Bo Wei

ORCID: 0000-0002-2759-9901
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About
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Research Areas
  • Stroke Rehabilitation and Recovery
  • Helicobacter pylori-related gastroenterology studies
  • Spinal Cord Injury Research
  • SARS-CoV-2 and COVID-19 Research
  • Cerebral Palsy and Movement Disorders
  • Gastric Cancer Management and Outcomes
  • SARS-CoV-2 detection and testing
  • Immune Cell Function and Interaction
  • Esophageal and GI Pathology
  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Bone and Joint Diseases
  • Veterinary medicine and infectious diseases
  • T-cell and B-cell Immunology
  • Galectins and Cancer Biology
  • Gastrointestinal Tumor Research and Treatment
  • Infant Development and Preterm Care
  • Injury Epidemiology and Prevention
  • Eosinophilic Esophagitis
  • Cardiac and Coronary Surgery Techniques
  • Vestibular and auditory disorders
  • Esophageal Cancer Research and Treatment
  • Respiratory viral infections research

Botswana Geoscience Institute
2024

BGI Research
2024

Chinese PLA General Hospital
2024

Shenyang Medical College
2024

Liaoning University of Traditional Chinese Medicine
2024

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2024

Capital Medical University
2011-2023

Beijing Tian Tan Hospital
2021-2023

Capital University
2022

China Rehabilitation Research Center
2011-2021

COVID-19 is caused by SARS-CoV-2 infection and was initially discovered in Wuhan. This outbreak quickly spread all over China then to more than 20 other countries. fluorescent microsphere immunochromatographic test strips were prepared the combination of time-resolved fluorescence immunoassay with a lateral flow assay. The analytical performance clinical evaluation this testing method done significance verified. LLOD antibody IgG IgM 0.121U/L 0.366U/L. specificity healthy people patients...

10.1080/22221751.2020.1811161 article EN cc-by Emerging Microbes & Infections 2020-01-01

Under the trend of antibiotic resistance H. pylori leading to decrease eradication rate, development a vaccine is best choice fight against pylori. In this study, we attempted reduce amounts required antigens by using three different parenteral routes immunization and an adjuvant cGAMP (cyclic guanosine monophosphate-adenosine monophosphate) enhance immunogenicity candidate. The immune protection post-challenge responses were assessed compared in mice immunized with recombinant Helicobacter...

10.1080/21645515.2020.1744364 article EN Human Vaccines & Immunotherapeutics 2020-04-16

In recent years, the global prevalence of gastric cancer (GC) has witnessed a progressive decrease, accompanied by step-growth in incidence signet ring cell carcinoma (GSRCC). As precision medicine concepts progress, GSRCC, distinct sub-type GC, drawn considerable attention from researchers. However, there still persist some controversies regarding associated research findings. To summarize current obstacles and potential future directions for on GSRCC. begin with, all literature related to...

10.5306/wjco.v16.i2.98983 article EN World Journal of Clinical Oncology 2024-12-11

Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a pandemic. We herein report four COVID-19 cases with long-term positive viral ribonucleic acid (RNA) for about 61 days. Despite treatment recombinant human interferon, convalescent plasma from patients, arbidol, etc., nucleic results were still SARS-CoV-2. After ritonavir-boosted danoprevir (DNVr, 100/100 mg, once daily), all patients showed two to three consecutive...

10.1590/0037-8682-0372-2020 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2020-01-01

Background: Cytological detection of early esophageal squamous cell carcinoma (ESCC) remains challenging. Therefore, we introduced a rapid cytological screening method and evaluated its efficacy as pre-endoscopy for ESCC precursor lesions. Methods: This consisted sponge sample retrieval, automatic liquid-based treatment slides preparation, computer-assisted manual diagnosis. Efficacy lesions was evaluated. Also, diagnostic efficiency compared with Results: Eighty-three patients 2,090...

10.1177/15330338211066200 article EN cc-by-nc Technology in Cancer Research & Treatment 2022-01-01

<title>Abstract</title> Background Germ-free mice feature a profoundly underdeveloped immune system. Despite recent studies that emphasize the role of specific bacteria-derived metabolites in cell development and differentiation, it remains unclear how lack microbiota leads to deficiencies. Results Here we performed droplet-based single-cell RNA sequencing analyze bone marrow peripheral blood both germ-free specific-pathogen-free mice, identifying 25 distinct types. Our findings indicate...

10.21203/rs.3.rs-5288875/v1 preprint EN cc-by Research Square (Research Square) 2024-10-31

To assess the safety and efficacy of off-pump technique with normothemia to extend thoracoabdominal aortic aneurysm replacement compared traditional hypothermic circulatory arrest.From January 2004 December 2013, 128 consecutive patients underwent surgical repair (type Crawford Ⅱ) in Fuwai Hospital. The mean age was (37±11) years. included 74 cases (57.8%) chronic Stanford A dissection, 34 (26.6%) B 20 (15.6%) true aneurysm. There were 71 who arrest surgery (cardiopulmonary bypass (CPB)...

10.3760/cma.j.issn.0529-5815.2016.02.009 article EN PubMed 2016-02-01

Objective To evaluate the immunopotentiating effect of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) as an adjuvant on norovirus (GⅡ.4) virus like particles (VLPs) in development vaccine. Methods BALB/c mice were intramuscularly immunized with VLPs composed capsid protein VP1 combination cGAMP or Al(OH)3. Norovirus VLPs-specific antibodies serum detected by ELISA. A synthetic histo-blood group antigen (HBGA)-VLPs blocking assay was used to analyze neutralizing against...

10.3760/cma.j.issn.0254-5101.2017.10.007 article EN Zhonghua weishengwuxue he mianyixue zazhi 2017-10-31

Malaria is listed as one of the three most hazardous infectious diseases worldwide. Travelers and migrants passing through exit entry ports are important sources malaria pandemics globally. Developing accurate rapid detection technology for important. Here, a novel hairpin-mediated amplification (HMA) technique was proposed four Plasmodium species, including P. falciparum, vivax, malariae, ovale. Based on conserved nucleotide sequence Plasmodium, specific primers probes were designed HMA...

10.3390/mi14101917 article EN cc-by Micromachines 2023-10-09
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