A5100391909- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Vestibular and auditory disorders
- Cleft Lip and Palate Research
- Dental Anxiety and Anesthesia Techniques
- Mental Health and Psychiatry
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Craniofacial Disorders and Treatments
- Anesthesia and Neurotoxicity Research
- Diet and metabolism studies
- Preterm Birth and Chorioamnionitis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Schizophrenia research and treatment
- Family Caregiving in Mental Illness
- Pregnancy-related medical research
- Dental Radiography and Imaging
- Gastroesophageal reflux and treatments
- Maternal and Perinatal Health Interventions
- Intensive Care Unit Cognitive Disorders
Massachusetts General Hospital
2025
Harvard University
2017-2025
Nanjing Medical University
2015-2024
China Medical University
2006-2022
Nanjing Maternity and Child Health Care Hospital
2022
First Hospital of China Medical University
2021
Brigham and Women's Hospital
2015-2017
Tongren Hospital
2015
Université Laval
2006-2009
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2006
Despite evidence of a relationship among obstructive sleep apnea (OSA), metabolic dysregulation, and diabetes, it is uncertain whether OSA treatment can improve parameters. We sought to determine effects long-term continuous positive airway pressure (CPAP) on glycemic control diabetes risk in patients with cardiovascular disease (CVD) OSA.Blood, medical history, personal data were collected substudy 888 participants the Sleep Apnea cardioVascular Endpoints (SAVE) trial which stable CVD...
Background: Post-operative delirium (POD) is a common and serious clinical condition that occurs following anesthesia/surgery. While its impact well recognized, the underlying electrophysiological mechanisms remain largely unknown, posing challenges for effective treatment. This study aims to investigate hippocampal neural dynamics before after anesthesia/surgery in aged mice, which have tendency of developing POD. Methods: included adult mice with POD model. POD-like behavior was assessed N...
Upper airway collapse does not occur during wake in obstructive sleep apnea patients. This points to wake-related compensatory mechanisms, and possibly a modified corticomotor control of upper dilator muscles. The objectives the study were characterize responsiveness genioglossus transcranial magnetic stimulation respiratory non-respiratory facilitatory maneuvers patients, compare it diaphragm, with reference normal controls.Motor evoked potentials corresponding motor thresholds, recorded...
During wakefulness, the electromyography (EMG) activities of upper airway dilator muscles are higher in OSA syndrome (OSAS) patients than those normal subjects. This is believed to be related central compensatory mechanisms. study aimed assess motor conductivity genioglossus (GG) during wakefulness and evaluate site OSAS patients.Twelve 12 subjects were recruited record evoked potential (MEP) GG transcranial magnetic stimulation applied at dominant-sided anterolateral area response third...
The coronavirus disease 2019 (COVID-19) pandemic has markedly impacted the distribution of medical resources and healthcare delivery systems. objective this study was to investigate influence on diagnosis treatment sleep-disordered breathing (SDB) in China.A retrospective online survey sleep centers from assembly SDB Chinese Thoracic Society conducted July 1 20, 2020. questionnaire focused four main aspects: 1) general information about centers; 2) changes management activities, including...
BACKGROUND:Little information exists regarding the best anesthesia method for emergency cerclage.This single-center study aimed to compare outcomes following general and spinal during cervical cerclage in women second trimester of a singleton pregnancy. MATERIAL AND METHODS:A total 297 pregnant patients were recruited: 141 assigned group 156 group. Periprocedural data obstetric recorded statistically analyzed. RESULTS:Average duration procedure was shorter than (25.78±9.4 min versus...
MB (mouth breathing) promotes the occurrence of sleep-disordered breathing even in non-apnoeic subjects. Considering that MO opening) contributes to an increase UA (upper airway) collapsibility independently MB, aim present study was assess influence route on dynamics presence MO. Bilateral anterior magnetic phrenic nerve stimulation performed 2 s after expiratory onset 12 healthy male subjects during wakefulness (age, 50+/-5 years; body mass index, 27.8+/-2.4 kg/m(2)) through a mouthpiece...
Obstructive sleep apnea (OSA) is a common clinical condition with far-reaching health implications. We aimed to analyze the published articles of OSA and compare differences in aspects years, countries, institutions, journals, authors keywords evaluate hotspots development trends research.We screened all associated literature on from Web Science (WoS) during 2011-2020 analyzed research this field using VOS viewer online bibliometric analysis platform. The BICOMB gCLUTO softwares were used...
Purpose: Tongue strength training (TST) has been shown to decrease the apnea-hypopnea index in some patients with obstructive sleep apnea (OSA). However, whether TST modulates central regulation of genioglossus and influences stability upper airway remains unknown. The purpose this study was dynamically assess effect on airway. Methods: Sixteen adult male Sprague–Dawley rats were studied explore mechanism improving function. randomly assigned normal control (NC) groups. group underwent...
ABSTRACT Objectives To evaluate changes of the upper airway and oral cavity volumes in patients with skeletal Class III malocclusion undergoing bimaxillary orthognathic surgery, to analyze correlation between postoperative decrease amount jaw movement volume reduction. Materials Methods Thirty (16 males 14 females) surgery were included. Three-dimensional reconstruction performed using preoperative (T0) (T1) (6 months) cone-beam computed tomography scans. Results The volume, sagittal area...