Mingyu Li

ORCID: 0000-0002-3019-9212
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About
Contact & Profiles
Research Areas
  • Electronic Packaging and Soldering Technologies
  • Extraction and Separation Processes
  • 3D IC and TSV technologies
  • Horticultural and Viticultural Research
  • Fermentation and Sensory Analysis
  • RNA modifications and cancer
  • Dental Erosion and Treatment
  • Dental materials and restorations
  • Plant biochemistry and biosynthesis
  • Advanced Welding Techniques Analysis
  • Aluminum Alloys Composites Properties
  • Nanomaterials and Printing Technologies
  • Cancer-related molecular mechanisms research
  • Oral microbiology and periodontitis research
  • Cloud Computing and Resource Management
  • Peptidase Inhibition and Analysis
  • Injection Molding Process and Properties
  • Advanced biosensing and bioanalysis techniques
  • Intermetallics and Advanced Alloy Properties
  • Membrane Separation and Gas Transport
  • Fungal and yeast genetics research
  • TiO2 Photocatalysis and Solar Cells
  • Plant and animal studies
  • Carbon Nanotubes in Composites
  • Nanotechnology research and applications

Ministry of Agriculture and Rural Affairs
2024-2025

China Agricultural University
2024-2025

Shenzhen University
2008-2025

Zhengzhou University
2025

Shanghai Jiao Tong University
2010-2024

Harbin Institute of Technology
2005-2024

State Key Laboratory of Advanced Welding and Joining
2024

Ningxia Medical University
2024

PLA Army Engineering University
2024

Shijiazhuang University
2024

Dental caries and periodontal diseases have a close relationship with microbes such as Streptococcus mutans, Porphyromonas gingivalis Fusobacterium nucleatum. Graphene oxide (GO), the derivative of graphene, plays an important role in many areas including biology medicine. In particular, it has been known promising antimicrobial nanomaterial. this study, we focused on property GO against dental pathogens. With utilization 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT)...

10.1021/acsami.5b01069 article EN ACS Applied Materials & Interfaces 2015-02-23

N6-methyladenosine (m6A) RNA modification plays a critical role in various physiological and pathological conditions. However, the of m6A head neck squamous cell carcinoma (HNSCC) remains elusive.In this study, expression demethylases was detected by HNSCC tissue microarray. m6A-RNA immunoprecipitation (MeRIP) sequencing were used to identify downstream targets ALKBH5. Comprehensive identification RNA-binding proteins mass spectrometry (ChIRP-MS) explore "readers". Tumor-infiltrating...

10.1186/s12943-022-01572-2 article EN cc-by Molecular Cancer 2022-04-09

Aggregation-induced emission (AIE) or aggregation-induced enhancement (AIEE) has endowed gold species with responsive fluorescent properties, favoring their potential applications in sensing, imaging, and therapy. However, it remains an interesting challenge to fabricate fluorophores both AIE AIEE effects. Herein, we presented highly luminescent Au(I) thiolate nanocomplex-based biosensors Zn2+ induced-AIE zeolite imidazolate framework (ZIF-8) induced-AIEE The nonemissive monovalent...

10.1021/acs.analchem.4c05119 article EN Analytical Chemistry 2025-01-22

Oral squamous cell carcinoma (OSCC) is affected by the interaction between oral pathogen and holobionts, or combination of host its microbial communities. Studies have indicated structure feature microbiome in OSCC tissue saliva, relationships microbiota sites, stages remain unclear. In present study, (T), saliva (S) mouthwash (W) samples were collected from same subjects carried out study 16S sequencing. The results showed T group was significantly different S W groups with character lower...

10.3389/fmicb.2019.01439 article EN cc-by Frontiers in Microbiology 2019-06-26

We designed and synthesized synI, which is ∼21.6% shorter than native chrI, the smallest chromosome in Saccharomyces cerevisiae. SynI was for attachment to another synthetic due concerns surrounding potential instability karyotype imbalance now attached synIII, yielding first yeast fusion chromosome. Additional chromosomes were constructed study nuclear function. ChrIII-I chrIX-III-I have twisted structures, depend on silencing protein Sir3. As a smaller chromosome, chrI also faces special...

10.1016/j.xgen.2023.100439 article EN cc-by-nc-nd Cell Genomics 2023-11-01

Genetic variants among individuals have been associated with ineffective control of hypertension. Previous work has shown that hypertension a polygenic nature, and interactions between these loci variations in drug response. Rapid detection multiple genetic high sensitivity specificity is needed for the effective implementation personalized medicine treatment Here, we used cationic conjugated polymer (CCP)-based multistep fluorescence resonance energy transfer (MS-FRET) technique to...

10.1126/scitranslmed.abq5753 article EN Science Translational Medicine 2023-03-08

Abstract Background Secondary caries is responsible for 60 percent of all replacement restorations in the typical dental practice. The diversity bacterial sources and different types filling materials could play a role secondary caries. aim this study was to determine compare microbial spectrum biofilms around amalgam composite resin restorations. Methods Clinical samples were collected from freshly extracted teeth diagnosed with clinical Samples categorized into four groups according...

10.1186/1471-2334-10-241 article EN cc-by BMC Infectious Diseases 2010-08-17

Pyruvate kinase M2 as a key rate-limiting enzyme in glycolysis, it plays critical role metabolic reprogramming and carcinogenesis. However, whether PKM2 can promote immunosuppressive microenvironment formation remains unknown head neck squamous cell carcinoma (HNSCC). expression was detected using immunohistochemical staining. The biological functions of were investigated vitro vivo. Lactate production the Galectin-9, immunosuppression molecule, after knockdown overexpression HNSCC cells....

10.1038/s41419-021-03990-4 article EN cc-by Cell Death and Disease 2021-07-21

Runt-related transcription factor 2 (Runx2) is involved in the early stage of tooth development. However, only few studies have reported role Runx2 enamel development, which may be attributed to that full knockout mice cannot survive after birth. In present study, we successfully established a Runx2-deficient mouse model using conditional (cKO) method. We observed significant reduction degree mineralization and decreased size rods cKO mice. Histological analysis showed retained proteins...

10.1038/s41598-018-27873-5 article EN cc-by Scientific Reports 2018-06-19

AA 1060 aluminum alloy underwent roll bonding with reductions of 25% and 35%, followed by accumulative (ARB) for up to seven cycles at ambient temperature. The evolution surface layer texture throughout the ARB process was analyzed using X-ray diffraction. Initially, cube progressively transitioned r-cube ARB, orientation intensity increases from 0 9.2 as true strain accumulates. shear quantified through mathematical formulations volume fractions accumulated strain. rate (dMi/dε) reduction...

10.3390/cryst15040369 article EN cc-by Crystals 2025-04-17
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