed to assess the acute effects of two isoenergetic but micronutrient-diverse meals—a Mediterranean-like meal (MdM) and a fast food-like (FFM)—on autonomic nervous system (ANS), lung function, airway inflammation response. Forty-six participants were enrolled in randomized cross-over clinical trial, consuming meals: FFM (burger, fries, sugar-sweetened drink) MdM (vegetable soup, whole wheat pasta, salad, olive oil, sardines, fruit, water). Pupillometry...
A microangiopatia trombótica (MAT) é uma manifestação sindrômica rara marcada por anemia hemolítica microangiopática, trombocitopenia e microtrombos, podendo afetar diversos órgãos, frequentemente os rins, sua extensa complexa rede microvascular. Diversas são as etiologias que podem culminar nessa apresentação, dentre elas, a esclerose sistêmica, doença autoimune do tecido conjuntivo resulta em fibrose sistêmica difusa, pode evoluir com acometimento renal. MAT na (MAT-ES) consequência da...
This study aimed to assess the acute effects of two isoenergetic but micronutrient-diverse meals-a Mediterranean-like meal (MdM) and a fast food-like (FFM)-on autonomic nervous system (ANS), lung function, airway inflammation response. Forty-six participants were enrolled in randomized crossover clinical trial, consuming meals: FFM (burger, fries, sugar-sweetened drink) MdM (vegetable soup, whole-wheat pasta, salad, olive oil, sardines, fruit, water). Pupillometry assessed parasympathetic...
Background: Handgrip strength (HGS) is a useful indicator of nutrition status in adults, but evidence lacking pediatric patients. The aim this study was to describe the association between undernutrition and HGS patients at hospital admission, quantifying modifying effect disease severity, anthropometrics, other patient characteristics on HGS. Materials Methods : Eighty‐nine inpatients aged ≥6 years consecutively admitted were recruited longitudinal study. Nutrition evaluated using body mass...
The majority of drugs prescribed have not been tested in children and safety efficacy children's medicines are frequently supported by low quality evidence. Therefore, a large percentage prescriptions for the clinical daily practice used off label. Despite several recent legislation regulatory efforts performed worldwide, they successful increasing availability adapted to children. Moreover, if we consider that 30% respiratory field only 4% new investigation projects research were proposed...
We aimed to compare patient's and physician's ratings of inhaled medication adherence identify predictors patient-physician discordance. Baseline data from two prospective multicentre observational studies. 29 allergy, pulmonology paediatric secondary care outpatient clinics in Portugal. 395 patients (≥13 years old) with persistent asthma. Data on demographics, relationship, upper airway control, asthma treatment, forced expiratory volume one second (FEV1) healthcare use were collected....
Abstract We hypothesize that oxidative stress induced by trichloramine exposure during swimming could be related to etiopathogenesis of asthma among elite swimmers. Aim To investigate the effect a training session on markers asthmatic compared non‐asthmatic swimmers using exhaled breath ( EB ) metabolomics. Methods Elite annually screened in our department (n=27) were invited and those who agreed participate (n=20, which 9 with asthma) had collected (Tedlar ® bags) before after session. SPME...
Abstract Background The definitions of childhood asthma differ among epidemiological studies. We aimed to compare the diagnostic accuracy and agreement previous evaluate questionnaire‐driven definition patterns. Methods Data on 808 participants aged 7‐12 years from 20 schools were analyzed. Asthma based symptoms assessed by questionnaire, parent‐reported medical diagnosis, current use medication, airway reversibility after bronchodilatation, increased (≥35 ppb) levels exhaled nitric oxide...