A5100325741- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Anesthesia and Pain Management
- Nausea and vomiting management
- Global Maternal and Child Health
- Pregnancy and preeclampsia studies
- Injury Epidemiology and Prevention
- Complementary and Alternative Medicine Studies
- Myofascial pain diagnosis and treatment
- Birth, Development, and Health
- Global Healthcare and Medical Tourism
- Pregnancy and Medication Impact
- Testicular diseases and treatments
- Dementia and Cognitive Impairment Research
- Psychosomatic Disorders and Their Treatments
- Congenital Anomalies and Fetal Surgery
- Medical Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Child Nutrition and Water Access
- Mesenchymal stem cell research
- Maternal Mental Health During Pregnancy and Postpartum
- Menstrual Health and Disorders
- Liver Disease Diagnosis and Treatment
- Pediatric health and respiratory diseases
Shanghai University of Traditional Chinese Medicine
2022-2025
Sichuan University
2012-2025
West China Second University Hospital of Sichuan University
2011-2025
Harbin Medical University
2021-2025
Shandong Agricultural University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2025
Jiaxing University
2018-2025
Affiliated Hospital of Jining Medical University
2024-2025
Weatherford College
2011-2024
Zhejiang Marine Fisheries Research Institute
2024
Copper deficiency has emerged to be associated with various lipid metabolism diseases, including non-alcoholic fatty liver disease (NAFLD). However, the mechanisms that dictate association between copper and metabolic diseases remain obscure. Here, we reveal restoration caused by hepatic ceruloplasmin (Cp) ablation enhances catabolism promoting assembly of copper-load SCO1-LKB1-AMPK complex. Overnutrition-mediated Cp elevation results in loss, whereas restores content normal level without...
Gestational diabetes mellitus (GDM), a severe pregnancy disorder, is temporary form of that occurs during gestation. Astragaloside IV (AS IV), natural and effective composition Astragalus membranaceus, shows pharmacological effects against diabetes. On the contrary, AS on GDM development are still not clear. This study aims to investigate role in alleviating rats determine whether exerts its anti-GDM properties through regulation gut microbiota metabolite modulation. There were six pregnant...
Increase of blood brain barrier (BBB) permeability after acute ischemia stroke is a predictor to intracerebral hemorrhage transformation for tissue plasminogen activator (tPA) thrombolysis and post-endovascular treatment. Previous studies showed that 2-h induced damage BBB integrity matrix metalloproteinase-2 (MMP-2) made major contribution this disruption. A recent study blocking β2-adrenergic receptor (β2-AR) alleviated ischemia-induced injury by reducing hypoxia-inducible factor-1 alpha...
Facing considerable challenges associated with aging and dementia, China urgently needs an evidence-based health-care system for prevention management of dementia. The Beijing Aging Brain Rejuvenation Initiative (BABRI) is a community-based cohort study initiated in 2008 that focuses on asymptomatic stages aims to develop strategies cognitive impairment, provides platform scientific research clinical trials. Thus far, BABRI has recruited 10,255 participants (aged 50 over, 60.3% female), 2021...
Abstract FR901464, a natural product isolated from bacterium source, activates reporter gene, inhibits pre‐mRNA splicing, and shows antitumor activity. We previously reported the development of more potent analogue, meayamycin, through total synthesis FR901464. Herein, we report detailed structure–activity relationships FR901464 that revealed significance epoxide, carbon atoms in tetrahydropyran ring, Z geometry side chain, 1,3‐diene moiety, C4‐hydroxy group, C2′′‐carbonyl group....
Objectives The aim of this study was to explore the current situation kinesiophobia in patients with coronary heart disease, classify it based on potential profile analysis and relevant factors different categories disease. Design Cross-sectional study. Setting Patients disease China. Participants Adult (aged >18 years) China; 252 participants answered questionnaire. Primary secondary outcome measures investigated scores Tampa Scale for Kinesiophobia Heart, collected information patient’s...
Abstract Objective This study aimed to evaluate the performance of noninvasive prenatal testing (NIPT) for detecting three common trisomies (T21, T18, and T13) in pregnant women with diverse clinical indications. Methods Frequencies NIPT, high chance having one trisomies, confirmed were determined each seven indications a national cross‐sectional survey approximately 300 diagnosis centers. Data collected period from October 1, 2016 September 30, 2018 using Prenatal Diagnosis Technology...
Drug exposure during pregnancy lacks global fetal safety data. The maternal drug birth cohort (DEBC) study, a prospective longitudinal investigation, aims to explore the correlation of with outcomes, and establish human biospecimen biobank. Here we describe process establishing DEBC show that rate in first trimester pregnant women (n = 112,986) is 30.70%. Among drugs used, dydrogesterone progesterone have highest rates, which are 11.97% 10.82%, respectively. overall incidence adverse...
Background: Although several studies have documented a higher prevalence of psychiatric disorders in children depressed than nondepressed parents, previous research was conducted predominantly White, middle, or upper-middle class populations. Only limited information is available on and psychosocial functioning low-income mothers. Methods: We report the findings mothers with without lifetime history major depressive disorder, who were recruited from large urban primary-care practice....
Background: Traditional Chinese Medicine (TCM) JingYinGuBiao formula (JYGB) was recommended by the Expert consensus on diagnosis and treatment of COVID-19 infection in Shanghai.We evaluated safety efficacy JYGB treating mild patients.Methods: A prospective, double-blind, randomized, controlled trial conducted (ClinicalTrial.govregistration number: ChiCTR2200058695).A total 885 patients were randomized into group (administration JYGB,n=508) or control TCM placebo, n=377) with 7-day...
Abstract Integrated traditional Chinese medicine (TCM) and Western (WM) is a new medical science grounded in the knowledge bases of both TCM WM, which then forms unique modern system China. WM has long history China, made important achievements process clinical diagnosis treatment. However, methodological defects currently published practice guidelines limit its development. The organic integration deeper WM. To realize progression "integration" to "organic integration", targeted...
Thoracic paravertebral block offers effective analgesia after laparoscopic nephrectomy but has potential severe complication risks. Erector spinae plane been described for abdominal surgery. However, there are no prospective randomized trials determining if ultrasound-guided erector is non-inferior to thoracic in terms of surgeries including nephrectomy.Sixty-six patients scheduled were a 1:1 ratio receive (erector group) or (thoracic with 25 mL 0.5% ropivacaine. The primary outcome this...
It has been reported that the nervous system can regulate immune reactions through various mechanisms. However, role of splenic sympathetic nerve activity in autoimmune during pathogenesis experimental encephalomyelitis (EAE) remained unclear. Here, we blocked and found number adaptive cells, such as CD4+ T CD8+ cells B were upregulated. Additionally, there was an increase secretion inflammatory cytokines spleen, neurological symptoms EAE exacerbated. In vitro experiments, norepinephrine...
Seasonality in the incidence of congenital hypothyroidism (CH) has been identified several countries and different conclusions have drawn. The objective this study was to examine whether seasonality is also observable China how it manifests across temperate zones. Data on CH cases screened neonates between January 1, 2014, September 30, 2022, by year season, were sourced from Chinese Newborn Screening Information System. overall zones analyzed using seasonal unit root test, decomposition,...