A5101624085- Bone fractures and treatments
- Respiratory viral infections research
- Influenza Virus Research Studies
- Cancer Cells and Metastasis
- Lung Cancer Research Studies
- Computational Drug Discovery Methods
- Diabetes and associated disorders
- Cancer Mechanisms and Therapy
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Total Knee Arthroplasty Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Cholinesterase and Neurodegenerative Diseases
- Spinal Fractures and Fixation Techniques
- Spinal Cord Injury Research
- Orthopedic Surgery and Rehabilitation
- Immune Cell Function and Interaction
- Knee injuries and reconstruction techniques
- Cancer-related Molecular Pathways
- Cervical and Thoracic Myelopathy
- Environmental DNA in Biodiversity Studies
- Gestational Diabetes Research and Management
- Machine Learning in Bioinformatics
- Immune cells in cancer
- Connective tissue disorders research
First Affiliated Hospital of Dalian Medical University
2012-2025
Dalian Medical University
2012-2025
Third Affiliated Hospital of Zhengzhou University
2025
General Hospital of Shenyang Military Region
2020-2025
Qilu Hospital of Shandong University
2024
Hengshui University
2022
First Affiliated Hospital of Bengbu Medical College
2020-2022
Yangzhou University
2021
Northern Jiangsu People's Hospital
2021
Harbin Veterinary Research Institute
2016-2019
Sox2 and Oct4 are transcription factors with the characteristics of regulating self-renewal differentiation embryonic stem cell. The aim this study was to detect expression analyze their clinical significance in human non-small-cell lung cancer (NSCLC). Expression were assayed tissues corresponding paracancerous from 44 patients NSCLC 21 benign tumors using immunohistochemistry, Western blot, reverse polymerase chain reaction (RT-PCR). correlation between tumor type, grade prognosis utility...
The emergence of the PB2 E627K substitution is critical in mammalian adaptation and pathogenesis AIV. H7N9 AIVs that emerged 2013 possess a prominent ability gaining mutation humans. Here, we demonstrate acquisition driven by low polymerase activity conferred viral PA protein human cells, four residues are collectively involved this process. Notably, leads to significant dependence function on ANP32A protein, Anp32a knockout abolishes mice. These findings reveal host crucial for during
Thyroid parameters undergo significant dynamic changes during pregnancy. This study aimed to comprehensively analyze the impact of abnormal thyroid in each trimester on incidence common adverse obstetric outcomes. Blood samples drawn for antenatal period were determined after participants gave birth. Serum thyrotropin, free thyroxine, triiodothyronine, anti-thyroid peroxidase antibody (TPOAb), and anti-thyroglobulin (TgAb) levels tested using electrochemiluminescence immunoassays. Among all...
Influenza A virus (IAV) matrix protein 2 (M2) plays multiple roles in the early and late phases of viral infection. Once synthesized, M2 is translocated to endoplasmic reticulum (ER), travels Golgi apparatus, sorted at trans-Golgi network (TGN) for transport apical plasma membrane, where it functions budding. We hypothesized that trafficking along with its secretory pathway must be finely regulated, host factors could involved this process. However, no studies examining role...
Introduction During sedation for gastroscopy, hypoxaemia represents the most common adverse event. The objective of this trial is to assess efficacy and safety bilevel positive airway pressure (BPAP) prevention hypoxaemia, in comparison with nasal cannula oxygen therapy, among patients predisposed during gastroscopy. Methods analysis This randomised controlled (RCT) will include 616 at risk when undergoing including those advanced age, frailty, American Society Anesthesiologists grades...
Lung cancer is the third most frequent human malignant tumour and leading cause of cancer‑associated mortality worldwide. Emerging lines evidence have demonstrated that microRNAs (miRNAs) are upregulated or downregulated in non‑small cell lung (NSCLC), this phenomenon involved regulation various processes during tumorigenesis progression, including groWTh, apoptosis, invasion, metastasis. Therefore, understanding molecular mechanism associates abnormally expressed miRNAs with NSCLC formation...
Bilateral synchronous multiple primary lung adenocarcinoma (BSMPLA) is a rapidly increasing disease for which timely and accurate treatment required. We describe our experience we hope to establish optimal therapeutic options patients with BSMPLA.This study aimed explore the feasibility safety of simultaneous bilateral video-assisted thoracoscopic surgery (VATS) in 56 who received histological diagnoses BSMPLA at hospital between January 2016 2018. In this retrospective analysis clinical...
Patients with the luminal B subtype of breast cancer exhibit a poor prognosis, high metastatic risk and incidence chemotherapy resistance. Luminal is sub-classified into B1 B2. The pathophysiological mechanism B2 (LB2BC) progression has yet to be characterized. Therefore, present study aimed identify genes involved in pathogenesis LB2BC. data 117 LB2BC expression profiles were downloaded from Cancer Genome Atlas (TCGA) differentially expressed (DEGs) identified by comparison non-tumor tissue...
Vaginal delivery is the ideal mode of for termination a pregnancy. However, cesarean section rate in China much higher than published by World Health Organization Lancet 2010.To retrospectively analyze factors related to failed trial labor and clinical indications conversion, explore how promote success rate, determine feasibility reducing conversion section.A retrospective analysis was performed on 9240 maternal women who met vaginal conditions required from January 2016 December 2018 at...
AIM:To evaluate the association of β-2 adrenergic receptor (β2-AR ) gene polymorphism with response variceal pressure to propranolol in cirrhosis. METHODS:Sixty-four non-related cirrhotic patients participated this study and accepted measurement before after administration.Polymorphism β2-AR was determined by directly sequencing polymerase chain reaction products from DNA samples that were prepared patients. RESULTS:The prevalence Gly16-Glu/Gln27 Arg16-Gln27 homozygotes, compound...
To summarize the surgical technique and clinical effects of extended anterolateral approach for treatment Schatzker type II V/VI involving posterolateral column tibial plateau.From January 2015 through December 2018, 28 patients with plateau fractures were included in study. Among them, 16 treated using an lateral locking compression plate fixation. Twelve V or VI combined a medial plus All cases followed up 15 to 31 months, average follow-up 22.5 ± 3.7 months. During follow-up, angle (TPA),...
To explore the effect of shikonin on recovery nerve function after acute spinal cord injury(SCI) in rats.
Introduction: Esophageal variceal bleeding (EVB) is a potentially fatal complication of cirrhosis. The purpose the present study was to evaluate safety and efficacy novel technique balloon-occluded esophageal varices (EVs) obliteration (BEVO) for EVs classified as F2 (medium size, F2-EVs) F3 (large F3-EVs). Materials Methods: Between December 2020 2021, total 73 consecutive patients with were treated using BEVO. An injection sclerosant administered via direct puncture during balloon...