A5003990489- Hypothalamic control of reproductive hormones
- Neurological disorders and treatments
- Sperm and Testicular Function
- Reproductive biology and impacts on aquatic species
- Reproductive Biology and Fertility
- Immune cells in cancer
- Genetic Neurodegenerative Diseases
- Parkinson's Disease Mechanisms and Treatments
- Extracellular vesicles in disease
- Neuropeptides and Animal Physiology
- Immune Cell Function and Interaction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Atrial Fibrillation Management and Outcomes
- Reproductive Physiology in Livestock
- Obsessive-Compulsive Spectrum Disorders
- Ovarian function and disorders
- Cerebrovascular and Carotid Artery Diseases
- Neuroscience and Neuropharmacology Research
- Animal Behavior and Reproduction
- Hepatocellular Carcinoma Treatment and Prognosis
- Stress Responses and Cortisol
- Plant and animal studies
University of Florida
2020-2025
Xinjiang Medical University
2025
State Ethnic Affairs Commission
2024-2025
Southwest Minzu University
2024-2025
First Affiliated Hospital of Xinjiang Medical University
2025
Sun Yat-sen University
2023-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Nanjing University of Chinese Medicine
2021-2024
Shandong First Medical University
2023
Umeå University
2023
Exosomes can mediate a dynamic method of communication between malignancies, including those sequestered in the central nervous system and immune system. We sought to determine whether exosomes from glioblastoma (GBM)-derived stem cells (GSCs) induce immunosuppression. report that GSC-derived (GDEs) have predilection for monocytes, precursor macrophages. The GDEs traverse monocyte cytoplasm, cause reorganization actin cytoskeleton, skew monocytes toward suppresive M2 phenotype, programmed...
Glioblastoma multiforme (GBM), the most aggressive brain cancer, recurs because glioblastoma stem cells (GSCs) are resistant to all standard therapies. We showed that GSCs, but not normal astrocytes, sensitive lysis by healthy allogeneic natural killer (NK) in vitro. Mass cytometry and single-cell RNA sequencing of primary tumor samples revealed GBM tumor-infiltrating NK acquired an altered phenotype associated with impaired lytic function relative matched peripheral blood from patients or...
The mesencephalic (or midbrain) locomotor region (MLR) was first described in 1966 by Shik and colleagues, who demonstrated that electrical stimulation of this induced locomotion decerebrate (intercollicular transection) cats. pedunculopontine tegmental nucleus (PPT) cholinergic neurons midbrain extrapyramidal area (MEA) have been suggested to form the neuroanatomical basis for MLR, but direct evidence role these structures behavior has lacking. Here, we tested hypothesis MLR is composed...
Deep brain stimulation (DBS) is the most common surgical treatment for essential tremor (ET), yet there variation in outcome and targets. This study seeks to consolidate proposed "sweet spots," as well assess value of structural connectivity predicting outcomes.Ninety-seven ET individuals with unilateral thalamic DBS were retrospectively included. Using normative connectomes, measures correlated percentage improvement contralateral tremor, based on Fahn-Tolosa-Marin rating scale (TRS), after...
Abstract Circadian rhythms have been shown in the subthalamic nucleus (STN) Parkinson’s disease (PD), but only a few studies focused on globus pallidus internus (GPi). This retrospective study investigates GPi circadian large cohort of subjects with PD (130 recordings from 93 subjects) activity chronically recorded their home environment. We found significant change between daytime and nighttime most (82.4%), reduction at 56.2% an increase 26.2%. higher frequency bands ( > 20 Hz) was more...
Using the RIA for measuring serum testosterone (T) levels and mouse interstitial cell bioassay monkey LH, we studied secretory dynamics of these hormones in adult male monkey. Eight sexually mature monkeys species Macaca fascicularis were sedated blood was sampled under various protocols over 24 h. All experiments conducted between February June. A pronounced diurnal rhythm concentration T revealed by measurements from individual means summed 4-h morning evening intervals (0700–1100...
Abstract The Xinjiang Uyghur Autonomous Region of the People’s Republic China has been influenced by its natural ecological environment, historical evolution, and cultural customs since ancient times. aim this study was to investigate new genes that contribute lipid metabolism regulation in Han Chinese youth region through sequencing analysis. Based on threshold value triglycerides (TG), we selected two groups university students, namely, individuals with extremely low TG levels normal...
Semen cryopreservation is a crucial method for preserving genetic resources and accelerating the breeding process in domestic animals. However, frozen-thawed often leads to physical chemical damage semen, resulting oxidative stress that diminishes sperm vitality fertilization potential. This study aimed explore effects of docosahexaenoic acid (DHA) on quality yak semen. samples were collected from six healthy adult Maiwa yaks cryopreserved liquid nitrogen using extenders with varying DHA...
of 7 -23 in premature infants birth weight less than 1,500 g.They rose rapidly with the establishment respiration to normal newborn levels.
Neutrophil to lymphocyte ratio (NLR) is an inflammatory biomarker that has a close relationship with tumor progression and metastasis. In this study, we aimed investigate the role of NLR in prognosis male candidates hepatocellular carcinoma (HCC) undergoing liver transplantation (LT).We analyzed clinical data 248 HCC who underwent LT our Liver Transplantation Center between 2002 2012. All risk factors were by univariate multivariate Cox analysis survival rates calculated Kaplan-Meier...
Patients with advanced Alzheimer's disease (AD) experience cognitive impairment and physical disabilities in daily life. Currently, there are no treatments available to slow down the course of disease, limited exist only treat symptoms. However, deep brain stimulation nucleus basalis Meynert (NBM-DBS) has been reported improve function individuals AD. Here, we report effects NBM-DBS on a subject severe An 80-year-old male AD (Clinical Dementia Rating scale: 3.0 points) underwent surgery for...
Various parameters of copulatory behavior were examined in intact and castrated testosterone-(T-)treated male rats various ages ranging from 3 to 27 months. Serum T levels controlled by subcutaneous implantation different sizes T-filled Silastic capsules at the time castration. In rats, scores declined gradually middle age no ejaculation was observed any over 22 months age. When serum maintained 0.78–0.87 ng/ml for 6 4 age, these showed same activity as except that fewer exhibited 8 10...
Background: Patellar resurfacing after routine arthroplasty remains controversial. Few studies have specifically examined the effect of patellar on outcomes resection distal part femur and reconstruction with a megaprosthesis. Our objective was to compare megaprosthesis reconstructions without femoral tumor. Methods: We retrospectively reviewed clinical records patients tumor who underwent endoprosthetic between 1993 2013. excluded had extra-articular knee resection, patellectomy, revision,...
The levels of cellular components in each region the domestic fowl (Gallus domesticus) oviduct at various stages a reproductive cycle (developing, laying, and regressing) were compared. There differential growth patterns (infundibulum, magnum, isthmus, uterus, vagina) during cycle. magnum weight, relative to other regions oviduct, increased most rapidly development growth, decreased similar manner regression oviduct. Development primarily associated with hyperplasia (increase total DNA),...