Can Gönen

ORCID: 0000-0002-8882-9272
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal disorders and treatments
  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Microscopic Colitis
  • Gastrointestinal Tumor Research and Treatment
  • Gallbladder and Bile Duct Disorders
  • Eosinophilic Esophagitis
  • Esophageal and GI Pathology
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Infective Endocarditis Diagnosis and Management
  • Drug-Induced Hepatotoxicity and Protection
  • Hematological disorders and diagnostics
  • Colorectal Cancer Screening and Detection
  • Lymphoma Diagnosis and Treatment
  • Vascular Malformations and Hemangiomas
  • Autoimmune and Inflammatory Disorders
  • Lymphatic Disorders and Treatments
  • Intensive Care Unit Cognitive Disorders

Goethe University Frankfurt
2023

Agaplesion Markus Hospital
2023

Acıbadem Adana Hospital
2020-2022

Kent Hastanesi
2020-2022

Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2011-2020

Dokuz Eylül University
2007-2016

Kocaeli Üniversitesi
2016

Gentofte Hospital
2012

University Gastroenterology
2007

Hacettepe University
2002-2006

Laurent Peyrin–Biroulet Jessica R. Allegretti David T. Rubin Brian Bressler Matthew Germinaro and 95 more Kuan-Hsiang Gary Huang Nicole Shipitofsky Hongyan Zhang Rebbecca Wilson Chenglong Han Brian G. Feagan William J. Sandborn Julián Panés Tadakazu Hisamatsu Gary R. Lichtenstein Bruce E. Sands Axel Dignaß О. Аbrahamovych Halyna Afanasieva Lilia Aitova Engin Altıntaş Romain Altwegg П. С. Андреев Kazuki Aomatsu Monika Augustyn Paola Balestrieri Jakob Begun Luciana Soledad Brunatto Diego Bulgheroni Elena Bunkova Mercedes Cabello Qian Cao Flavio Caprioli Rute Cerqueira Baili Chen Chou‐Chen Chen Chou-Pin Chen Cheng‐Tang Chiu Chang Hwan Choi Michele Cicala Olena Datsenko Pieter Dewint Eugeni Domènech Joris Dutré George Duvall J. C. Fernández Rafał Filip Ronald Fogel Sharyle Fowler Toshimitsu Fujii Masayuki Fukata Yohei Furumoto Antonio Gasbarrini Beata Gawdis-Wojnarska Cyrielle Gilletta Paolo Gionchetti Eran Goldin Oleksandr Golovchenko Maciej Gonciarz Can Gönen Gaston Gonzalez Segura Oleksii Gridnyev T Gyökeres Xavier Hébuterne Charlotte Hedin Per M. Hellström Ida Hilmi Ivo Horný Gyula Horvat Namiko Hoshi Luděk Hrdlička Shunji Ishihara Olha Ivanishyn Byung Ik Jang Odery Ramos Takashi Kagaya Shuji Kanmura Marina Karakina Nakai Katsuhiko Jarosław Kierkuś Hyo Jong Kim Tae Oh Kim Young‐Ho Kim G Kiss Jochen Klaus D Kleczkowski Maria Kłopocka Taku Kobayashi Iwona Kobielusz‐Gembala Ja Seol Koo Adam Kopoń Tetiana Kravchenko Masatoshi Kudo Kwang An Kwon Paula Lago David Laharie Ian C. Lawrance Jarosław Leszczyszyn Yan Li Milan Lukáš

The QUASAR Phase 2b Induction Study evaluated the efficacy and safety of guselkumab, an interleukin-23p19 subunit antagonist, in patients with moderately to severely active ulcerative colitis (UC) prior inadequate response and/or intolerance corticosteroids, immunosuppressants, advanced therapy.

10.1053/j.gastro.2023.08.038 article EN cc-by Gastroenterology 2023-09-01

In many countries, gastric cancer is not diagnosed until an advanced stage. An Internet-based e-learning system to improve the ability of endoscopists diagnose at early stage was developed and evaluated for its effectiveness.The study designed as a randomized controlled trial. After receiving pre-test, participants were randomly allocated either or non-e-learning group. Only those in group gained access system. Two months after both groups received post-test. The primary endpoint difference...

10.1016/j.ebiom.2016.05.016 article EN cc-by EBioMedicine 2016-05-17

Abstract Background: It has been shown that standard endoscopic features often labeled as gastritis a poor correlation with histopathology. Recently, high resolution magnifying endoscopy reported to be an effective method diagnose gastritis. The aim of the present study was compare for diagnosis Helicobacter pylori gastritis, and determine whether can diagnosed based on findings at magnification endoscopy. Materials Methods: A total 129 patients were enrolled into study. Erythema, erosions,...

10.1111/j.1523-5378.2009.00650.x article EN Helicobacter 2009-01-15

INTRODUCTION: Risk stratification based on biochemical variables is a useful tool for monitoring ursodeoxycholic acid (UDCA)-treated patients with primary biliary cholangitis (PBC). Several UDCA response criteria and scoring systems have been proposed risk prediction in PBC, but these not validated large external cohorts. METHODS: We performed study data of 1746 UDCA-treated PBC from 25 centers Europe, United States, Canada. The prognostic performance the (GLOBE UK-PBC) (Barcelona, Paris I,...

10.14309/ajg.0000000000000290 article EN The American Journal of Gastroenterology 2019-06-19

Anti-tumor necrosis factor alpha (TNF-α) inhibitors are effective in the treatment of various inflammatory rheumatic conditions.Increased risks serious infections major issues concerning long-term safety these agents.We present a case young male Behcet's patient whose disease was complicated by cytomegalovirus (CMV) colitis.Colitis started 10 d after third Infliximab dose and responded to cessation TNF blocking administration ganciclovir.Tumor interferon gamma act at several levels combating...

10.3748/wjg.14.2912 article EN cc-by-nc World Journal of Gastroenterology 2008-01-01

Objective The aim of the study was to compare haemodynamic responses, recovery and discharge times, physician satisfaction etomidate–remifentanil propofol–remifentanil combinations in patients undergoing elective colonoscopy. Methods Sixty patients, aged 18–65 years, scheduled for colonoscopy under sedation were prospectively randomized, double blind study. Two minutes after beginning a continuous remifentanil infusion (0.1 μg kg−1 min−1), etomidate or propofol administered. Patients group...

10.1097/eja.0b013e328318c666 article EN European Journal of Anaesthesiology 2009-05-01

Objective The role of routine endoscopic duodenal biopsies obtained during the evaluation iron deficiency anaemia is being increasingly emphasized, but insufficiently applied. Diagnostic yield this practice, mainly identification coeliac disease, differs in different populations and geographic regions. aim study to assess usefulness upper endoscopy patients presenting with Western Anatolia. Methods Routine were evaluated over a 12-month period 100 consecutive adult undergoing endoscopy. All...

10.1097/01.meg.0000250583.07867.b7 article EN European Journal of Gastroenterology & Hepatology 2007-01-01

Aim. To provide a simple fibrosis index combining the routine laboratory markers for predicting significant (SF) and cirrhosis in patients with chronic HCV. Methods. Platelet count, ALT, AST, AST to ALT Ratio, Ratio Index (APRI), Forns index, FIB-4 Age of 202 liver biopsy performed HCV-infected were reviewed. METAVIR classification was used determine stage fibrosis. The predictive constructed by multiple linear regression analysis (− 2.948 + 0.562 × 0.288 APRI 0.006 platelet count [109/L])....

10.3109/00365513.2013.879392 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2014-01-24

Helicobacter pylori remains one of the most common bacterial infections worldwide. Clarithromycin resistance is important cause H. eradication failures. Effective antibiotic therapies in infection must be rapidly adapted to local patterns. We investigated prevalence clarithromycin due mutations positions 2142 and 2143 23SrRNA gene by fluorescence situ hybridisation (FISH), compared with culture antimicrobial susceptibility testing 234 adult patients dyspepsia who were enrolled. Antrum corpus...

10.1002/cjp2.57 article EN cc-by-nc-nd The Journal of Pathology Clinical Research 2016-08-18

SummaryA decision-analysis model was constructed to assess total direct health care costs of four current first-line treatment options for mild-to-moderate bleeding episodes in haemophilia patients with inhibitors Turkey: recombinant activated Factor VII (rFVIIa); high-dose VIII; prothrombin complex concentrate (PCC); and PCC (aPCC). Resource utilisation based on a retrospective analysis 105 treated during the period January 1996 December 2002. Clinical outcomes were derived from combination...

10.3111/200508046054 article EN Journal of Medical Economics 2005-01-01

The aim of this study is to assess the frequency and clinical characteristics cytosine arabinoside-induced fever in patients with acute myeloid leukemia remission, receiving high-dose (3 g/m2) consolidation therapy. We have investigated 77 cycles over a period 4 years. A strict definition (i.e. without neutropenia negative blood cultures during episodes) was used. Of cycles, due cytarabine detected 33 (43%). Median time onset from beginning first chemotherapy dose 22 h maximum temperature...

10.1097/00001813-200501000-00008 article EN Anti-Cancer Drugs 2004-12-17

Abstract: Herpes simplex virus (HSV) causes life‐threatening infections in immunocompromised patients such as transplant recipients and with hematologic malignancies. We herein describe the case of a patient chronic myeloid leukemia blastic transformation who developed severe herpetic tonsillitis complicated by tonsillar abscess formation. Abscess formation was determined computed tomography, whereas due to HSV confirmed pathologic immunohistochemical examinations biopsy. For molecular...

10.1111/j.1399-3062.2006.00131.x article EN Transplant Infectious Disease 2006-08-04

Background . To investigate the relationship between DR-70 serum levels and dysplastic colon polyps. Materials Methods A total of 130 patients with adenomatous polyps detected by colonoscopy divided into two groups including low versus high grade polyp, along 50 healthy blood donors were included in study. Blood samples from each participant analyzed for CEA levels. Results No statistically significant differences observed terms age or gender. The median level was 0.5 μ g/mL control group...

10.1155/2013/275392 article EN cc-by Gastroenterology Research and Practice 2013-01-01

The treatment of gastroesophageal junction tumors remains controversial due to confusion on whether they should be considered as primary esophageal or gastric tumors. incidence these with poor prognosis has increased, thus creating scientific interest cancers. Esophagogastric cancers are classified according their location by Siewert, and the each type varies. We evaluated prognostic factors differences in clinicopathologic patients tumor, who have been treated followed-up our clinics.We...

10.5152/ucd.2017.3379 article EN Turkish Journal of Surgery 2017-03-24

Intestinal ultrasound (IUS) is a valid cross-sectional imaging technique for the evaluation of Crohn's disease (CD). With advancements in technology, portable systems are becoming widely available, and inevitable change to their use by non-radiologist clinicians would be valuable contribution improving patient care. This study aimed investigate diagnostic yield IUS examination performed gastroenterologist with system as an adjunct modality routine care CD patients.A total 117 patients were...

10.1093/gastro/goaa088 article EN cc-by-nc Gastroenterology report 2020-11-06

There is increasing interest in noninvasive tests for the assessment of Helicobacter pylori infection, and urine-based have been widely used as to detect infection. The aim this study was evaluate adaptation usefulness urine antibody enzyme-linked immunosorbent assay card clinical setting anti-Helicobacter IgG excreted into Turkish adult patients with dyspepsia.One-hundred twenty-four who were admitted referred upper endoscopy Dokuz Eylül University Hospital, Gastroenterology Clinic studied....

10.4318/tjg.2012.0497 article EN The Turkish Journal of Gastroenterology 2012-12-01

Celiac artery (CA) stenosis is a relatively common finding in patients undergoing pancreaticoduodenectomy (PD). In the presence of CA stenosis, arterial blood supply to celiac territory usually sustained from superior mesenteric (SMA) through well-developed collaterals. this paper, authors report endosonographically identified prominent gastroduodenal as sign for first time. Uncovering previously unidentified vascular abnormality, endoscopic ultrasound (EUS) has improved patient management....

10.4103/2303-9027.191674 article EN Endoscopic Ultrasound 2016-01-01
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