A5100438445- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- Colorectal Cancer Screening and Detection
- Advanced Radiotherapy Techniques
- Posttraumatic Stress Disorder Research
- Genetic factors in colorectal cancer
- Acute Myeloid Leukemia Research
- Anorectal Disease Treatments and Outcomes
- Acute Lymphoblastic Leukemia research
- Lymphoma Diagnosis and Treatment
- COVID-19 and Mental Health
- Microscopic Colitis
- Dementia and Cognitive Impairment Research
- Immune cells in cancer
- Innovative Educational Techniques
- Statistical Methods in Clinical Trials
- Acute Kidney Injury Research
- Endometrial and Cervical Cancer Treatments
- Inflammatory Biomarkers in Disease Prognosis
Zunyi Medical University
2025
First Hospital of China Medical University
2024
China Medical University
2024
Biogen (United States)
2023
Second Military Medical University
2020-2023
Changhai Hospital
2020-2023
Sichuan University
2021-2023
Hansoh Pharma (China)
2023
Huazhong University of Science and Technology
2023
Tongji Hospital
2023
Abstract Background The outbreak of Coronavirus Disease 2019(COVID-19) caused psychological stress in Chinese adults population. But we are unaware whether the pandemic causes on children. Methods We used Children’s Impact Event Scale questionnaire (CRIES-13) to investigate degree Post-traumatic Stress (PTSD) symptoms by students selected from schools Sichuan, Jiangsu, Henan, Yunnan, and Chongqing provinces China. Results A total 7769 students(3692 male 4077 female), aged 8–18 years, were...
Background . The prognostic value of tumor deposit (TD) count in colorectal cancer (CRC) patients has been rarely evaluated. This study is aimed at exploring the TD and finding out optimal cutoff point to differentiate prognoses TD-positive CRC patients. Method Patients diagnosed with from Surveillance, Epidemiology, End Results (SEER) database January 1, 2010, December 31, 2012, were analyzed. X-tile program was used identify training cohort, a validation cohort test this after propensity...
Whether adjuvant chemotherapy is beneficial for rectal cancer patients who respond well to neoadjuvant chemoradiotherapy (NCRT) and undergo radical resection controversial. This study aimed assess the effect of on oncological outcomes ypT0-2N0 after NCRT resection, identify prognostic factors.The clinical pathological data with underwent between January, 2010 June, 2018 were collected retrospectively analyzed. The (chemo) group non-chemotherapy (non-chemo) compared. Multivariate analysis,...
Background: Aumolertinib (HS-10296), a 3rd-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), has been shown to have efficacy in treating tumors harboring EGFR sensitive mutations: in-frame deletions or insertions within exon 19 deletion (19Del) and the 21 L858R mutation T790M resistance mutation. Research that tumor protein p53 (TP53) mutations leptomeningeal metastases (LM) are associated with reduced responsiveness poor prognosis patients advanced...
Acute kidney injury (AKI) is a common and severe complication in patients with cirrhosis, associated poor prognosis. Therefore, identifying cirrhotic AKI who are at high risk of mortality very important may be helpful for providing timely medical interventions to improve the prognosis these patients. However, studies focused on investigating factors were scarce.To identify establish nomogram predicting patients.Two hundred fifty consecutive cirrhosis recruited randomly divided into training...
The safe distance between the intraoperative resection line and visible margin of distal rectal tumor after preoperative radiotherapy is unclear. We aimed to investigate furthest intramural spread in fresh tissue determine a length.Twenty cancer specimens were collected radiotherapy. Tumor distances defined as tumor's microscopic margins. Visible margins identified during operation labeled with 5 - 0 sutures under naked eye at 5, 6, 7 o'clock directions immediately removal tumor. After...
Abstract Background There are only a few studies on the prognosis of patients with complete response tumour (ypT0) after neoadjuvant chemoradiotherapy (NCRT) and radical resection rectal cancer. The aim study was to identify prognostic factors regard oncological outcome in ypT0 NCRT resection. Methods All cancer between January 2010 June 2019 were included. Cox univariate multivariate regression analyses used determine these patients. Results Seventy‐six In nine (11.8%), lymph node...
Hemoclips have been used to protect leakage after endoscopic resection of large colorectal polyps or early-staged rectal cancer, for perforation the sigmoid colon during colonoscopy. However, clips were seldom manage anastomotic low anterior cancer. A patient with postoperative cancer was successfully treated by hemoclips under colonoscopic vision failure conservative treatment. Postoperative course uncomplicated and discharged from hospital seven days later. Endoscopic should be considered...
The optimal strategy for maintenance therapy in patients with metastatic colorectal cancer (mCRC) remains controversial. Considering that, beyond progression, co-therapy bevacizumab and cytotoxic chemotherapy showed less toxicity a significant disease control rate. We aimed to investigate the differences efficacy safety between combined capecitabine monotherapy RAS-mutant mCRC （as defined by mutations KRAS NRAS exons 2-4）controlled plus FOLFIRI at least 12 weeks.We retrospectively analysed...
Radiotherapy is one of the main treatments for cervical cancer. Long-term complications radiation exposure include emergence secondary tumors. This a retrospective study based on an American population. We discuss optimal treatment modality patients with radiation-induced uterine malignancy Surveillance, Epidemiology, and End Results database. The included definitive pathological diagnosis cancer who were diagnosed malignant tumor ≥ 1 year later. Patients in whom was not first or missing...
Abstract JN.1 is a subvariant of SARS-CoV-2 Omicron BA.2.86 lineage that was predominant worldwide in early 2024, which the vivo characteristics are largely unknown. Our results demonstrated replication more efficient than parental BA.2 Vero cells, low dependence on TMPRSS2. Compared to variants and XBB EG.5.1, replicated less efficiently hACE2 mouse lungs intranasal infection not lethal mice led weaker immune dysregulation. On sensitive, aged hamster model, lower mortality rate no weight...
Abstract Background : The outbreak of Coronavirus Disease 2019(COVID-19) caused psychological stress in Chinese adults population. But we are unaware whether the pandemic causes on children. Methods: We used Children’s Impact Event Scale questionnaire (CRIES-13) to investigate degree Post-traumatic Stress (PTSD) symptoms by students selected from schools Sichuan, Jiangsu, Henan, Yunnan, and Chongqing provinces China. Results: A total 7769 students(3692 male 4077 female), aged 8-18 years,...
The prognosis of patients with peripheral T-cell (PTCL) or lymphoblastic lymphoma (T-LBL) remains poor under current conditioning regimens before receiving autologous stem cell transplantation (ASCT).Patients PTCL T-LBL were enrolled to receive ASCT using the regimen chidamide, cladribine, gemcitabine, and busulfan (ChiCGB). Positron emission tomography-computed tomography (PET/CT) was used evaluate response ASCT. Overall survival (OS) progression-free (PFS) employed assess patient outcome,...
Background Myelodysplastic syndromes (MDS) encompass a group of heterogeneous haematopoietic stem cell malignancies characterised by ineffective haematopoiesis, cytological aberrations, and propensity for progression to acute myeloid leukaemia. Diagnosis disease prognostic stratification are much based on genomic abnormalities. The traditional metaphase cytogenetics analysis (MC) can detect about 40–60% aberrations. Single-nucleotide polymorphism arrays (SNP-A) karyotyping copy number...
Abstract Background A previous comparative analysis of plasma Aβ42/40 immunoassays and mass spectrometry‐based assays conducted in 2021 found that several had strong performance predicting amyloid PET status (Zicha et al., 2022). In the spirit enabling National Institute on Aging Alzheimer’s Association framework for classifying disease (AD) utilizing measures pathology amyloid, tau, neurodegeneration (ATN), we have added to this a newly developed immunoassay an automated, scalable platform....