A5100731688- Smoking Behavior and Cessation
- Health Systems, Economic Evaluations, Quality of Life
- Behavioral Health and Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
- Complementary and Alternative Medicine Studies
- Epigenetics and DNA Methylation
- Estrogen and related hormone effects
- Olfactory and Sensory Function Studies
- Connexins and lens biology
- Venomous Animal Envenomation and Studies
- Obesity, Physical Activity, Diet
- Molecular Biology Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Solid State Laser Technologies
- Eating Disorders and Behaviors
- RNA regulation and disease
- Herbal Medicine Research Studies
- Gene expression and cancer classification
- Inflammatory mediators and NSAID effects
- Child and Adolescent Psychosocial and Emotional Development
- Genetic Associations and Epidemiology
- RNA and protein synthesis mechanisms
- Phytochemistry Medicinal Plant Applications
The University of Texas MD Anderson Cancer Center
2014-2025
Shenyang Center for Disease Control and Prevention
2022-2025
Central Hospital of Zibo
2024
China Academy of Engineering Physics
2023
China-Japan Friendship Hospital
2023
Shenyang Ligong University
2023
Vanderbilt University
2004-2022
Institute of Plasma Physics
2022
Chinese Academy of Engineering
2022
Beihang University
2022
The Chinese population has been aging rapidly and the country's economy experienced exponential growth during past three decades. goal of this study was to estimate changes in prevalence dementia, Alzheimer's disease (AD), vascular dementia (VaD) among elderly individuals analyze differences between urban rural areas.For years 2008 2009, we performed a population-based cross-sectional survey with multistage cluster sampling design. Residents aged 65 older were drawn from 30 (n = 6096) 45...
Abstract G-quadruplex (G4) structures have been predicted in the genomes of many organisms and proven to play regulatory roles diverse cellular activities. However, there is little information on evolutionary history distribution characteristics G4s. Here, whole-genome potential G4s were studied 37 evolutionarily representative species. During evolution, number, length, density generally increased. Immunofluorescence seven species confirmed G4s’ presence pattern. tended cluster chromosomes...
Abstract The vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis and permeability. VEGF overexpression has been associated with advanced stage poor survival several cancers. We evaluated the association functional polymorphisms in gene breast cancer a cohort 1,193 patients who were recruited as part population-based case-control study Shanghai, China from 1996 to 1998 followed for recurrence mortality between March 2000 December 2002. Included three (C−460T,...
Status of health information exchange: a comparison six countriesBackground Health exchange (HIE) is frequently cited as an important objective technology investment because its potential to improve quality, reduce cost, and increase patient satisfaction.In this paper we examine the status practices HIE in countries, drawn from range higher lower income regions.Methods For each countries represented -China, England, India, Scotland, Switzerland, United States -we describe state current...
The authors evaluated the associations of ginseng use as a complementary therapy with survival and quality life (QOL) in cohort 1,455 breast cancer patients who were recruited to Shanghai Breast Cancer Study between August 1996 March 1998 Shanghai, China. Patients followed through December 2002. Information on before diagnosis was collected at baseline recruitment linked survival. Survivors' after obtained follow-up survey correlated QOL same time. Kaplan-Meier method Cox regression models...
We evaluated the generalizability of a single nucleotide polymorphism (SNP), rs2046210 (A/G allele), associated with breast cancer risk that was initially identified at 6q25.1 in genome-wide association study conducted among Chinese women. In pooled analysis more than 31,000 women East-Asian, European, and African ancestry, we found positive for [ORs (95% CI) = 1.30 (1.22-1.38) 1.64 (1.50-1.80) AG AA genotypes, respectively, P trend 1.54 × 10⁻³⁰], Japanese 1.31 (1.13-1.52) 1.37 (1.06-1.76),...
Background The impact of serum matrix metalloproteinases‐9 (MMP‐9) on cognitive impairment after ischemic stroke is unclear. We aimed to investigate the association between MMP‐9 in short‐term acute phase and at 3 months. Methods Results Our study was based a subsample from CATIS (China Antihypertensive Trial Acute Ischemic Stroke); total 558 patients with levels 7 26 participating sites trial were included this analysis. Cognitive severity categorized as severe, mild, or none (Mini‐Mental...
Abstract Background: Telomeres are specialized chromatin structures essential for maintenance of chromosomal integrity and stability. Abnormal alteration telomere length has been linked to several cancers; however, epidemiologic evidence about the association with colorectal cancer risk conflicting. Methods: We conducted a nested case–control study evaluate between using peripheral blood samples collected before diagnosis. The included 441 women incident 549 matched controls. Monochrome...
We used multimodal measurement to evaluate whether (a) nicotine dependence is associated with baseline and postquit negative affect craving, (b) smoking relapse greater craving than abstinence, (c) affect. Treatment-seeking smokers were randomly assigned either a brief behaviorally based smoking-cessation treatment condition or delayed control condition. Participants in the attended four assessment sessions, 4-5 days prequit (baseline), 1-2 postquit, 3-5 10-14 while controls sessions spaced...
Purpose Studies suggest that regular use of metformin may decrease cancer mortality. We investigated the association between diabetes medication and survival. Materials Methods The current study includes 633 breast, 890 colorectal, 824 lung, 543 gastric cases identified from participants two population-based cohort studies in Shanghai. Information on was obtained by linking to electronic medical records. associations (metformin, sulfonylureas, insulin) overall cancer-specific survival were...
Dyschromatosis symmetrica hereditaria (DSH) is an autosomal dominant pigmentary genodermatosis characterized by hyperpigmented and hypopigmented macules of on the extremities caused mutations in ADAR gene(also called DSRAD) encoding for RNA-specific adenosine deaminase. Here we reported clinical molecular findings 6 Chinese multi-generation families 2 sporadic patients with DSH. We found that same mutation could lead to different phenotypes even family did not establish a clear correlation...
The most recent advance in laser treatment of benign prostatic hyperplasia (BPH) is the introduction a high-performance system (HPS) 120-W laser. HPS beam at wavelength 532~nm highly absorbed by oxyhemoglobin tissue and ma
The cyclooxygenase 2 (COX-2) pathway is upregulated in many pancreatic cancer cells, and it believed that carcinogenetic effects of COX-2 upregulation are largely through prostaglandin E2 (PGE2) overproduction. We tested this hypothesis by evaluating the association between urinary PGE2 metabolites (PGE-M), a biomarker vivo overproduction, risk. conducted case-control study with 722 subjects (239 cases 483 controls) nested within two prospective cohort studies, Shanghai Women's Health Study...
Studies in Western countries have repeatedly shown that women with a history of childhood sexual abuse (CSA) are at increased risk for developing major depression (MD). Would this relationship be found China?Three levels CSA (non-genital, genital, and intercourse) were assessed by self-report two groups Han Chinese women: 1970 clinically ascertained recurrent MD 2597 matched controls. Diagnostic other factor information was personal interview. Odds ratios (ORs) calculated logistic regression...
Objective To evaluate associations between quality of life (QOL) and use ginseng Ganoderma lucidum (G. lucidum) among breast cancer survivors. Methods Included in this study were 4,149 women with who participated the Shanghai Breast Cancer Survival Study. Ginseng was assessed at 6-, 18-, 36-month post-diagnosis surveys; G. 6- surveys. QOL evaluated Multiple linear regression models used to examine G.lucidum survey, adjustment for potential confounders baseline QOL. Results At 6 months...
Cigarette smoking is thought to be at least partially maintained by the attentional bias (AB) toward cues that develops as a consequence of drug dependence. This study evaluated impact smartphone-delivered, in-home modification (ABM) reduce AB and behavior withdrawal-related symptoms when used an adjunct conventional cessation treatment.Participants (N = 246) were treatment-seeking smokers who completed up 13 days either ABM designed train attention away from cues, using modified dot-probe...
Importance Most people who smoke do not quit on their initial attempt. Objective To determine the best subsequent strategy for nonabstinence following treatment with varenicline or combined nicotine replacement therapy (CNRT). Design, Setting, and Participants Using a double-blind, placebo-controlled, sequential multiple assignment randomized trial, 490 volunteers were to receive 6 weeks of CNRT. After weeks, nonabstainers rerandomized continue, switch, increase medication dosage additional...