A5074417010- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Atrial Fibrillation Management and Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Medical Imaging Techniques and Applications
- Neurosurgical Procedures and Complications
- Moyamoya disease diagnosis and treatment
- Radiomics and Machine Learning in Medical Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
- Lanthanide and Transition Metal Complexes
- Advanced MRI Techniques and Applications
- Vascular Malformations Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Salivary Gland Tumors Diagnosis and Treatment
- Meningioma and schwannoma management
- Lipoproteins and Cardiovascular Health
- MRI in cancer diagnosis
- Head and Neck Surgical Oncology
- Clinical practice guidelines implementation
- Neurological Complications and Syndromes
Shizuoka City Shimizu Hospital
2015-2025
Nara Medical University
2025
International Rescue System
2022
Shimizu (Japan)
2020
Tochigi Medical Center
2018
National Hospital Organization
2018
National Cancer Center Hospital East
2010-2016
Endovascular therapy (EVT) has been found to reduce functional disability in patients with acute stroke due large-vessel occlusion. However, the extent of ischemic region, measured using Alberta Stroke Program Early Computed Tomography Scores, may limit efficacy EVT.To compare and safety EVT according ASPECTS 3 or less vs 4 5.The Recovery by Salvage for Cerebral Ultra-acute Embolism-Japan Large Ischemic Core Trial (RESCUE-Japan LIMIT) was an open-label randomized clinical trial conducted...
Background and Purpose— Several studies suggested that statins during hospitalization were associated with better disability outcomes in patients acute ischemic stroke, but only 1 small randomized trial is available. Methods— We conducted a multicenter, open-label, controlled strokes 11 hospitals Japan. Patients stroke dyslipidemia randomly received within 24 hours after admission the early group or on seventh day delayed group, 1:1 ratio. Statins administered for 12 weeks. The primary...
For ruptured cerebral aneurysms over 90 years of age, the outcome and safety after endovascular treatment are not well-known. This multicenter retrospective registry enrolled patients with from January 2015 to December 2019 in Japan. We investigated differences between (age ≥ 90) those under age <90). The primary was defined as a modified Rankin scale 0-2 at 30 days. Secondary outcomes were all-cause death returned premorbid Safety incidence ischemic stroke technical complications. Among...
The effectiveness of endovascular therapy for patients aged 90 years and over (≥90 years) is still not well understood. We compared the ≥90 with those 85-89 years, 80-84 <80 using data from Japanese Registry NeuroEndovascular Therapy that enrolled acute large vessel occlusion January 2015 to December 2019. primary outcome was rate return modified Rankin Scale at least premorbid after 30 days. Secondary outcomes were incidences intracranial hemorrhage mortality.Among 13,540 patients, 1,104,...
Early administration of direct oral anticoagulants in patients with acute large vessel occlusion (LVO) and nonvalvular atrial fibrillation (NVAF) is a concern, as endovascular therapy (EVT) became highly utilized. We conducted historical prospective multicenter registry at 38 centers Japan from July 2016 to February 2018. Patients aged ≥ 20 years NVAF LVO or stenosis who received apixaban within 14 days onset were included. compared < 48 h (Early group) (Late after terms the primary outcome...
Gas-CT cisternography is a simple and accurate procedure for detection of small acoustic nerve tumors. Review one the largest series in single institution found that 98% studies clearly showed presence or absence The diagnostic pitfalls number which significant errors were made, could have been are discussed. It concluded certain situations appear to call extra caution: (a) when filling defect does not show convex surface, (b) amount cisternal gas marginal, (c) canal small. In such careful...
We reported the main results of Japanese Registry Neuroendovascular Therapy (JR-NET) 4, a nationwide surveillance therapy (NET) in Japan from January 2015 to December 2019. JR-NET 4 registered consecutive patients who underwent NETs by Society (JSNET) -certified specialists. The primary endpoint was functional independence (mRS score 0-2) at 30 days post-NET, with secondary endpoints focusing on technical success and major adverse events within days.A total 63,230 60,354 NET procedures 166...
The concept of "watershed shift"(WS)has been proposed as a cause the ischemic complications following superficial temporal artery-middle cerebral artery(STA-MCA)bypass operation performed for management moyamoya disease. Previous reports have observed that only 1.2-5.7% patients who underwent bypass disease developed infarction secondary to WS phenomenon. To date, phenomenon has not objectively proven on imaging studies. We describe 39-year-old woman presented with right facial palsy and...
Mechanical thrombectomy has become a standard treatment for acute ischemic stroke with large vessel occlusion. In aged patients, it is difficult to guide the catheter via transfemoral approach due tortuosity and aortic elongation. We report our preliminary clinical experience using transbrachial approach. Among 119 patients who underwent from April 2018 December 2019, total of 5 were treated Clinical outcomes retrospectively analyzed. Successful reperfusion was achieved in 4 out cases. There...
Acute mechanical thrombectomy (AMT) in patients with acute ischemic stroke from large vessel occlusion (LVO) is performed without directly identifying the occluded vessels. In this study, we evaluated whether 1.5 T magnetic resonance imaging (MRI) 3D-fast employing steady-state acquisition (FIESTA) could visualize intracranial middle cerebral artery (MCA) and internal carotid (ICA) before AMT.This retrospective study included 21 consecutive who underwent time-of-flight angiography (TOF MRA)...
The term "weekend effect" refers to an increase in the mortality rate for hospitalizations occurring on weekends versus weekdays. In this study, we investigated whether such effect exists patients undergoing mechanical thrombectomy acute ischemic stroke with large vessel occlusion (currently standard treatment condition) at a single center Japan.We surveyed 151 who underwent (75 and 76 were treated during daytime nighttime, respectively) from January 2019 June 2021. items evaluated analysis...
Purpose: We retrospectively examined the results of coil embolization for 28 cerebral tiny aneurysms (<3 mm), 73 small (3–4 mm) and associated complications.
Foramen magnum dural arteriovenous fistula (FM-DAVF) is a subset of craniocervical junction fistulas. We report rare case FM-DAVF with early rebleeding and review the literature. A 50-year-old man experienced 3 episodes intracranial bleeding from vessel malformation in acute stage. identified an FM-DAVF, supplied by multiple feeding arteries (eg, left ascending pharyngeal artery) that drained into straight sinus superior petrosal sinus. The draining vein had venous varices. performed...
年 3 月ドイツ BayerHealthCare 社が開発した Gadobutrol(Gd-BT-DO3A)を有効成分とする非イオン 性 magnetic resonance imaging(MRI)検査用造影剤， ガドビスト静注 1.0 mol/L 注射液が発売された．キ レート安定性の高いマクロ環構造を有することから，
Objective: There are regional disparities in endovascular thrombectomy, and problems with emergency transport systems hospital collaboration when transferring need to be addressed. In this study, the clinical outcomes of thrombectomy for transferred patients were analyzed.
Multiple randomized trials have demonstrated the efficacy of mechanical thrombectomy (MT), but very elderly patients aged ≥90 years were excluded. It remains uncertain whether endovascular therapy is effective for nonagenarians. The objective this study was to investigate effectiveness and safety MT in nonagenarians.Between January 2016 March 2019, acute ischemic stroke ≥80 who underwent at our hospital retrospectively reviewed. Patients with a baseline pre-stroke modified Rankin Scale (mRS)...
It is important to start stroke treatment as early possible for patient prognosis. In particular, thrombolysis with the tissue plasminogen activator (tPA) that can dissolve blood clots effective only when it given within 4.5 hours from symptom onset. Since sometimes difficult patients recognize their symptoms, an detection system needed. a be detected by monitoring heart rate variability (HRV) because affects autonomic nervous system. present work, method was proposed integrating HRV...
The aim of this study was to analyze the reason for variation image quality in upper abdomen CT with use CT-AEC. investigated 3D modulation 16MDCT and LSCT phantom used simulate patient. When there a phase difference, an noise increase around 15% at maximum accepted. It is concluded that major respiratory motion importance respiration control must be recognized.