- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Psychosomatic Disorders and Their Treatments
- Cerebral Venous Sinus Thrombosis
- Fetal and Pediatric Neurological Disorders
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Optical Imaging and Spectroscopy Techniques
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Parasite Biology and Host Interactions
- Functional Brain Connectivity Studies
- Neurofibromatosis and Schwannoma Cases
- Parasitic infections in humans and animals
- Health, Environment, Cognitive Aging
- Child Abuse and Related Trauma
- Spinal Fractures and Fixation Techniques
- Cerebrovascular and Carotid Artery Diseases
- Infectious Diseases and Tuberculosis
- Respiratory Support and Mechanisms
- Intestinal Malrotation and Obstruction Disorders
- Trauma Management and Diagnosis
- Intracerebral and Subarachnoid Hemorrhage Research
Steve Biko Hospital
2019-2025
University of Pretoria
2019-2025
Presbyterian Hospital
2024
New York Hospital Queens
2024
Columbia University
2024
NewYork–Presbyterian Hospital
2024
King's College London
2023
South African Medical Research Council
2021
University of Cape Town
2011-2020
SINTEF
2019
Abstract Background Optic nerve sheath diameter (ONSD) is a promising noninvasive parameter for intracranial pressure (ICP) assessment. However, in the setting of aneurysmal subarachnoid hemorrhage (aSAH), several previous studies have reported no association between ultrasonically measured ONSD and ICP. In this study, we evaluate patients with aSAH using novel method automated real-time ultrasonographic measurements explore whether factors such as having undergone surgery affects its to...
Tuberculous meningitis (TBM) is a lethal and commonly occurring form of extra-pulmonary tuberculosis in children, often complicated by hydrocephalus which worsens outcome. Despite high mortality morbidity, little data on the impact neurodevelopment exists. We examined clinical characteristics, neurodevelopmental outcomes TBM hydrocephalus.Demographic (laboratory radiological findings) were prospectively collected children treated for probable definite with hydrocephalus. At 6 months, outcome...
Today, invasive intracranial pressure (ICP) measurement remains the standard, but its invasiveness limits availability. Here, we evaluate a novel ultrasound-based optic nerve sheath parameter called deformability index (DI) and ability to assess ICP noninvasively. Furthermore, ask whether combining DI with diameter (ONSD), more established parameter, results in increased diagnostic ability, as compared using ONSD alone.
Abstract Background Accurate and reliable clinical radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment ICH. The aim this study was investigate functional outcome identify severe disability or death following Materials methods Retrospective population‐based spontaneous Clinical data were obtained from electronic medical records, estimated using the modified Rankin Scale (mRS) before ICH at 3 12 months after Results Four hundred fifty‐two...
Abstract BACKGROUND Measurement of optic nerve sheath diameter (ONSD) is a promising technique for noninvasive assessment intracranial pressure (ICP), but has certain limitations. A recent study showed that the deformability index (DI), dynamic parameter quantifying pulsatile nature sheath, could differentiate between patients with high vs normal ICP. OBJECTIVE To further evaluate diagnostic accuracy DI, when interpreted together ONSD. METHODS This prospective included children undergoing...
Raised intracranial pressure (ICP) may lead to increased stiffness of the optic nerve sheath (ONS).To develop a method for analyzing ONS dynamics from transorbital ultrasound and investigate potential difference between patients with raised ICP vs normal ICP.We retrospectively analyzed data 16 (≤12 years old) whom image sequences had been acquired both eyes just before invasive measurement ICP. Eight an ≥20 mm Hg. The transverse motion on each side was estimated ultrasound, Fourier analysis...
Optic nerve sheath diameter (ONSD) has shown promise as a noninvasive parameter for estimating intracranial pressure (ICP). In this study, we evaluated novel automated method of measuring the ONSD in transorbital ultrasound imaging.From adult traumatic brain injury (TBI) patients with invasive ICP monitoring, bedside manual measurements and videos optic complex were simultaneously acquired. Automatic obtained by processing software based on machine learning approach segmentation sheath....