A5006949278- Advanced biosensing and bioanalysis techniques
- Advanced Biosensing Techniques and Applications
- Sinusitis and nasal conditions
- Biosensors and Analytical Detection
- Head and Neck Surgical Oncology
- Organ Donation and Transplantation
- Allergic Rhinitis and Sensitization
- Renal Transplantation Outcomes and Treatments
- Photoacoustic and Ultrasonic Imaging
- Renal and Vascular Pathologies
- Lipoproteins and Cardiovascular Health
- Photodynamic Therapy Research Studies
- Cancer, Lipids, and Metabolism
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Insects and Parasite Interactions
- Medicinal plant effects and applications
- Ear and Head Tumors
- Anodic Oxide Films and Nanostructures
- Lipid metabolism and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Regional Development and Environment
- Marine Bivalve and Aquaculture Studies
- Soft tissue tumors and treatment
Seoul National University
2023-2024
Seoul National University Bundang Hospital
2024
Gachon University
2024
Gachon University Gil Medical Center
2024
Boramae Medical Center
2023-2024
Seoul Metropolitan Government
2024
Seoul National University Hospital
2020-2023
Jeju National University
2019-2021
Abbott (South Korea)
2020-2021
Korea University
2014-2021
This study investigated the clinical implications of neutrophil extracellular trap (NET) formation (NETosis) and eosinophil (EET) (EETosis) regarding refractoriness in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP).Nasal polyp specimens were obtained from 117 patients CRSwNP who received endoscopic sinus surgery. Disease control status at postoperative 1 year was assessed. Refractory cases defined as partly controlled or uncontrolled according to EPOS 2020 guidelines. NETosis...
<b><i>Background:</i></b> Cockroaches produce potent allergens, and cockroach feces are known to be especially rich in allergens. In this study, we analyze the allergenic components from evaluate allergenicity of recombinant α-amylase identified fecal extract. <b><i>Methods:</i></b> IgE-reactive proteins German extract were analyzed by proteomic analysis immunoblotting. Recombinant was produced its evaluated ELISA....
BACKGROUND AND OBJECTIVES: Bilirubin screening before discharge is performed to identify neonates at risk for future hyperbilirubinemia. The American Academy of Pediatrics recommends using a graph bilirubin levels by age (the Bhutani Nomogram) guide follow-up and different determine phototherapy recommendations. Our objective was evaluate predictive models that incorporate the difference between last total serum (TSB) threshold (Δ-TSB) predict postdischarge TSB above single graph. METHODS:...
Homozygous familial hypercholesterolemia (HoFH) is an ultra-rare disorder of lipid metabolism characterized by markedly increased levels low-density lipoprotein cholesterol (LDL-C), leading to risk early onset atherosclerotic cardiovascular disease (ASCVD) and premature death. To assess the real-world burden for patients with HoFH using healthcare claims data. Due lack International Classification Diseases, Tenth Revision diagnosis codes HoFH, cohort was formed two sources: prescription...
Fractional exhaled nitric oxide (FeNO) is useful in the management of asthma and predicting efficacy standard corticosteroids biologics. However, diagnostic value FeNO asthmatic chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear.We assessed levels patients CRSwNP evaluated for screening type 2 (T2-CRSwNP) asthma.We enrolled 94 who were diagnosed underwent functional endoscopic sinus surgery. levels, blood eosinophil percentage, total IgE, spirometry tests (FEV1/FVC),...
Chronic rhinosinusitis (CRS) is classified into type 2 (T2) and non-T2 inflammation. T2 CRS presents as a severe form, with nasal polyps (CRSwNP), which often occurs asthma comorbidity worldwide. Some cases of show polyposis refractoriness, mainly in Asian countries. However, its mechanism remains elusive. To investigate biomarker for the refractoriness CRSwNP via RNA sequencing.
The intramolecular fluorescence self-quenching phenomenon is a major drawback in developing high-performance fluorometric biosensors which use common fluorophores as signal generators. We propose two strategies involving liberation of the fluorescent molecules by means enzymatic fragmentation protein or dehybridization double-stranded DNA. In former, bovine serum albumin (BSA) was coupled with BODIPY dye (Red BSA), and then immobilized on solid surface. When insolubilized Red BSA treated...
Nationwide studies on the effects of wealth inequality kidney transplantation are rare, particularly in a country with an expanded National Health Insurance Service and Asian countries.In this nationwide, population-based cohort study, we reviewed national claims database Korea which details nationwide health insurance provided. From 2007 to 2015, 9 annual cohorts end-stage renal disease patients were included. The financial statuses collected stratified into 5 subgroups each year: aided...
Chitons are a group of marine mollusks (class Polyplacophora) characterized by having eight articulating shell plates on their dorsal body surface. They represent suitable materials for studying the spatiotemporal processes that underlie population differentiation and speciation in ocean environments. Here we performed genetic analyses northwestern Pacific chiton Acanthochitona cf. rubrolineata (Lischke, 1873) using two mitochondrial gene fragments (COI 16S) from 180 individuals sampled 11...
Mature cardiomyocytes (CMs) obtained from human pluripotent stem cells (hPSCs) have been required for more accurate in vitro modeling of adult-onset cardiac disease and drug discovery. Here, we found that FGF4 ascorbic acid (AA) induce differentiation BG01 embryonic cell-cardiogenic mesoderm (hESC-CMCs) into mature ventricular CMs. Co-treatment hESC-CMCs with FGF4+AA synergistically induced FGF4+AA-treated hESC-CMs robustly released acute myocardial infarction (AMI) biomarkers (cTnI, CK-MB,...
Label-free immunosensing based on the conformational change of CBP depending analyte concentration was explored for semi-continuous analysis Ca<sup>2+</sup>.
Background and Objectives: To assess whether the audiological clinical outcomes of type 0 tympanoplasty (T0) performed using cartilage were comparable with those ossiculoplasty in patients who underwent canal wall down mastoidectomy (CWDM).Subjects Methods: This study included had chronic otitis media cholesteatoma CWDM involving partial ossicular replacement prosthesis (PORP), total (TORP), or T0. Anatomical success rates hearing analyzed.Results: Seventy-two this study; 29 them T0, 27...
Introduction: Utilizing the endoscopic trans-sphenoidal approach (TSA) for anterior skull base procedures has demonstrated an impact on postoperative olfactory function. Age is acknowledged as a notable factor influencing recuperation following damage to organ. This study aims explore connection between age and recovery TSA, well investigate how histological features of epithelium interact with age-related after TSA.
The primary goal during cancer removal surgery is to completely excise the malignant tumor. Because color of tumor and surrounding tissues very similar, it difficult observe with naked eye, posing a risk damaging blood vessels process. Therefore, fluorescence emission induced using fluorescent contrast agent, classification monitored through camera imaging. LEDs must be irradiated generate electromotive force. However, power beam width LED are insufficient this force effectively, so...