A5102879490- Natural product bioactivities and synthesis
- Medicinal Plant Pharmacodynamics Research
- Phytochemical Studies and Bioactivities
- Genomics and Phylogenetic Studies
- Phytochemistry and Bioactive Compounds
- Gut microbiota and health
- Diet and metabolism studies
- Genetic and Kidney Cyst Diseases
- Caveolin-1 and cellular processes
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Pharmacological Effects of Natural Compounds
- Fungal Biology and Applications
- Traditional and Medicinal Uses of Annonaceae
- Dietary Effects on Health
- Helicobacter pylori-related gastroenterology studies
- Metabolism, Diabetes, and Cancer
- Clostridium difficile and Clostridium perfringens research
- Phytochemical compounds biological activities
- Traditional Chinese Medicine Analysis
- Plant tissue culture and regeneration
- Chemical synthesis and alkaloids
- Acute Ischemic Stroke Management
- Chromatography in Natural Products
- Extracellular vesicles in disease
Jiangxi University of Traditional Chinese Medicine
2015-2025
Wuhan University of Science and Technology
2023
Wenzhou Medical University
2014
Importance Trials have not demonstrated superiority of alteplase or tenecteplase vs standard care in patients with mild stroke and raised safety concerns. Prourokinase is an alternative fibrinolytic that may a favorable profile, the benefit-risk profile prourokinase unknown. Objective To investigate efficacy ischemic within 4.5 hours symptom onset. Design, Setting, Participants This was multicenter, prospective, open-label, blinded–end point randomized clinical trial conducted from November...
Obesity, a global health challenge, is characterized by excessive fat accumulation and associated metabolic disorders. The ZhiZhu decoction, traditional Chinese herbal formula consisting of Citrus aurantium L. (ZS, ZhiShi in Chinese) Atractylodes macrocephala Koidz (BZ, Baizhu Chinese), widely recognized clinics for its gastrointestinal regulatory effects. chemical composition ZS-BZ essential oil (ZBEO) was using gas chromatography-mass spectrometry (GC-MS). Concurrently, we conducted vitro...
Roxithromycin (RXM) has been widely used in asthma treatment; however, the mechanism not fully understood. The aim of our study was to investigate underlying RXM treatment mediating effect transforming growth factor (TGF)-β1 on airway smooth muscle cells (ASMCs) proliferation and caveolinn-1 expression.Firstly, rat ovalbumin (OVA) model built according previous papers. Rat ASMCs were prepared cultured, then TGF-β1 production measured by enzyme-linked immunosorbent assay (ELISA). Moreover,...
Sarcandra glabra has significant metabolically active bioingredients of pharmaceutical importance. The deficiency molecular markers for S. is a hindrance in breeding genetic improvement. In this study, 57.756 million pair-end reads were generated by transcriptome sequencing (Thunb.) Nakai and its subspecies ssp. brachystachys. A total 141,954 unigenes with 646.63 bp average length assembled. 25,620 simple sequence repeats, 726,476 single nucleotide polymorphisms, 42,939 insertions deletions...
The Caoguo-4 decoction, a classical Mongolian medicine formula, is widely used to treat spleen deficiency diarrhea (SDD) in for decades. Previously, the decoction volatile oil has been confirmed be effective ameliorating symptoms of an animal model. However, underlying mechanism yet established. aim current study was investigate antidiarrheal effects and oil. Wistar rats were randomly divided into 5 groups 10 animals including control, model, positive, (10 each group). All rats, besides...
Epimedium sagittatum (Sieb. et Zucc.) Maxim. (ESM) which accumulates several principal flavonoid compounds including epimedin A, B, C and icariin, is extensively utilized in traditional herbs for sexual dysfunction, osteoporosis etc. In China, ESM has a wealth of wild plant resources characterized by significant variability medicinal accumulation. Understanding the diversity ESMs can lead to better utilization these resources. this study, we integrated metabolomic transcriptomic analysis...
Abstract Flow-injection mass spectrometry (FIMS) coupled with a chemometric method is proposed in this study to profile and distinguish between rhizomes of Smilax glabra (S. glabra) china china). The employed an electrospray-time-of-flight MS. MS fingerprints were analyzed using principal component analysis (PCA) orthogonal partial least squares discriminant (OPLS-DA) the aid SIMCA software. Findings showed that two kinds samples perfectly fell into their own classes. Further predictive...
Epimedium jinchengshanense Y. J. Zhang & Q. Li 2014 is an important ornamental and medicinal herb, but of unclear taxonomy. In this study, the complete chloroplast genome E. was sequenced. The 157,169 bp in length, with a large single-copy region 88, 520 bp, small 17,075 2 inverted repeat regions 25, 787 bp. consisted 113 unique genes, including 79 protein-coding 30 tRNA genes 4 rRNA genes. GC contents were 38.78%. Phylogenetic analysis showed close relationship between ilicifolium, which...
Both Epimedium sutchuenense Franch. 1894 and E. fargesii are perennial herbs with excellent ornamental values due to their showy flowers. However, little molecular research has been done on these species. Here, the complete chloroplast (cp) genome of was analyzed reported. The cp sizes were 157, 263 133 bp, respectively. two genomes contained a pair inverted repeat regions (IRs) (25,782 25,796 bp), separated by small single-copy (SSC) region (17,106 17,071 bp) large (LSC) (88,593 88,470 bp)....