A5100456690- Insect Resistance and Genetics
- Abdominal Surgery and Complications
- Clinical Nutrition and Gastroenterology
- Insect and Pesticide Research
- Nutrition and Health in Aging
- Gut microbiota and health
- Respiratory Support and Mechanisms
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Ferroptosis and cancer prognosis
- Alcohol Consumption and Health Effects
- Insect Pest Control Strategies
- Pediatric health and respiratory diseases
- Fatty Acid Research and Health
- Biochemical Acid Research Studies
- Genetic factors in colorectal cancer
- Mosquito-borne diseases and control
- Vitamin C and Antioxidants Research
- Horticultural and Viticultural Research
- Nutritional Studies and Diet
- Food composition and properties
- Medicinal Plant Pharmacodynamics Research
- Silk-based biomaterials and applications
- Advanced Glycation End Products research
Shandong Provincial Hospital
2024
Shandong University
2024
Ningbo Medical Center Lihuili Hospital
2017-2024
Xinxiang Medical University
2024
Shengli Oilfield Central Hospital
2024
Jiangsu Province Hospital
2024
Nanjing Medical University
2013-2024
Qingdao University
2020-2023
Second People’s Hospital of Huai’an
2020-2022
Xuzhou Medical College
2020-2022
In 2012, the European Society of Intensive Care Medicine proposed a definition for acute gastrointestinal injury (AGI) based on current medical evidence and expert opinion. The aim present study was to evaluate feasibility using AGI grading system investigate association between severity grades with clinical outcome in critically ill patients. Adult patients at 14 general intensive care units (ICUs) an expected ICU stay ≥24 h were prospectively studied. grade assessed daily basis (GI)...
Gut microbiota dysbiosis has adverse health effects on human body. Multi-drug-resistant tuberculosis (MDR-TB) treatment uses a variety of antibiotics typically for more than 20 months, which may induce gut dysbiosis. The aim this study is to investigate the long-term MDR-TB and its related consequences. A total 76 participants were recruited at hospital in Linyi, China. included one active group, recovered group from two treatment-naive groups as control. treatment-naïve constructed match...
Chronic excessive alcohol intake may lead to male reproductive damage. Lutein is a carotenoid compound with antioxidant activity. The purpose of this study was observe the effect lutein supplementation on damage caused by intake. In study, an animal model drinking (12 mL/(kg.bw.d)) for 12 weeks established and supplemented different doses (12, 24, 48 mg/(kg.bw.d)). results showed that body weight, sperm quality, sex hormones (FSH, testosterone), markers (GSH-Px) decreased significantly,...
To evaluate the protective effects of α-lipoic acid on kidneys Goto-Kakisaki (GK) diabetic rats, ten GK rats were randomly divided into a control group and lipoic acid-treated with 35 mg·Kg−1 intraperitoneal injections. Four healthy Wistar served as normal controls. Malonaldehyde (MDA), ascorbic (vitamin C), vitamin E, glutathione (GSH) superoxide dismutase (SOD) levels in renal homogenate, urine protein excretion measured. The expression mRNA for NF-κB, NADPH oxidase subunits p22phox...
Abstract Background The initialization of the neonatal gut microbiota (GM) is affected by diverse factors and associated with infant development health outcomes. Methods In this study, we collected 207 faecal samples from 41 infants at 6 time points (1, 3, 7 days 1, months after birth). were assigned to four groups according delivery mode (caesarean section (CS) or vaginal (VD)) feeding pattern (breastfeeding formula milk). Results meconium bacterial diversity was slightly higher in CS than...
Temozolomide (TMZ) is a widely utilized chemotherapy treatment for patients with glioblastoma (GBM), although drug resistance constitutes major therapeutic hurdle. Emerging evidence suggests that ferroptosis-mediated therapy could offer an appropriate alternative option against cancer cells are resistant to certain drugs. However, recurrent gliomas display robust ferroptosis resistance, the precise mechanism of remains elusive. In present work, we report proline rich protein 11 (PRR11)...
Abstract Background The 2012 European Society of Intensive Care Medicine (ESICM) guidelines provided a clear definition feeding intolerance (FI). study aimed to investigate the association between FI based on current ESICM and clinical outcome further explore effect duration mortality. Methods Adult patients from 14 general intensive care units (ICUs) with an expected ICU stay ≥24 hours were prospectively studied. Based in first week admission ICU, was categorized as 7‐day persistent...
Staphylococcus aureus is the most common cause of difficult-to-treat osteomyelitis (OM). To better diagnose and manage S. OM, especially for severe long duration cases, indicators risk prediction severity evaluation are needed. Here, 139 clinical isolates from orthopedic infection were divided into OM group (60 60 patients) non-OM (79 79 patients). Molecular types, antimicrobial susceptibility, virulence factor profiles evaluated compared between two groups to identify potential associated...
Inflammatory cytokines and metabolic abnormalities are common in patients with tuberculosis. Observational studies have indicated that probiotics modulate inflammatory metabolites; however, clinical evidence of the effect on tuberculosis is lacking. This study investigated effects Lactobacillus casei metabolites during treatment.A randomized controlled trial was conducted. A total 47 inpatients were included randomly assigned to receive standard antituberculosis therapy only (control group)...
Streptococcus pneumoniae (Spn) is a leading respiratory tract pathogen that colonizes the nasopharynx (NP) through adhesion to epithelial cells and immune evasion. Spn actively interacts with other microbiota in NP but nature of these interactions are incompletely understood. Using 16S rRNA gene sequencing, we analyzed composition children or without colonization. 96 were included study cohort. 74 samples when 6 months old 85 12 old. We found several genera correlated negatively positively...
<b><i>Background/Aims:</i></b> To examine the cross-sectional and longitudinal associations of serum ferritin levels with hyperuricemia. <b><i>Methods:</i></b> A subsequently prospective study was performed among employees Zhenhai Refining Chemical Company, Ningbo, China. In a study, association between prevalence hyperuricemia analyzed. Subjects who were free at baseline followed up annually to explore incidence....
Scope Probiotics are promising in mitigating drug‐induced liver injury animal experiments. However, the clinical evidence is absent. The objective to investigate effect of adjunctive Lactobacillus casei on tuberculosis‐drug‐induced injury. Methods and results A post hoc analysis conducted for a previous randomized controlled trial. trial registered at Chinese Clinical Trial Registry (No. ChiCTR‐IOR‐17013210). Four hundred twenty nine patients allocated receive standard tuberculosis therapy...
Studies were carried out to isolate chlorpyrifos degrading Bacillus thuringiensis (Bt) strains from chlorpyrifos‐contaminated samples. Six Bt (isolation rate 2.7%) isolated by modified sodium acetate antibiotic heat treatment, and one novel strain (BRC‐HZM2) was selected for further analysis. Phenotype phylogeny analysis of this conducted on the basis biochemical reactions, sensitivity, 16s rRNA genes, plasmid profile, insecticidal crystal protein profiles, PCR–RFLP cry cyt genes. The...
In addition to being used increasingly as a model system in modern molecular biology studies, the free-living nematode Caenorhabditis elegans (Maupas, 1900) is an important pathogen fungi and straw mushrooms. this study, Bacillus thuringiensis strain 010 was found have significantly detrimental activity against C. elegans. To further characterize activity, toxicological mechanism elucidated at level. Genes encoding for crystal protein chitinase were isolated, cloned, sequenced. However,...
Globally, Aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as vector for human diseases, such yellow fever, dengue, and chikungunya. To identify (1) transcriptomic basis midgut (2) key genes are involved in toxicity process by comparative analysis between control Bacillus thuringiensis (Bt) toxin (LLP29 proteins)-treated groups. Next-generation sequencing technology was used to sequence transcriptome A. aegypti. A total 17130 unigenes, including 574 new were...