Xu Shuai

ORCID: 0000-0002-3702-4714
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Anesthesia and Pain Management
  • Scoliosis diagnosis and treatment
  • Animal Virus Infections Studies
  • Aquaculture disease management and microbiota
  • Radio, Podcasts, and Digital Media
  • Advanced Mathematical Theories and Applications
  • IL-33, ST2, and ILC Pathways
  • Engineering and Information Technology
  • Cancer-related molecular mechanisms research
  • Atmospheric chemistry and aerosols
  • Psoriasis: Treatment and Pathogenesis
  • Diverse Applied Research Studies
  • Endometriosis Research and Treatment
  • Iterative Methods for Nonlinear Equations
  • RNA regulation and disease
  • Business, Innovation, and Economy
  • Chemical and Physical Properties in Aqueous Solutions
  • Multimedia Communication and Technology
  • Public Procurement and Policy
  • Advancements in Transdermal Drug Delivery
  • Air Quality and Health Impacts
  • Student Stress and Coping
  • Effects of Vibration on Health
  • Influenza Virus Research Studies

Peking University
2022-2025

Vanderbilt University
2023-2025

Lanzhou Veterinary Research Institute
2025

Chinese Academy of Agricultural Sciences
2025

Lanzhou University
2025

Peking University People's Hospital
2022-2025

Hubei University
2023-2024

Renmin University of China
2024

Jining First People's Hospital
2022

Weatherford College
2022

Abstract Interleukin-37 (IL-37) possesses the function of down-regulate systemic and local inflammation. It is unknown whether IL-37 expressed in human regulatory T cells (Tregs) its role modulating immune response Tregs. In present study, cell surface molecules secretory cytokines were analyzed order to determine regulating inhibitory effect CD4 + CD25 Meanwhile, effects on differentiation proliferation as co-culture Treg/CD4 − also investigated. was showed that cytoplasm Tregs levels...

10.1038/srep14478 article EN cc-by Scientific Reports 2015-09-28

N 6-methyladnosine (m 6 A) modification is present in both positive- and negative-strand RNA of influenza A virus (IAV) affects the replication pathogenicity IAV. However, little known about regulatory mechanism m IAV RNA. In study, we identified methylation viral different subtypes confirmed that promotes polymerase activity By mutating motifs on multiple RNAs (vRNAs) IAV, revealed deficiency vRNA suppresses expression genes vitro. addition, reduced a mouse model. Mechanistically, assembly...

10.1073/pnas.2411554122 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2025-03-12

Abstract Introduction: Inflammation is a hallmark of cancer. DNA methylation (DNAm) derived immune cell type proportions and circulating inflammation-related protein markers are precise measures inflammatory phenotypes. We investigated the associations DNAm-derived phenotypes with risks anal cancer precancer (high-grade squamous intraepithelial lesions, HSIL) among men HIV. Method: matched 22 cases to 37 controls normal epithelium 54 HSIL 90 using propensity score methods. DNAm data were...

10.1158/1538-7445.am2025-6217 article EN Cancer Research 2025-04-21

Study Design. An exploratory study Objective. The purpose of this is to investigate the prevalence scoliosis in Linxia Prefecture, Gansu Province, China, and explore characteristics electronic devices school screening (SSS). Summary Background Data. Forward bend test Scoliometer are common methods for SSS. advantages 3-Dimensional (3D) ultrasound system SSS have been reported before. While there a paucity evidence compare manual (M-Scoliometer) with (E-Scoliometer) correlation between angle...

10.1097/brs.0000000000005377 article EN Spine 2025-04-29

In numerous developing nations, the pervasive practice of crop residue incineration is a principal contributor to atmospheric contamination in agricultural operations. This study examines repercussions such biomass combustion on air quality during autumnal harvest season, utilizing data acquired from satellite-based remote sensing fire events and pollution measurements. Employing wind direction information alongside difference-in-difference fixed-effects methodologies, this investigation...

10.1371/journal.pone.0303830 article EN cc-by PLoS ONE 2024-05-17

The Methodist DeBakey Cardiovascular Journal provides timely updates on important topics in cardiovascular medicine with quarterly, thematic review-article issues. Each issue is curated by subject-matter-expert guest editors and includes invited reviews along case reports, interesting multimodality images, humanities submissions. Additional CME quizzes, editorials are published a continuous basis online. MDCVJ geared towards cardiologists, surgeons, general practitioners, CV residents...

10.14797/mdcvj.186 article EN cc-by-nc Methodist DeBakey Cardiovascular Journal 2010-01-01

Abstract Introduction Genome-wide association studies (GWAS) have identified >60 genomic loci for lung cancer risk. However, causal genes and the underlying biological mechanisms most of these remain unknown. Therefore, we conducted a multi-omics study to identify susceptibility genes. Method We first transcriptome-wide (TWAS) using S-PrediXcan framework. Whole transcriptome data from adjacent-normal tissue samples 304 European-ancestry patients were used build genetic prediction...

10.1158/1538-7445.am2024-lb146 article EN Cancer Research 2024-04-05

Understanding the spatiotemporal evolution trends and impact factors of landscape ecological risks is crucial for maintaining regional ecosystem security. However, research has predominantly focused on past analytical paradigm, which often lacked strategic predictions future scenarios tailored to diverse developmental requirements. This study land use changes in Huai River Basin during 2000, 2010, 2020 used Future Land Use Simulation (FLUS) model conduct multi-scenario simulation spatial...

10.2139/ssrn.4805178 preprint EN 2024-01-01

Yellow catfish is one of the most important aquaculture species in China, with an annual output 565,000 tons. Between May and July 2022, farmed yellow experienced unusually high mortality rate farm next to Futou Lake Hubei, China. Diseased fish exhibited symptoms including ascites, skin ulcers, bleeding head, oral cavity, lower jaw base. Polymerase chain reaction (PCR) sequence analyses confirmed co-infection Catfish Calicivirus (YcCV) Aeromonas veronii diseased fish. Transmission electron...

10.3390/ani14223289 article EN cc-by Animals 2024-11-15

Acute graft-versus-host disease (GvHD) is a process that classically has been defined as occurring less than 100 days after stem cell transplant. When Stage IV cutaneous acute GvHD occurs outside this window, it can be difficult to distinguish clinically from toxic epidermal necrolysis (TEN). A 50-year-old man with diffuse large B-cell lymphoma who had undergone an allogeneic transplant 20 months previously was admitted for neutropenic septic shock. He developed slowly progressing...

10.5070/d32310036996 article EN cc-by-nc-nd Dermatology Online Journal 2017-01-01

近些年来随着生境的破坏其分布面积急遽下降,较大面积连续分布的海草床已经非常少见。本研究首次将声呐探测技术应用到海草床时空分布特征的相关研究中,在河北唐山乐亭-曹妃甸沿海发现目前中国面积最大的鳗草(Zostera marina)海草床,海草床面积高达29.17km2,绘制了鳗草分布图和水深分布图,并对鳗草生物量和茎枝高度等基本生物学指标进行了调查。该发现极大丰富了中国海草数据库,并为鳗草的深入研究及保护提供了得天独厚的实验基地,也为周边海洋牧场的构建打下良好的基础。

10.11759/hykx20190318003 article ZH-CN 2019-08-15

Abstract Background Limited and inconsistent epidemiological evidence for the relationship between vitamin D level risk of osteosarcopenic obesity. We aimed to find out serum 25-(OH)-D 3 Methods This study was a cross-sectional study. Residents from nine communities Tiexi District Shenyang City were enrolled May October 2017. included 4,506 eligible participants (1,601 men) analyses. Participants asked an overnight fast. Thereafter, Blood samples collected, estimated using liquid...

10.21203/rs.3.rs-84790/v1 preprint EN cc-by Research Square (Research Square) 2020-10-07

H5N6 influenza A virus (IAV) is a newly emerged zoonotic pathogen which seriously poses threat to public health, and the scientific questions on its replication pathogenesis need further investigation. Filamin (filamin A, FLNA) multifunctional actin binding protein, serves as scaffold in signaling transduction participate many cellular processes. However, little known about role interactions between host immune response. In this study, based analysis of deep-sequencing previously, it was...

10.1360/n052018-00200 article EN Scientia Sinica Vitae 2018-11-19

Spinal abnormality surgery, including surgery for ankylosing spondylitis and idiopathic scoliosis, can present significant challenges to anesthesiologists because of the potential difficult airway. The bedside screening tests routinely used detect airways are highly variable. Pharynx volume calculated using three-dimensional (3D) computed tomography (CT) may play a role in predicting airways. We conducted retrospective cohort study on patients (aged ≥14 years) who received orthopedic...

10.1097/md.0000000000031139 article EN cc-by-nc Medicine 2022-10-14
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