A5086227577- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Head and Neck Anomalies
- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Vestibular and auditory disorders
- Teratomas and Epidermoid Cysts
- Tracheal and airway disorders
- Studies on Chitinases and Chitosanases
- Congenital Ear and Nasal Anomalies
- Nasal Surgery and Airway Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Salivary Gland Tumors Diagnosis and Treatment
- Nanocomposite Films for Food Packaging
- Hearing Loss and Rehabilitation
- Reconstructive Facial Surgery Techniques
- Invertebrate Immune Response Mechanisms
- Vascular Tumors and Angiosarcomas
- Obstructive Sleep Apnea Research
- Meningioma and schwannoma management
- Cancer and Skin Lesions
- Glaucoma and retinal disorders
- Soft tissue tumors and treatment
- Facial Nerve Paralysis Treatment and Research
- NF-κB Signaling Pathways
Inje University Busan Paik Hospital
2013-2024
University of California, San Diego
2021
Inje University
2008-2020
Dong-A University
2014
Busan Medical Center
2011-2014
CHA University
1999
<b><i>Objective:</i></b> To investigate the time course of tinnitus changes in patients receiving cochlear implantation (CI) a prospective, multicenter setting and to determine related factors. <b><i>Materials Methods:</i></b> A total 79 adult who underwent CI were included this study. We used same questionnaires sequentially 5 times. The Visual Analog Scale (VAS) for severity, Tinnitus Handicap Inventory (THI), Beck's Depression Index (BDI),...
Objectives: Surgical procedures for chronic ear disease can be grossly divided into two tympanoplasty procedures: canal wall–up and wall–down (CWD) mastoidectomies. The choice depends on the surgeon’s preference. Epitympanoplasty with mastoid obliteration (EMO) has shown postoperative results similar to those of CWD mastoidectomy long-term follow-up. In this study, we compared outcomes EMO in preoperatively sclerotic cavities cholesteatoma, otitis media poor eustachian tube function, or...
Chitin is a recognition element for tissue infiltration by innate cells implicated in allergy and helminth immunity, this process can be negatively regulated vertebrate chitinases. Acidic mammalian chitinase (AMCase) chitotriosidase (ChT) have chitinolytic activity, but little known about their roles nasal polyps.A prospective controlled study.A tertiary referral center.Nineteen subjects with polyps 12 deviated septums were recruited to obtain inferior turbinate mucosa samples. The...
Background Methotrexate (MTX) is a very effective treatment for chronic inflammatory diseases that induces apoptosis in nasal polyps (NPs). However, the precise apoptotic pathway NPs remains unclear. The aim of this study was to identify signaling pathways activated by MTX NPs. Methods NP tissues were organ cultured using an air–liquid interface method. Cultures maintained presence or absence (10 100 μM) 24 hours. To investigate NPs, we performed reverse transcription–polymerase chain...
Jae Hyen Kim, M.D., Ja Young Lee, Hye Ran Kyung Wook Heo, Seong Kook Park, M.D.,Jeong Nyeo Seong-Mi Yu, Ph.D., and Jeong Hwan Shin, M.D.. Korean J Lab Med 2008;28:196-200. https://doi.org/10.3343/kjlm.2008.28.3.196
Abstract Objective: After excision of a preauricular sinus, head bandage compressive dressing is usually used to reduce dead space and decrease the risk recurrence. However, such use may cause various problems. We assessed new method dressing, using suture transfixion silicone sheets former sinus tract, following excision. Methods: This retrospective study reviewed medical records patients undergoing in tertiary referral centre over five-year period. underwent sheets. Post-operative outcomes...
Chitin is a recognition element for tissue infiltration by innate cells implicated in allergy and immunity. This process can be negatively regulated vertebrate chitinases. Both acidic mammalian chitinase (AMCase) chitotriosidase (ChT) have chitinolytic activity. study aimed to determine the activities of AMCase ChT nasal polyps (NPs), as well their situ localization NP tissue.AMCase NPs were compared with those inferior turbinate samples. Tissue samples measured at range pHs using...
Chronic rhinosinusitis (CRS), otitis media with effusion (OME), and allergic rhinitis (AR) are common conditions that have been associated hypertrophied adenoids in children, adenoidectomy is clinically recommended. The investigators assayed the expression level site of acidic mammalian chitinase (AMCase) chitotriosidase (ChT) children to determine levels 2 chitinases relation CRS, OME, AR.A prospective cohort study.A tertiary care facility.Hypertrophied from 41 were harvested during...
이비인후과학교실, 10
Background The transsphenoidal approach (TSA) is the procedure of choice for vast majority pituitary neoplasms. Sinusitis considered a contraindication to TSA because possible transcranial spread infection. This study was performed determine if tumors could be extended patients with adenoma and chronic rhinosinusitis (CRS). Methods Medical records, including rhinologic outcomes, were retrospectively assessed in 11 consecutive who underwent concurrent endoscopic sinus surgery (ESS) CRS...
Purpose: Epidermal growth factor (EGF) has been found to be associated with the development and repair mechanisms of several renal diseases. In this study, we hypothesized that single nucleotide polymorphisms (SNPs) in EGF or its receptor genes might have an association end-stage disease (ESRD) acute allograft rejection (AR) a Korean population.Methods: Three-hundred forty seven recipients first transplants for ESRD, including 63 AR patients along 289 healthy adults were included study. Five...
Objectives: We evaluated the relationship between pathological nasal conditions and middle ear on a large-scale epidemiological basis, conducted as cross-sectional study at population level using Korean National Health Nutrition Examination Survey (KNHANES) data.Study design: A study.Methods: In retrospective cohort study, we analyzed data from KNHANES (2008–2012), which used stratified, multi-stage, probability-cluster sampling method in rolling survey of South citizens.Results: The...
The purpose of this study was to determine the prognostic potential admission a patient for idiopathic sudden sensorineural hearing loss (ISSNHL).Retrospective clinical study.We conducted retrospective 301 patients with ISSNHL. were divided into (57 at out-patients department (OPD) based treatment, using systemic steroids and intra-tympanic (IT) steroid injection) control groups (301 admission, IT injection). We compared success rate (15 dB cut off), Siegel's criteria gain decibels between...
Otitis media (OM) is one of the largest public health problems children and has devastating impacts in developing countries. The substantial medical human costs involved have led to research understand disease improve treatment. Animal models OM yielded critical information about immune, inflammatory genetic mechanisms OM. However, it important link animal studies immune responses. In recent years, “humanized” mice become a valuable tool study system an model. Here we describe first use...
Methotrexate (MTX) is very effective when used to treat chronic inflammatory diseases, and also induces apoptosis in nasal polyps (NPs). Increasing evidence suggests that Fas-Fas ligand (FasL) interactions activate multiple pathways involved the regulation of immune cell functions. The aim present study was identify activated by Fas signaling NPs were treated with MTX.Nasal tissues cultured using an air-liquid interface organ culture method. Cultures maintained absence or presence MTX (10...
Background Cells of the innate immune system that are implicated in allergy and immunity bind to chitin during tissue infiltration a process negatively regulated by vertebrate chitinases. Both acidic mammalian chitinase (AMCase) chitotriosidase (ChT) exert chitinolytic activity. The levels activities these enzymes nasal polyps (NPs) subjects who smoke or suffer from allergies unknown. In present work, we measured AMCase ChT NPs smokers allergic subjects. Methods We report prospective cohort...
서 론 ㅤ 새성기관에 발생하는 선천성 이상은 하악각이나 이주에서 경부의 하부까지 어느 부위에서든지 발생할 수 있으며, 종류 로는 기원에 따라 제1, 제2, 제3 그리고 제4 새열 이상으로 분류된다.새성 기형의 가장 흔한 형태는 제2새성 형 태이며, 치료는 수술적으로 완전히
Background: The aim of our study is to evaluate the auditory nerve and brainstem function normal hearing individuals with tinnitus without using response (ABR). Methods: Twenty three (study group) 23 (control were participated in study. ABR parameters [latency waves l, lll, V; interpeak intervals l-lll, lll-V, l-V; amplitude wave ratio between V I (V/I), III (III/I)] compared two groups. Results: results from normal-hearing within limits. However, group showed tendency prolongation latencies...
Chronic otitis media with or without cholesteatoma progresses various degrees of bone resorption and remodeling. Estrogen mediates osteoprotective effects through the receptor activator NF-κB ligand (RANKL) pathway, which is mainly mediated by estrogen receptor-alpha (ER-α).The present study investigated expression patterns (RANK), osteoprotegerin (OPG), RANKL, ER-α in pathological tissue from patients chronic to determine roles those factors osteolytic mechanisms underlying pathogenesis...
Osteopathia striata with cranial sclerosis (OSCS) is a rare genetic disorder characterized by skeletal abnormalities, sclerosis, and various associated features. In this case report, we present the of patient OSCS who complained unilateral facial palsy. We discuss clinical presentation, radiological findings, analysis, highlighting importance early diagnosis multidisciplinary management in these cases.