A5074890160- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Birth, Development, and Health
- Epigenetics and DNA Methylation
- Genetic Associations and Epidemiology
- Health disparities and outcomes
- Air Quality and Health Impacts
- Pancreatic and Hepatic Oncology Research
- Influenza Virus Research Studies
- Metabolism, Diabetes, and Cancer
- Nutrition, Genetics, and Disease
- Intergenerational Family Dynamics and Caregiving
- Cancer Risks and Factors
- Diet and metabolism studies
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
- Chronic Disease Management Strategies
- Health, Environment, Cognitive Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease and Transplantation
- Health Promotion and Cardiovascular Prevention
- Cancer, Lipids, and Metabolism
- Cardiovascular Disease and Adiposity
- Obesity, Physical Activity, Diet
Peking University
2019-2025
King University
2025
Johns Hopkins University
2015-2024
Guangxi University
2024
Ministry of Education of the People's Republic of China
2024
Ministry of Education
2024
Nanjing University of Aeronautics and Astronautics
2023
University of Oxford
2017-2022
China National Center for Food Safety Risk Assessment
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Abstract Aims The potential difference in the impacts of lifestyle factors (LFs) on progression from healthy to first cardiometabolic disease (FCMD), subsequently multimorbidity (CMM), and further death is unclear. Methods results We used data China Kadoorie Biobank 461 047 adults aged 30–79 free heart disease, stroke, diabetes at baseline. Cardiometabolic was defined as coexistence two or three CMDs, including ischaemic (IHD), type 2 (T2D). multi-state model analyse high-risk LFs (current...
Few studies have assessed the relationship between multimorbidity patterns and mortality risk in Chinese population. We aimed to identify examined associations of number chronic diseases with among middle-aged older adults.We used data from China Kadoorie Biobank included 512,723 participants aged 30 79 years. Multimorbidity was defined as presence two or more 15 collected by self-report physical examination at baseline. were identified using hierarchical cluster analysis. Cox regression...
The prevalence of diabetes is increasing rapidly in China. However, evidence limited about its effects on chronic liver diseases and cancer. We examined the associations with cancer random plasma glucose (RPG) these among participants without Chinese adults possible interaction by hepatitis B virus (HBV) infection. prospective China Kadoorie Biobank recruited 512,891 adults. During 10 years follow‐up, 2,568 cancer, 2,082 cirrhosis, 1,298 hospitalized nonalcoholic fatty disease (NAFLD), 244...
Low-temperature (LT) grown GaAs has a subpicosecond carrier response time that makes it favorable for terahertz photoconductive (PC) switching. However, this is obtained at the price of lower mobility and thermal conductivity than GaAs. Here we demonstrate sweep-out over an order magnitude higher sensitivity in detection from GaAs-based PC switch by using nanoplasmonic structure. As compared to conventional switch, observe 40 times peak-to-peak structure on The double commercial,...
Pre-symptomatic infection cases are those in which is detected before the person develops symptoms.Pre-symptomatic transmission defined as that occurs during pre-symptomatic phase of viral incubation period. 3
Evidence from epidemiological studies remains inconsistent or limited about the associations of tea consumption with incident diabetes and risk diabetic complications death among patients diabetes.
Evidence is sparse and inconclusive on the association between long-term fine (≤2.5 μm) particulate matter (PM
Background Little prospective evidence exists about risk factors and prognosis of acute pancreatitis in China. We examined the associations certain metabolic lifestyle with Chinese adults. Methods findings The China Kadoorie Biobank (CKB) recruited 512,891 adults aged 30 to 79 years from 5 urban rural areas between 25 June 2004 15 July 2008. During 9.2 follow-up (to 1 January 2015), 1,079 cases were recorded. Cox regression was used estimate adjusted hazard ratios (HRs) for associated...
Obesity is associated with a higher risk of cardiovascular disease (CVD), but little known about the role that circulating protein biomarkers play in this association.To examine observational and genetic associations adiposity proteins incident CVD.This subcohort study included 628 participants from prospective China Kadoorie Biobank who did not have history cancer at baseline. The Olink platform measured 92 markers baseline plasma samples. Data were collected June 2004 to January 2016...
Abstract Epigenetic clocks based on DNA methylation have been known as biomarkers of aging, including principal component (PC) representing the degree aging and DunedinPACE pace aging. Prior studies shown associations between epigenetic T2DM, but results vary by age metrics people. This study explored T2DM or glycemic traits, 1070 twins (535 twin pairs) from Chinese National Twin Registry. It also temporal relationships traits in 314 (157 who participated baseline follow‐up visits after a...
Cardiac troponin T (cTnT) is suggested as a predictor of amputation in patients with peripheral artery disease (PAD). However, cTnT-PAD association has not been systematically studied large study. This study evaluated the high-sensitivity cTnT (hs-cTnT) PAD incidence and also explored whether natriuretic peptide (NT-proBNP), another representative cardiac marker, predicts risk.
DNA methylation clocks emerged as a tool to determine biological aging and have been related mortality age-related diseases. Little is known about the association of age (DNAm age) with coronary heart disease (CHD), especially in Asian population.
Tuberculosis, caused by
Diabetes is associated with higher risk of colorectal cancer (CRC). Uncertainty remains about the relevance duration diabetes and association blood glucose CRC among individuals without diabetes.The prospective China Kadoorie Biobank recruited 512 713 participants in 2004-2008 from 10 diverse areas China. After years follow-up, 3024 incident cases (1745 colon, 1716 rectal) were recorded 510 136 prior at baseline. Cox regression was used to estimate adjusted HRs for (previously diagnosed or...
Central adiposity is associated with liver cancer risk beyond general in Western populations. However, there little prospective evidence East Asian populations who are more likely to have central at given BMI levels. The China Kadoorie Biobank recruited 512,713 adults aged 30-79 years from 10 diverse areas. During follow-up, 2,847 incident cases of were identified. Cox regression was used estimate adjusted hazard ratios (HR) for adiposity, excluding individuals cancers and diseases baseline...
<h3>Background and Objectives</h3> Contemporary cardiovascular disease (CVD) risk prediction models are rarely applied in routine clinical practice China due to substantial regional differences absolute risks of major CVD types within China. Moreover, the inclusion blood lipids most also limits their use Chinese population. We developed 10-year excluding that may be applicable diverse regions <h3>Methods</h3> derived sex-specific separately for ischemic heart (IHD), stroke (IS), hemorrhagic...
The metabolic mechanism of harmful effects red meat on the cardiovascular system is still unclear. objective present study to investigate associations self-reported consumption with plasma markers, and these markers risk diseases (CVD).Plasma samples 4,778 participants (3,401 CVD cases 1,377 controls) aged 30-79 selected from a nested case-control based China Kadoorie Biobank were analyzed by using targeted nuclear magnetic resonance quantify 225 metabolites or derived traits. Linear...