Fei Ge

ORCID: 0000-0003-4309-7992
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About
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Research Areas
  • Plant Molecular Biology Research
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant tissue culture and regeneration
  • Forest, Soil, and Plant Ecology in China
  • Chromosomal and Genetic Variations
  • Natural product bioactivities and synthesis
  • Phytoestrogen effects and research
  • Genetics and Plant Breeding
  • Cancer and Skin Lesions
  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Plant nutrient uptake and metabolism
  • Image and Signal Denoising Methods
  • Ideological and Political Education
  • Chinese history and philosophy
  • Medicinal Plant Pharmacodynamics Research
  • Genomics and Phylogenetic Studies
  • Cancer, Lipids, and Metabolism
  • Phytochemistry and Biological Activities
  • Ferroptosis and cancer prognosis
  • Genetic and phenotypic traits in livestock
  • Nuts composition and effects
  • Botanical Studies and Applications
  • Dye analysis and toxicity
  • Cancer, Hypoxia, and Metabolism

Jiangxi University of Traditional Chinese Medicine
2005-2024

Kunming Medical University
2018-2024

First Affiliated Hospital of Kunming Medical University
2018-2024

Sichuan Agricultural University
2016-2023

Beijing University of Chinese Medicine
2021

Rutgers, The State University of New Jersey
2018

Guangzhou Panyu Polytechnic
2010

Stalk lodging resistance, which is mainly measured by stem diameter (SD), stalk bending strength (SBS), and rind penetrometer resistance (RPR) in maize, seriously affects the yield quality of maize (Zea mays L.). To dissect its genetic architecture, this study multi-locus genome-wide association studies for resistance-related traits were conducted a population 257 inbred lines, with tropical, subtropical, temperate backgrounds, genotyped 48,193 high-quality single nucleotide polymorphisms....

10.3389/fpls.2018.00611 article EN cc-by Frontiers in Plant Science 2018-05-07

The sprouting of endothelial cells is the first step tumor angiogenesis. Our previous study suggests that miR-153 suppresses breast angiogenesis partially through targeting hypoxia-induced factor (HIF1α). In this study, we demonstrated also migration and tube formation directly angiopoietin 1 (ANG1) in cancer cells. There was a negative correlation between ANG1 levels cancer. blocked expression secretion binding to mRNA. Conditioned medium from cell, MCF7, treated with had no effect on...

10.1007/s10456-018-9630-9 article EN cc-by Angiogenesis 2018-06-29

In this study, a maize inbred line with strong capacity to induce embryonic callus, 18‐ 599R , was used analyze the transcription factors expressed during callus formation. A total of 1180 were found be three key stages induction. Of these, compared control, 361, 346 and 328 significantly downregulated I, II III respectively. contrast, 355, 372 401 ( TFs ) upregulated respective stages. We constructed factor‐mediated regulatory network that plant hormone signal transduction pathway most...

10.1111/ppl.12470 article EN Physiologia Plantarum 2016-05-19

Ferroptosis is a new type of iron-dependent programmed cell death. In recent years, its role in the diagnosis and treatment multiple tumors, including non-small lung cancer (NSCLC), has been continuously observed. The relationship between ferroptosis-related genes prognosis patients with NSCLC needs to be clarified. this study, Cancer Genome Atlas (TCGA) Gene Expression Synthesis database (Gene Omnibus, GEO) were used build model differentially expressed (DEGs). A total 101 DEGs screened...

10.3389/fonc.2022.833814 article EN cc-by Frontiers in Oncology 2022-06-28

Pueraria is a dry root commonly used in Traditional Chinese Medicine or as food and fodder, tuberous expansion an important agronomic characteristic that influences its yield. However, no specific genes regulating have been identified. Therefore, we aimed to explore the mechanism of at six developmental stages (P1-P6), by profiling roots annual local variety "Gange No.1" harvested 105, 135, 165, 195, 225, 255 days after transplanting.Observations phenotype cell microstructural morphology...

10.1186/s12870-023-04303-x article EN cc-by BMC Plant Biology 2023-06-26

Sarcandra glabra has significant metabolically active bioingredients of pharmaceutical importance. The deficiency molecular markers for S. is a hindrance in breeding genetic improvement. In this study, 57.756 million pair-end reads were generated by transcriptome sequencing (Thunb.) Nakai and its subspecies ssp. brachystachys. A total 141,954 unigenes with 646.63 bp average length assembled. 25,620 simple sequence repeats, 726,476 single nucleotide polymorphisms, 42,939 insertions deletions...

10.1155/2021/9990910 article EN cc-by BioMed Research International 2021-07-07

Genetic transformation has been an effective technology to improve agronomic traits of maize, which is highly reliant on the use embryonic callus (EC) and shows a serious genotype-dependence. Herein, we performed genomic sequencing for 80 core maize germplasms constructed high-density variation map using our newly developed pipeline. Based induction rate (REC), these inbred lines were categorized into three subpopulations. The low-REC displayed more abundant genetic diversity than high-REC...

10.1016/j.jia.2023.06.032 article EN cc-by-nc-nd Journal of Integrative Agriculture 2023-06-29

Summary Bulked segregant analysis ( BSA ) is used to identify existing or induced variants that are linked phenotypes. Although it widely in Arabidopsis and rice, remains challenging for crops with large genomes, such as maize. Moreover, of huge data sets can present a bottleneck linking phenotypes their molecular basis, especially geneticists without programming experience. Here, we identified two genes maize defective kernel mutants newly developed pipelines require no programing skills...

10.1111/tpj.14153 article EN The Plant Journal 2018-11-12

The induction efficiency of maize embryonic callus is highly dependent on the genotype, and only a few lines possess high capacity for formation. Although certain genes pathways have been reported to contribute regulation induction, best our knowledge, functions small interfering RNAs (siRNAs) involved in this process remain unknown. In study, we identified 861 differentially expressed siRNAs 576 target process. These were classified into 3 clusters, their involve controlling...

10.1371/journal.pone.0180567 article EN cc-by PLoS ONE 2017-07-03

Abstract Puerariae Thomsonii Radix (PTR) is not only widely used in disease prevention and treatment but also an important raw material as a source of starch other food. The growth years PTR are closely related to its quality. rapid nondestructive identification year essential for the quality control traditional Chinese medicines. In this study, we proposed convolutional neural network (CNN)-based classification framework conjunction with hyperspectral imaging (HSI) technology PTRs....

10.1038/s41598-023-40863-6 article EN cc-by Scientific Reports 2023-08-31

Pueraria is a widely cultivated medicinal and edible homologous plant in Asia, its tuberous roots are commonly used the food, nutraceutical, pharmaceutical industries. "Gange No. 5" local variety of montana var. thomsonii (Bentham) M.R. Almeida (PMT) Jiangxi Province, China. After optimizing cultivation technique, we shortened cycle this from two years to one year, suggesting that regulatory mechanism endogenous hormone system during root expansion may have changed significantly. In study,...

10.1186/s12864-024-11010-w article EN cc-by-nc-nd BMC Genomics 2024-11-19

10.1007/s10600-012-0359-1 article EN Chemistry of Natural Compounds 2012-09-01

Breast cancer is one of the most common malignant tumors affecting women worldwide. a complex disease characterized by abnormal growth cells in breast tissue. Metastasis, spread from primary tumor site to distant organs, major challenge management cancer. Although metastasis sites well-known feature cancer, scalp involvement relatively rare. The occurrence signifies an advanced stage disease. 51-year-old female discovered firm, painless mass her right that had been there for two years. It...

10.2147/ott.s456532 article EN cc-by-nc OncoTargets and Therapy 2024-05-01

Gleditsiae spina (GS) is an important herb used in traditional and folk medicinal systems of East Asian countries for its various properties. In China, it has been traditionally through the centuries anticancer, detoxication, detumescence, apocenosis, antiparasitic effects. Although some ingredients have isolated identified, most active constituents remain unknown. Past research mostly exploited nuclear magnetic resonance identification compounds, which suitable monomers only. Moreover,...

10.1002/rcm.9467 article EN Rapid Communications in Mass Spectrometry 2023-01-03

The ability of immature embryos to induce embryogenic callus (EC) is crucial for genetic transformation in maize, which highly genotype-dependent. To dissect the basis maize EC induction, we conducted QTL mapping four induction-related traits, rate induction (REC), shoot formation (RSF), length (LS), and diameter (DC) under three environments by using an IBM Syn10 DH population derived from a cross B73 Mo17. These traits showed high broad-sense heritability (>80%), significantly negative...

10.3390/ijms23158786 article EN International Journal of Molecular Sciences 2022-08-07

This study explored the relationship between appearance traits and internal components of Cinnamomi Ramulus pieces, so as to provide a reference for quality evaluation formulation grade standards. determined index component contents 41 batches pieces in core producing areas Guangxi Guangdongand established HPLC characteristic map method. The weight narrowest diameter, widest diameter tr ansverse section were used indices traits. content components(cinnamic acid cinnamalde hyde)was by...

10.19540/j.cnki.cjcmm.20240207.301 article EN PubMed 2024-06-01

To explore the mutagenic effect of space environment on Pueraria montana and select elite germplasm with good growth conditions high isoflavone content, this study observed agronomic traits, determined flower labeled amplified fragment length polymorphism(AFLP) fluorescent molecular markers 79 P. plants exposed to mutagenesis(SP1 group) 10 control montana(CK group). Excel 2019, SPSS 25.0, NTSYSpc-2.11F, Popgen 32 were employed analyze genetic diversity perform cluster analysis. The results...

10.19540/j.cnki.cjcmm.20240415.102 article EN PubMed 2024-07-01

Breast cancer (BC) is a malignant tumor, that damages the physical health of female patients. It crucial to develop new treatment strategies for BC, as this disease significantly affects quality life women in both developing and developed countries, despite existence effective options reduce mortality. Recently, several researchers have been studying circular RNAs (circRNAs) BC due their stability sponge function. In present study, circRNA, hsa_circ_0001508, was discovered using Gene Chip's...

10.3892/mco.2024.2808 article EN Molecular and Clinical Oncology 2024-11-28

Epimedium is a widely used medicinal plants. Due to excessive use of wild resources and resource constraints, artificial cultivation the only way achieve sustainable resources. E. pseudowushannense intended first cultivated species, but plant production technology not yet fully mature.The diurnal variation photosynthetic eco-physiological characteristics in different growing age was studied by CI-340 Portable Photosynthesis System under natural conditions. The net rate (Pn), stomatal...

10.4268/cjcmm20161202 article EN China Journal of Chinese Materia Medica 2016-06-15
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