- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- Renal cell carcinoma treatment
- Gout, Hyperuricemia, Uric Acid
- Global Health Care Issues
- Cancer Genomics and Diagnostics
- Thermoregulation and physiological responses
- Renal and related cancers
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Air Quality Monitoring and Forecasting
- Cardiovascular Health and Risk Factors
- Lung Cancer Treatments and Mutations
- Cardiovascular Disease and Adiposity
- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Alcohol Consumption and Health Effects
- Immune cells in cancer
- Heavy Metal Exposure and Toxicity
- Health, Environment, Cognitive Aging
- Lipid metabolism and disorders
- Metabolism, Diabetes, and Cancer
- Dialysis and Renal Disease Management
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
Beijing Hospital of Traditional Chinese Medicine
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2025
Lanzhou University
2015-2025
National Center for AIDS/STD Control and Prevention,China CDC
2022
Chinese Center For Disease Control and Prevention
2022
State Key Laboratory of Infectious Disease Prevention and Control
2022
GlaxoSmithKline (United States)
2019-2021
Tianjin Medical University
2015
Huazhong University of Science and Technology
2015
University of Cincinnati
2001
Abstract Multiple synchronous lung cancers (MSLCs) present a clinical dilemma as to whether individual tumours represent intrapulmonary metastases or independent tumours. In this study we analyse genomic profiles of 15 adenocarcinomas and one regional lymph node metastasis from 6 patients with MSLC. All demonstrate distinct profiles, suggesting all are primary tumours, which consistent comprehensive histopathological assessment in 5 the patients. Lung same individuals no more similar each...
Air pollution exposure may play an adverse role in diabetes. However, little data are available directly evaluating the effects of air blood lipids which dysfunction has been linked to diabetes or its complications. We aimed evaluate association between and level among type 2 diabetic patients Northwest China. performed a population-based study 3912 ongoing cohort Both spline multiple linear regressions analysis were used examine short-term PM10, SO2, NO2 total cholesterol (TC),...
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new concept, proposed in 2020; however, its applicability Asia populations has yet to be evaluated. Therefore, we aimed compare the difference epidemiological and clinical characteristics between MAFLD non-alcoholic (NAFLD) among Asian populations.
Diurnal temperature range (DTR) is an important index of climate change and variability. It also a risk factor affecting human health. However, limited evidence available to illustrate the effect DTR modification on cause-specific cardiovascular disease among elderly. A semi-parametric generalized additive model (GAM) was used analyze exposure-effect relationship between daily emergency room (ER) admissions for diseases elderly from 2009 2011 in Beijing. We examined effects stratified groups...
A 35-year-old man with painful and difficult urination underwent 18 F-FDG Al F-Thretide PET/CT scans after a pelvic MRI suggested prostate mass. The revealed mass accompanied by an intravenous tumor thrombus. Both the thrombus demonstrated increased FDG uptake. Intense PSMA activity was observed in both lesions, showing considerably higher compared its Histologic analysis of biopsy confirmed diagnosis prostatic synovial sarcoma. immunohistochemistry showed high expression vascular...
The prevalence of CRF07_BC is 39.7% and has become the most infectious HIV strain in China. To study transmission diffusion trajectory China to prevent further expansion its transmission. A total 16,635 sequences pol gene were collected from 1997-2020. We characterized subtypes according a phylogenetic tree analysis. 0.50% molecular network was constructed analyze relationship among different provinces for two epidemic clusters. Spatial temporal propagation characteristics analyzed...
Smoking is a recognized risk factor for chronic kidney disease (CKD), and cotinine hydroxycotinine are tobacco metabolites that can be used to quantify smoking. This study evaluated their relationship with CKD in smokers. secondary dataset analysis based on National Health Nutrition Examination Survey (NHANES) data from 2013 2018. A cross-sectional examination of subsample 2930 adult smokers aged ≥20 years was conducted investigate the between serum its metabolite, hydroxycotinine, CKD....
While the relationship between albumin corrected calcium (ACC) levels and unfavourable outcomes has been previously investigated, existing studies have limited in their specific application to patients undergoing maintenance hemodialysis (MHD) intensive care unit (ICU). This retrospective cohort study aimed explore association baseline ACC 28-day in-hospital mortality ICU MHD. Logistic regression model, smooth curve fitting, piecewise linear regression, subgroup analyses, a series of...
Objective To determine whether metabolic syndrome (MetS) and its components are risk factors for breast cancer among postmenopausal women in China.Methods Based on the baseline data of Jinchang Cohort, a case–control study was carried out women, including 43 cases 86 controls. Both MetS were evaluated. Odds ratios 95% confidence intervals (CI) association estimated by conditional logistic regression analysis.Results The odds ratio 3.505 (95% CI 1.282–9.583) MetS, 3.016 1.044–8.715) body mass...
Abstract Objective Both exposure to heavy metals and alcohol intake have been related the risk of type 2 diabetes (T2D). In this study, we aimed assess potential interactions between metal on T2D prediabetes in a cohort Chinese male workers. Methods We conducted cross‐sectional analysis 26,008 workers an occupational study from 2011 2013. assessed consumption at baseline these who were aged ≥20 years. Based occupations which categorized according measured urine levels, multiple logistic...
Non-metastatic renal cell carcinoma (RCC) with tumor thrombus showed a greater tendency for developing metastases after surgery. Early identification of patients high risk poor prognosis is especially important to explore adjuvant treatment improving outcomes. Neutrophil-to-lymphocyte ratio (NLR) was systemic inflammation marker and outcome predictor in RCC, reflecting the chaos immune status cancer as myeloid expansion lymphatic suppression. Neutrophil extracellular traps (NET) formation...
Abstract Background To study the association between anthropometric measurements and risk of diabetes impaired fasting glucose (IFG) compare body mass index (BMI), waist circumference (WC), waist‐to‐height ratio (WHtR) to determine best indicator its optimal cutoffs for predicting type 2 IFG. Methods A Chinese prospective (2011‐2019) cohort named Jingchang that included 48 001 participants was studied. Using Cox proportional hazard models, ratios (HRs) incident or IFG per 1 SD change in BMI,...
This retrospective cohort study assessed short- and long-term economic, clinical burden, productivity impacts of acute pancreatitis (AP) in the United States.United States claims data from patients hospitalized for AP (January 1, 2011-September-30, 2016) were sourced MarketScan databases. Patients categorized by index severity: severe intensive care unit (ICU), non-ICU, other patients.During index, 41,946 or visited an emergency department AP. For inpatients, median (interquartile range)...