A5031017577- Optical Network Technologies
- Advanced Photonic Communication Systems
- Photonic and Optical Devices
- Cancer-related molecular mechanisms research
- Heme Oxygenase-1 and Carbon Monoxide
- Autophagy in Disease and Therapy
- Inflammasome and immune disorders
- Semiconductor Lasers and Optical Devices
- Synthesis and Biological Evaluation
- Renal cell carcinoma treatment
- Optical Wireless Communication Technologies
- Indoor Air Quality and Microbial Exposure
- Glycosylation and Glycoproteins Research
- Advanced machining processes and optimization
- Carbohydrate Chemistry and Synthesis
- Proteoglycans and glycosaminoglycans research
- Pharmacogenetics and Drug Metabolism
- Advanced Machining and Optimization Techniques
- Advanced Surface Polishing Techniques
- Air Quality and Health Impacts
- Advanced Chemical Sensor Technologies
- Ferroptosis and cancer prognosis
- Nephrotoxicity and Medicinal Plants
- Advanced Battery Technologies Research
- NF-κB Signaling Pathways
Henan Provincial People's Hospital
2020-2025
Zhengzhou University
2020-2025
Henan University
2025
Anhui Polytechnic University
2024
Fudan University Shanghai Cancer Center
2020
Fudan University
2019
Dalian Institute of Chemical Physics
2014-2018
Chinese Academy of Sciences
2014-2018
University of Chinese Academy of Sciences
2016-2018
Tobacco Research Institute
2016-2018
Distant metastasis is the major cause of clear cell renal carcinoma (ccRCC)-associated mortality. However, molecular mechanisms involved in ccRCC remain to be fully understood. With increasing appreciation role long non-coding RNAs (lncRNAs) cancer development, progression, and treatment resistance, list aberrantly expressed lncRNAs contributing pathogenesis expanding rapidly.Bioinformatics analysis was carried out interrogate publicly available datasets. In situ hybridization qRT-PCR assays...
Sialylated N-glycans play pivotal role in several important biological and pathological processes. Their sialyl-linkage isomers, mostly α-2,3- α-2,6-linked, act differently during the cellular events diseases. While mass spectrometry (MS) technology is a powerful tool N-glycome analysis, it still suffers from an inability to distinguish linkage isomers of native N-glycans. Herein, we described sequential selective derivatization method, by which α-2,6- α-2,3-linked sialic acids are...
Background: Acute kidney injury (AKI) is a common postoperative event. Previous research suggests that intraoperative hypotension (IOH) associated with AKI. This connection, however, has not been studied in patients undergoing pancreaticoduodenectomy. Methods: Based on retrospective cohort study, we analyzed 844 adult who had pancreaticoduodenectomy between December 2016 and June 2020 Henan Provincial People's Hospital. We graphically modeled the associations lowest systolic diastolic...
Immunotherapy has revolutionized the treatment of clear cell renal carcinoma (ccRCC). However, therapy is constrained by drug resistance. Therefore, further characterization immune infiltration in ccRCC needed to improve its efficacy.Here, we adopted CIBERSORT method analyze level 22 cells, and analyzed correlation cells clinical parameters The Cancer Genome Atlas. We used consensus clustering cluster identified differently expressed genes (DEGs) between hot cold tumors using "Limma"...
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is considered to be the most carcinogenic of four tobacco-specific nitrosamines (TSNAs) and it needs metabolically activated exert its effect on humans. For simultaneous intake NNK other compounds with similar molecular structures in context tobacco smoke, whether (R,S)-N-nitrosoanatabine (NAT), (R,S)-N-nitrosoanabasine (NAB) nicotine contribute inhibitory potency cytochrome P450 (CYP) enzyme-catalyzed metabolism or not investigated. In...
Aristolochic acid (AA) exposure is a severe public health concern worldwide. AAs damage the kidney with an inevitable acute phase that similar to injury (AKI). Gasdermin E (GSDME) abundant in kidney; thus; it-mediated pyroptosis might be essential connecting cell death and inflammation promoting AAs-AKI. However, role exact mechanism of AAs-AKI have not been investigated. In this study, aristolochic I (AAI) was used establish AKI models. The expression translocation results showed...
Crotonaldehyde is a ubiquitous air pollutant in the environment. It reported to be harmful biosystems vivo and vitro. The exposure crotonaldehyde irritates mucous membranes induces edema, hyperemia, cell necrosis, inflammation, acute respiratory distress syndrome lungs. However, effects of on immune system have not been reported. In present study, 6-8 weeks old male Wistar rats were exposed by intratracheal instillation at doses 4, 8, 16 μL/kg body weight (b.w.). general damage animals was...
This article uses real parameters of a domestic conventional heavy trucks for basic dates, using Solidworks software as 3D platform, the structure model full floating cab air suspension system is designed and created, imported into ADAMS to simulate analyze, importantly analysis natural vibration frequency vehicle system. Through change damping coefficient lateral deoscillator in back system, function analyzed at same time. At last ride comfort test sample car on road, root mean square...
We propose a communication system of Circular Polarization Shift Keying (CPolSK) with homodyne coherent detection in free-space optical (FSO) Gamma-Gamma atmospheric turbulence channel. The need no polarization coordinate alignment, thus the complexity is reduced. Meanwhile, we derived closed bit error rate (BER) expression compared on-off keying (OOK) system. Simulation results show that CPolSK highly insensitive to phase noise and BER performance greatly promoted OOK modulation,...
Crotonaldehyde, a highly toxic α, β-unsaturated aldehyde, is major component of cigarette smoke and ubiquitous environmental pollutant. Crotonaldehyde exposure known to have adverse effects on respiratory health, but the underlying mechanisms remain obscure. As alveolar macrophages display important immunological inflammatory properties in response extraneous substances lung, we aimed at gaining more insight changes human macrophage-like cells transcriptome crotonaldehyde. In vitro cultures...
Carbon fiber reinforced polymer (CFRP) has obtained the widespread use in significant basic parts owing to its excellent properties. Different methods including conventional PCD tool using dry machining (CPD), with CO 2 cryogenic cooling (CPC), and textured (TPC), were introduced investigated their effects on holes-making performance. Results demonstrated that average entrance diameter relative error of different spindle speeds CPC about 4001 4005.4 μm 0.025% 0.65%, respectively. Dimensional...
In this paper, we mainly introduce a novel measurement system of the polarization extinction ratio(PBSBC system). Here, because main optical components is PBS and PBC, so call PBSBC system. First all, principle method measuring ratio by drawing circle on Poincare. Secondly, present block diagram system, design an experimental to theoretically experimentally investigate performance though multiple groups data collected under same condition. Finally, could show that it compatible with analysis in
As a key component of the subcarrier-based optical phase-locked loop, an voltage controlled oscillator (OVCO) suffers penalty due to various factors, such as nonoptimal peak drive voltage, bias deviation, and inevitable imperfections modulator driver. We have performed systematic study investigate influence these factors on performance OVCO. Our theoretical analysis experimental demonstration show that by setting around 1.172Vπ, employing proper automatic control technology for Mach–Zehnder...
Get PDF Email Share with Facebook Tweet This Post on reddit LinkedIn Add to CiteULike Mendeley BibSonomy Citation Copy Text D. Ding, Y. 'a. Zhang, Huang, and L. Wang, "A Wide Pull-in Range OPLL System Using an Optical Voltage Controlled Oscillator," in Asia Communications Photonics Conference 2015, C. Lu, J. Luo, Ji, K. Kitayama, H. Tam, Xu, P. Ghiggino, N. Wada, eds., OSA Technical Digest (online) (Optica Publishing Group, 2015), paper AM2H.3. Export BibTex Endnote (RIS) HTML Plain alert...
In this paper the rotating ultrasonic drilling is discussed as a new machining method to machine micro hole. It considerably improved problems such low entering positioning accuracy, inferior hole dimensional accuracy and surface quality in current method. The characteristics further proved important meaning of research drilling. Due movement introduced drilling, there are many technologies that worth study. This mainly how component composite horn achieves resonance under different...
A novel solution of frequency locking based on beat detection in homodyne coherent receiver is presented and experimentally demonstrated. The detection, using two signals generated by a balance detector module, easily to eliminate the noise introduced during long distance transmission. Furthermore, FPGA, as core control unit, adopted change resulting OVCO basis deviation. proposed scheme tested more efficiency higher stability than previously single path feedback loop.
We propose a detection scheme called Stokes vector direct (SV-DD) to realize high electrical spectral efficiency and cost-effective optical communication , which is more suitable than coherent for short-reach. At reception, the signal detected in space.SV-DD different from conventional DD technique parts of not requiring polarization tracking or narrow band filtering carrier extraction. 2nd-order nonlinearity due photodetection fundamental limitation DD. The SV-DD systems use 2*4 coupler...