A5102985271- Hepatitis B Virus Studies
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Circadian rhythm and melatonin
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Neuroinflammation and Neurodegeneration Mechanisms
- Acupuncture Treatment Research Studies
- Sleep and Wakefulness Research
- Biofield Effects and Biophysics
- Diet, Metabolism, and Disease
- Traditional Chinese Medicine Studies
- Nutrition, Genetics, and Disease
- Educational Environments and Student Outcomes
- Gout, Hyperuricemia, Uric Acid
- Dietary Effects on Health
- Cardiovascular Health and Risk Factors
- Psychological and Temporal Perspectives Research
- Spondyloarthritis Studies and Treatments
- Ginseng Biological Effects and Applications
- Viral-associated cancers and disorders
- Advances in Cucurbitaceae Research
- Retirement, Disability, and Employment
- Sleep and related disorders
- Bioinformatics and Genomic Networks
Huazhong University of Science and Technology
2017-2024
Tongji Hospital
2017-2024
Kyrgyz National University
2024
Nanjing University of Chinese Medicine
2022-2024
National Cheng Kung University Hospital
2024
University of Shanghai for Science and Technology
2024
Xiamen University
2019-2023
Lanzhou University
2019-2021
National Cheng Kung University
2008-2009
Heidelberg University
2008
Jiao-tai-wan (JTW), a classic herbal formula of traditional Chinese medicine recorded in Han Shi Yi Tong, has been used to alleviate sleep disorders since ancient times. In modern pharmacological research, JTW adopted for treating diabetes mellitus and even exerts antidepressant effects. However, the potential mechanisms deserve further elucidation. The prevalence combined with depressive disorder (DD) is continuing increase, yet it currently under-recognized its treatment remains...
Adenosine 2A receptor (A2AR) exerts protective roles in endotoxin‐ and/or ischemia‐induced tissue damage. However, the role for A2AR nonalcoholic fatty liver disease (NAFLD) remains largely unknown. We sought to examine effects of global myeloid cell‐specific disruption on aspects obesity‐associated NAFLD and elucidate underlying mechanisms. Global cell–specific A2AR‐disrupted mice control were fed a high‐fat diet (HFD) induce NAFLD. In addition, bone marrow–derived macrophages primary mouse...
BACKGROUND:Acupuncture, which has many good effects and few adverse effects, is widely recognized as an alternative therapy for depression in clinical practice. This study aimed to explore the mechanism of acupuncture antidepressant treatment. MATERIAL AND METHODS:In this experiment, Sprague-Dawley rats were randomly divided into 4 groups: control, chronic unpredictable mild stress (CUMS), acupuncture, fluoxetine groups. The CUMS, groups orphaned subjected 6 weeks, treated with their...
Oxidative stress is closely related to the occurrence of depression. Acupuncture has been proved be an effective method for treating In order explore mechanism antidepressant effect acupuncture, this study performed acupuncture prevention on chronic unpredictable mild (CUMS) depression model rats, and observed hippocampal oxidative Nrf2 signaling pathway. Male SD rats were randomly divided into control group, CUMS fluoxetine group (n = 10/group). Fluoxetine, a common antidepressant, was used...
Purpose. To explore the therapeutic efficiency of acupuncture and related molecular mechanism neural plasticity in depression. Methods. Chronic unpredictable mild stress- (CUMS-) induced rats were established for depression animal model. There a total four rat groups, including control group, CUMS CUMS+acupuncture CUMS+fluoxetine group. The group fluoxetine given 3-week treatment after modeling intervention. researcher performed open-field, elevated plus maze, sucrose preference tests to...
Abstract Over the past decade, learning engagement has received increasing attention from researchers. As a critical factor in college students’ academic achievement, is significant long-term future development and social creativity. Present studies show that overall level of low, which highly unfavourable to educational quality development. There no doubt about position university library circles. However, influence environment on not been fully explored. The data this study came survey 45...
Abstract Background The incidence of diabetes mellitus (DM) and depression is increasing year by around the world, bringing a serious burden to patients their families. Jiao-tai-wan (JTW), well-known traditional Chinese medicine (TCM), has been approved have hypoglycemic antidepressant effects, respectively, but whether JTW such dual effects its potential mechanisms still unknown. This study evaluate therapeutic on chronic restraint stress (CRS)-induced DM combined with mice, explore...
Abstract Background Chronic hepatitis B virus (HBV) infection is an important cause of hepatocellular carcinoma (HCC) worldwide. The pre-S 1 and -S 2 mutant large HBV surface antigen (LHBS), in which the regions LHBS gene are partially deleted, highly associated with HBV-related HCC. Methods region two hundred one HBV-positive serum samples was PCR-amplified sequenced. A oligonucleotide chip developed to efficiently detect deletions chronic carriers. Twenty from carriers were analyzed using...
Jiao-tai-wan (JTW) has been often used to treat insomnia and diabetes mellitus. Recent studies found its antidepressant activity, but the related mechanism is not clear. This study evaluate therapeutic effects of JTW on chronic restraint stress (CRS)-induced depression mice explore potential mechanisms.CRS was set up a model. Mice in different groups were treated with 0.9 % saline, fluoxetine. After last day CRS, behavioral tests conducted. The levels neurotransmitters, inflammatory...
ABSTRACT In the context of COVID-19 pandemic, this research aimed to explore relationship between dormitory environment, learning engagement, and mental health among college students, with a special focus on students different gender groups. We conducted cross-sectional survey from 45 universities in China. For health, we tested for depression using 5-Item WHO Well-Being Index (WHO-5). The environment is exemplified by typical four-person layout China, which assessed four main areas: site...
Jiao-Tai-Wan (JTW), composed of Rhizome Coptidis and Cortex Cinnamomi, is a classical traditional Chinese prescription for treating insomnia. Several in vivo studies have concluded that JTW could exert its therapeutical effect insomnia rats. However, the specific mechanism still unclear. The present study aimed to explore on sleep obesity-resistant (OR) rats with chronic partial deprivation (PSD) clarify possible mechanism.JTW was prepared main components contained granules were identified...
Abstract Background To study the association between anthropometric measurements and risk of diabetes impaired fasting glucose (IFG) compare body mass index (BMI), waist circumference (WC), waist‐to‐height ratio (WHtR) to determine best indicator its optimal cutoffs for predicting type 2 IFG. Methods A Chinese prospective (2011‐2019) cohort named Jingchang that included 48 001 participants was studied. Using Cox proportional hazard models, ratios (HRs) incident or IFG per 1 SD change in BMI,...
BACKGROUND:Depression is a major mood disorder. Some patients have been reported to improve following acupuncture. This study aimed investigate the effects of acupuncture on behaviors associated with depression in chronic unpredictable mild stress (CUMS) rat model. The expression signaling pathway components nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) hippocampus plasma were also measured. MATERIAL AND METHODS:Male Sprague-Dawley rats (N=40) divided into control group (N=10),...
Objective: To explore the relationship between lipid indicators and incidence of diabetes, to compare diabetes prediction identification power traditional combined indicators, in order best alternative for identifying predicting diabetes. Methods: Based on Jinchang cohort, a nested case-control study was conducted 1 025 new cases after excluding patients with malignant tumor related endocrine, circulatory system disease, then an age (±2 years), gender matched 1∶1 control group set analyze...