A5060227550- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Alcohol Consumption and Health Effects
- Hepatitis C virus research
- Nutrition and Health in Aging
- COVID-19 Clinical Research Studies
- Renal Transplantation Outcomes and Treatments
- SARS-CoV-2 and COVID-19 Research
- Liver Diseases and Immunity
- Hepatitis Viruses Studies and Epidemiology
- Long-Term Effects of COVID-19
- Hepatocellular Carcinoma Treatment and Prognosis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Bariatric Surgery and Outcomes
- Diversity and Career in Medicine
- Diet and metabolism studies
- Global Health Workforce Issues
- Healthcare Policy and Management
- Multiple and Secondary Primary Cancers
- Cancer, Lipids, and Metabolism
- Body Composition Measurement Techniques
- Metabolism and Genetic Disorders
- COVID-19 and healthcare impacts
- Cardiovascular and Diving-Related Complications
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2022-2025
University Hospital of Bern
2019-2024
University of Bern
2020-2024
Kantonsspital Baselland
2023
University of Basel
2023
Center for Pediatric Endocrinology Zurich
2022-2023
University of Padua
2017-2022
University of Brescia
2020
Creative Research Enterprises (United States)
2018
Knowledge on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in liver transplant recipients is lacking, particularly terms of severity the disease. The aim this study was to describe demographic, baseline clinical characteristics and early outcomes a European cohort with SARS-CoV-2 infection.We conducted an international prospective across Europe confirmed by microbiological assay during first outbreak COVID-19 pandemic. Baseline characteristics, presentation,...
There is limited information on the effects of statins outcomes liver transplantation (LT), regarding either their use by LT recipients or donors.
Porto-sinusoidal vascular liver disorder (PSVD) is a rare disease that occasionally requires transplantation (LT), despite usually presenting preserved function. There remains paucity of data pertaining to LT in PSVD. The aim was identify features associated with post-LT outcomes PSVD.Retrospective multicentre study 79 patients who received for PSVD.Median follow-up 37 (range 1-261) mo. Refractory ascites 24 (30%), hepatic encephalopathy 16 (20%), and hepatopulmonary syndrome 13 (16.3%) were...
Introduction: The use of direct-acting antivirals (DAAs) has drastically changed the management HCV-infected patients by achieving a 95–98% sustained virologic response (SVR) and reducing morbidity mortality in this population. However, despite their effectiveness, controversy exists concerning occurrence oncologic events following DAA therapy. Aims Methods: A retrospective analysis was conducted on data from Swiss Hepatitis C Cohort Study, prospective cohort involving with positive HCV...
Patients with severe alcoholic hepatitis SAH may suffer of undiagnosed psychiatric illnesses, typically depression. Assessment prevalence and potential impact disturbances on alcohol relapse after LT, were the main objectives this study. One hundred consecutive patients from April 2016 to May 2023 analyzed. All evaluated by an integrated team including psychiatrists, addiction specialists social workers. Thirty (30%) listed, whom 25 underwent early liver transplantation (eLT) a median time...
Metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated (ALD) are among the leading indications for transplantation (LT). The definition of metabolic dysfunction- (MetALD) identifies individuals with MASLD who consume moderate levels alcohol, representing a severe phenotype within (SLD) spectrum. Patients MetALD face higher risks post-LT complications, including syndrome, graft steatosis, fibrosis. Despite rising prevalence due to increasing obesity alcohol...
Frailty is frequent in cirrhosis and associated with skeletal muscle abnormalities worse prognosis. 2D shear-wave elastography (2D-SWE) could mirror biomechanical properties of reflecting quality. However, there no data on 2D-SWE stiffness assessment frailty.Outpatients were prospectively included a single center. Skeletal was studied at the rectus femoris by 2D-SWE. Ileo-psoas area index (area/height2), antero-posterior diameter (RF) measured ultrasound.We 44 patients (24 male, age 59 [IQR...
Abstract Background Non-alcoholic fatty liver disease is rapidly emerging as the leading global cause of chronic disease. Efficient management requires low-cost, non-invasive techniques for diagnosing hepatic steatosis accurately. Here, we propose quantifying speed sound (SoS) with computed ultrasound tomography in echo mode (CUTE), a recently developed imaging modality adapted to clinical pulse-echo systems. CUTE reconstructs spatial distribution SoS by measuring local phase shifts when...
Immunosuppressive agents are known to interfere with T and/or B lymphocytes, which required mount an adequate serologic response. Therefore, we aim investigate the antibody response SARS-CoV-2 in liver transplant (LT) recipients after COVID-19.Prospective multicentre case-control study, analysing antibodies against nucleocapsid protein, spike (S) protein of and their neutralising activity LT confirmed infection (COVID-19-LT) compared immunocompetent patients (COVID-19-immunocompetent)...