A5069105349- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Traumatic Brain Injury Research
- Thermal Regulation in Medicine
- Adrenal Hormones and Disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Acute Ischemic Stroke Management
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Anesthesia and Neurotoxicity Research
- Heart Failure Treatment and Management
- Cerebrospinal fluid and hydrocephalus
- Nosocomial Infections in ICU
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Coronary Interventions and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
Research Institute of Emergency Care
2020-2025
State Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A.I. Burnazyan
2016-2025
Federal Medical-Biological Agency
2017-2025
Research Medical Center
2023
Burdenko Neurosurgery Institute
2008-2020
Sechenov University
2020
Ministry of Health of the Russian Federation
2017
Russian Academy of Sciences
2014
After discharge from the Intensive Care Unit (ICU), more than 50 % of patients experience pathological symptoms that are not related to primary emergency but reduce quality life and require rehabilitation. Post Syndrome (PIСS) include only those conditions do have a direct causal relationship with condition gave rise hospitalization in ICU. The pathophysiological basis PICS is phenomenon “learned non-use”: state artificial limitation patient’s motor cognitive activity as result use...
OBJECTIVE . Assessment of patients with impaired consciousness is a priority task in the department intensive care. The Glasgow Coma Scale (GCS), which includes assessment motor , speech and ocular reactions, was first scale developed for this purpose. absence versions GCS that passed validation research, reduces quality its application Russia other Russian-speaking countries limits possibility obtaining objective clinical results during evaluation reduced level wakefulness, significantly...
The optimal hemoglobin (Hb) threshold to trigger red blood cell transfusions (RBCT) in subarachnoid hemorrhage (SAH) patients is unclear. This study evaluated the impact of liberal versus restrictive transfusion strategies on neurological outcome with SAH. a pre-planned secondary analysis "TRansfusion Strategies Acute brain INjured Patients" (TRAIN) study. We included all SAH from original that were randomized receive RBCT when Hb levels dropped below 9 g/dL (liberal group) or 7 (restrictive...
Abstract Background Current practices regarding tracheostomy in patients treated with extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome are unknown. Our objectives were to assess the prevalence and association between timing of (during or after ECMO weaning) related complications, sedative, analgesic use. Methods International, multicenter, retrospective study four large volume centers during a 9-year period. Results Of 1,168 severe ARDS (age 48 ± 16 years,...
During the last two years, treatment of patients with novel coronavirus infection COVID-19 remains an urgent health problem. Interferon proteins are known to play a significant role in antiviral immunity. Some pathological conditions accompanied by production neutralizing autologous immunoglobulins against own host interferons (auto-IFN-Abs). There is evidence that autoantibodies alpha and omega detected life-threatening course pneumonia. The aim our study was analyze prevalence interferon...
COVID-19 pandemic has posed a severe healthcare challenge calling for an integrated approach in determining the clues early non-invasive diagnostics of potentially cases and efficient patient stratification. Here we analyze clinical, laboratory CT scan characteristics associated with high risk COVID-19-related death outcome cohort severely-ill patients Russia. The data obtained reveal that elevated dead lymphocyte counts, decreased apoptotic lymphocytes, CD14+/HLA-Dr+ monocytes, increased...
Extracorporeal membrane oxygenation (ECMO) is increasingly used to treat severe cases of acute respiratory or cardiac failure. Hemorrhagic complications represent one the most common during ECMO, and can be life threatening. The purpose this study was elucidate pathophysiological mechanisms ECMO-associated hemorrhagic their impact on standard viscoelastic coagulation tests. cohort included 27 patients treated with VV-ECMO VA-ECMO. Hemostasis evaluated using tests parameters investigated...
Chronic disorders of consciousness (DOC) represent severe central nervous system damage resulting in long-term disability and a significant burden to healthcare institutions patientsʼ families. DOC develop patients after coma are characterized by the presence wakefulness with complete or almost absence signs awareness. include vegetative state (VS) minimally conscious (MCS). The term prolonged (pDOC) is also used Russian literature describe initial stages chronic DOC. Another clinical...
INTRODUCTION: The development of clinical and methodological recommendations improves the quality medical care reduces risk complications. OBJECTIVE: To analyze “Perioperative management patients with coronary heart disease”, concomitant pathology valvular apparatus” morbid obesity” using modified Delphi method. MATERIALS AND METHODS: A method was used two rounds questionnaires to develop a consensus. agreement specialists reached in three stages: preparatory stage, discussion stage...
Assessment of the individual level consciousness on admission a patient with brain injury to intensive care unit (ICU) is priority task and mandatory step in overall assessment neurological status. The Full Outline UnResponsiveness (FOUR) scale, developed at Mayo Clinic (USA) 2005, widely used tool for comprehensive patients altered state consciousness. lack validated Russian-language version FOUR scale has hindered its widespread use clinical practice. Therefore, official Russian was...
Nosocomial CNS infection (NI-CNS) is a common and serious complication in neurocritical care patients. Timely, accurate diagnosis of NI-CNS crucial, yet current markers lack specificity and/or sensitivity. Presepsin (PSP) novel biomarker macrophage activation. Its utility has not been explored. We first determined the normal range cerebrospinal fluid (CSF) PSP control group without brain injury before collecting data on CSF levels Samples were analyzed four groups defined by systemic...
The aim of the stud y is to evaluate efficacy hyperbaric oxygen therapy and its effect on oxidative stress apoptosis in patients with new coronavirus infection COVID-19. Materials methods . 90 diagnosed caused by SARS-CoV-2 virus were examined. Hyperbaric sessions conducted 57 (38 severe condition (CT 3-4), 19 moderate 1-2)). procedures performed 1.4-1.6 ATA mode for 40 minutes, 247 total performed. oxygenation was assessed measuring level saturation, severity blood lymphocytes. Results In...
Страница 14 ВОЗМОЖНОСТИ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ В ОЦЕНКЕ СТЕПЕНИ ПОРАЖЕНИЯ ЛЕГКИХ У БОЛЬНЫХ COVID-19 УСЛОВИЯХ ДИНАМИЧЕСКОГО НАБЛЮДЕНИЯ Петриков С.С. 1,2, Попова И
The objective of the study: to compare degree lung damage according chest CT data clinical state COVID-19 patient, analyze semiotics and changes in data. Subjects methods. 317 scans were retrospectively analyzed; those belonged 98 patients with treated at N.V. Sklifosovsky Research Institute for Emergency Medicine. Patients divided into 4 groups, depending on lungs detected by during primary examination, their was assessed each subsequent scan. To determine relationship between pulmonary...
Data on intra-abdominal hypertension [IAH] and secondary abdominal compartment syndrome [ACS] due to neurological insults are limited.This was a prospective observational study conducted between January 2010 2011 in the ICU [NICU]. Forty-one consecutive patients with sellar region tumors [SRT] were enrolled into study. If conservative therapy ineffective ACS, thoracic epidural anesthesia [EA] performed. Primary endpoint defined as efficacy of treatment EA IAH ACS; endpoint, influence ACS...
The aim of the study was to evaluate effectiveness cefepime/sulbactam in patients with intra-abdominal infection, nosocomial pneumonia (NP) or ventilator-associated (VAP) actual clinical practice. Material and methods. conducted 14 Russian Clinics from October 2019 March 2020. Study design: an open-label, prospective, non-comparative, multicenter, observational study. included who met inclusion/exclusion criteria signed a written informed consent. studied antibiotic: (Maxictam®-AF). primary...
<h3></h3> Актуальная тема сегодняшнего дня — терапия новой коронавирусной инфекции. Важной особенностью пандемии COVID-19 является отсутствие стандартной терапии, применение всех имеющихся средств носит экспериментальный характер. Опыт предшествующих эпидемий вирусных заболеваний дает основания предположить, что использование плазмы выздоровевших будет эффективным при COVID-19. В данной работе представлены результаты анализа первого опыты клинического применения для лечения в стационарах...
Hospital mortality rate is considered one of the convincing criteria to assess efficacy treatment for ST-elevation myocardial infarction (STEMI). Among predictors risk (MR), age over 75 years most significant one. The aim study was comparatively in patients with recurrent STEMI considering hospital regard baseline MR and/or different timeframes period from 2008 2017. We studied 743 admitted at our Institute clinic first group consisted 312 hospitalized 2011; 51 them were old. PCI performed...