A5100397817- Viral-associated cancers and disorders
- Tuberculosis Research and Epidemiology
- Cancer-related molecular mechanisms research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ferroptosis and cancer prognosis
- Evaluation and Optimization Models
- Winter Sports Injuries and Performance
- RNA modifications and cancer
- Helicobacter pylori-related gastroenterology studies
- Photonic and Optical Devices
- Photonic Crystals and Applications
- Digestive system and related health
- Mycobacterium research and diagnosis
- Evaluation Methods in Various Fields
- Diagnosis and treatment of tuberculosis
- Gastric Cancer Management and Outcomes
- Histiocytic Disorders and Treatments
- Terahertz technology and applications
- Fibroblast Growth Factor Research
- Lipid metabolism and disorders
- Hypertrophic osteoarthropathy and related conditions
- Thyroid Cancer Diagnosis and Treatment
- Optical Coatings and Gratings
- Dermatological and Skeletal Disorders
- Aortic Thrombus and Embolism
Qingdao University
2011-2024
Second Military Medical University
2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Xinjiang Production and Construction Corps
2024
Eastern Hepatobiliary Surgery Hospital
2024
Bengbu Medical College
2023
Wannan Medical College
2023
First Affiliated Hospital of Wannan Medical College
2023
Peking University First Hospital
2022
Background: Chloride channel 3 (CLCN3) is regulated by transcription-coactivator, however, it unclear which core transcription factor regulates CLCN3.The role of CLCN3 in lung adenocarcinoma (LUAD) unexplored and the relationship between tumor microenvironment unknown.Methods: A 5′-biotin-labeled promoter probe was used to pull down promoter-binding factor.Further study investigated using LUAD samples, cell lines, xenograft mice models, mechanism explored.Results: upregulated human LUAD,...
This paper aimed to study vehicle license locating. It proposed a new algorithm of locating based on color segmentation. In order make the plate more easily analysis and deal with computer, we image enhancement in pretreatment stage. positioning stage, location that utilization information shape. Comparative experiments show segmentation is much accurate speed faster than gray-scale
Abstract Hyperglycemia is prevalent and closely associated with pulmonary tuberculosis (PTB). This study aimed to investigate the effects of hyperglycemia on outcomes PTB treatment. comprised 791 patients in total. Patients fasting plasma glucose levels ≥ 6.1 mmol/L were diagnosed hyperglycemia. Anthropometric baseline demographic data also collected. The treatment response was assessed based clinical symptoms (sputum production, cough, chest pain, fever, hemoptysis, night sweats, loss...
The aim is to investigate the association between nutritional status and clinical picture of pulmonary tuberculosis (PTB).A total 613 patients in Weifang city, Shandong province, China were included. Clinical history, anthropometry, nutritionally relevant indicators including serum protein albumin, hemoglobin lymphocyte count measured. Adjustments made for confounders multivariable logistic models where activity (clinical symptoms signs, sputum-smear tests or chest computerized tomography...
Scope Probiotics are promising in mitigating drug‐induced liver injury animal experiments. However, the clinical evidence is absent. The objective to investigate effect of adjunctive Lactobacillus casei on tuberculosis‐drug‐induced injury. Methods and results A post hoc analysis conducted for a previous randomized controlled trial. trial registered at Chinese Clinical Trial Registry (No. ChiCTR‐IOR‐17013210). Four hundred twenty nine patients allocated receive standard tuberculosis therapy...
ObjectiveTo describe the lineage-specific transmissibility and epidemiological migration of Mycobacterium tuberculosis in China.MethodsWe curated a large set whole genome sequences from 3204 M. isolates, including thousands newly sequenced genomes, applied series metrics to compare strains between lineages sublineages. The countrywide transmission patterns major were explored.ResultsWe found that lineage 2 (L2) was most prevalent China (85.7%), with sublineage 2.2.1 (80.9%), followed by 4...
Besides the two main histologic types of papillary thyroid carcinoma (PTC), classical PTC (CL-PTC) and follicular variant (FV-PTC), several other variants are described. The encapsulated FV-PTC was recently reclassified as noninvasive neoplasm with papillary-like nuclear features (NIFTP) due to its similarities benign lesions. Specific molecular signatures, however, still unavailable. It is well known that improper DNA repair dysfunctional telomeres may cause telomere-related genome...
Anti-tuberculosis (TB) drugs can induce a series of gastrointestinal adverse events, which seriously affect patients’ quality life and may lead to treatment failure.
Schistosomiasis japonicum can cause different degrees of organ damage and complex human immune pathological reactions, which often invade the intestine liver. The purpose this study was to explore types changes their correlation with some digestive system tumors. Hematoxylin eosin staining performed on diseased tissues 1111 cases. We counted deposition sites Schistosoma eggs, analyzed characteristics, compared clinicopathological characteristics associated tumors non-Schistosomiasis found...
Objective: Xeroderma Pigmentosum Complementation Group C (XPC) is a protein involving in nucleotide excision repair (NER). XPC also plays an important role the lung cancer occurrence with mechanism remian unclear up to date. Studies showed that increased stemness of cells related recurrence and metastasis cancer. This study aimed analyze correlation stem cell biomarkers expression overall survival (OS) adenocarcinoma patients. Methods: 140 cases clinical tissue samples 48 paired...
Malnutrition is associated with pulmonary tuberculosis (PTB). The aim of this study to investigate the association between persistent malnutrition and effect PTB treatment.A total 915 patients were included. Baseline demographic information, anthropometry, nutritional indicators measured. treatment was assessed by combinations clinical manifestations, sputum smear, chest computerized tomography, gastrointestinal symptoms, indexes liver function. Persistent considered when one or more lower...
Weaning weight is a key indicator of the early growth performance cattle. An understanding genetic mechanisms underlying weaning will help increase accuracy selection breeding animals. In order to identify candidate genes associated with in Simmental-Holstein crossbred cattle, this study generated RNA-Sequencing (RNA-seq) data from 86 calves (37 males and 49 famales) measured their body size traits (wither height, length, chest girth, rump width, length). Differential gene expression...
Epstein‐Barr virus (EBV) is etiologically linked to nasopharyngeal carcinoma, lymphoma, and gastric carcinoma. The aim of this study was assess the association TM2 domain containing 3 (TM2D3) fibroblast growth factor receptor 2 (FGFR2) SNPs rs675436 rs755793 with susceptibility EBV‐associated tumors in Chinese Han population. Genomic DNA 415 patients cancer 99 healthy controls assessed using a MALDI‐TOF mass spectrometer, genotyped EBV‐associated/‐negative (EBVa/nGC), carcinoma (EBVa/nNPC),...
Abstract Epstein-Barr virus oncogenic latent membrane protein 1 (LMP1) has been known to play important roles in nasopharyngeal carcinoma (NPC). LMP1 gene also induced a variety of microRNAs (miRNAs) which bear pivotal regulation mRNAs expression. However, little was about the global change and miRNAs by NPC. In our study, one NPC tissue microarray profile two LMP1-associated expression profiles data were downloaded from Gene Expression Omnibus database. A protein-protein interaction network...