A5101447597- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced biosensing and bioanalysis techniques
- Electronic and Structural Properties of Oxides
- RNA Interference and Gene Delivery
- Advanced Fiber Laser Technologies
- Ferroelectric and Piezoelectric Materials
- Photonic and Optical Devices
- Nanoplatforms for cancer theranostics
- Magnetic and transport properties of perovskites and related materials
- Graphene research and applications
- Optical Network Technologies
- 2D Materials and Applications
- Advanced Photonic Communication Systems
- Advanced Condensed Matter Physics
- MicroRNA in disease regulation
- Semiconductor materials and devices
- Extracellular vesicles in disease
- Acoustic Wave Resonator Technologies
- Nanoparticle-Based Drug Delivery
- Molecular Junctions and Nanostructures
- Photorefractive and Nonlinear Optics
- Quantum and electron transport phenomena
- Ultrasonics and Acoustic Wave Propagation
- Cancer-related molecular mechanisms research
Wuhan University
2025
Chengdu University of Traditional Chinese Medicine
2024
East China University of Technology
2024
Nanjing University
2014-2023
Collaborative Innovation Center of Advanced Microstructures
2014-2023
National Laboratory of Solid State Microstructures
2023
Zhejiang Gongshang University
2023
Yangtze University
2023
Fudan University
2022
Xi'an Polytechnic University
2018-2020
Multi-wavelength semiconductor laser arrays (MLAs) have wide applications in wavelength multiplexing division (WDM) networks. In spite of their tremendous potential, adoption the MLA has been hampered by a number issues, particularly precision and fabrication cost. this paper, we report high channel count MLAs which wavelengths each can be determined precisely through low-cost standard μm-level photolithography/holographic lithography reconstruction-equivalent-chirp (REC) technique....
Quantification of trace serum circulate microRNAs is extremely important in clinical diagnosis but remains a great challenge. Herein we developed an ultrasensitive platform for microRNA 141 (miR-141) detection based on silver coated gold nanorods (Au@Ag NRs) etching process accompanied by surface plasmon resonance (SPR) shift. Both SPR absorption and scattering responses were monitored. Combined amplification cascades catalyzed hairpin assembly (CHA) hybridization chain reaction (HCR) with...
Ferroelectric domain wall memories have been proposed as a promising candidate for nonvolatile memories, given their intriguing advantages including low energy consumption and high-density integration. Perovskite oxides possess superior ferroelectric prosperities but perovskite-based memory integrated on silicon has rarely reported due to the technical challenges in sample preparation. Here, we demonstrate prototype utilizing freestanding BaTiO3 membranes transferred onto silicon. While...
In situ detection and monitoring of telomerase is great importance as it a relatively specific cancer target. However, the complexity biological system makes difficult for nanoprobe to keep absolutely stable have low background in living cells. This study designs probe termed Förster resonance energy transfer (FRET) nanoflare achieve ratiometric fluorescent intracellular with higher specificity, which can effectively resist disturbance from DNase I GSH, etc. The composed gold nanoparticle...
A detailed theoretical analysis of the lasing wavelength precision DFB laser array based on a reconstruction-equivalent-chirp (REC) technique is presented. Experimental results eight-wavelength with equivalent π phase shift (π-EPS) and four-wavelength three shifts are also given. High was obtained. This paper demonstrates that REC promising way for fabricating multiwavelength low cost high yield.
We construct a tumor redox microenvironment responsive core–shell therapeutic nanoagent for multi-mode imaging guided synergistic therapy <italic>in vitro</italic> and vivo</italic>.
We report the epitaxial growth of Ruddlesden-Popper nickelates, $ \mathrm{La}_{n+1}\mathrm{Ni}_{n}\mathrm{O}_{3n+1} $, with n up to 5 by reactive molecular beam epitaxy (MBE). X-ray diffractions indicate high crystalline quality these films and transport measurements show strong dependence on values. Angle-resolved photoemission spectroscopy (ARPES) reveals electronic structure \mathrm{La}_{5}\mathrm{Ni}_{4}\mathrm{O}_{13} showing a large hole-like pocket centered around Brillouin zone...
Inspired by strong mechanical stability of "Y"-shaped beams for building construction, we design a new class quasi-one-dimensional graphene nanostructures, namely, tri-wing (TWG) nanoribbons. TWG possesses significantly augmented against torsional and compression forces, also each wing the can retain independent electronic properties constituent As such, tailoring structures, TWGs provide broader property tunability nanoelectronic application. In addition, zigzag-edged is metallic...
A proof-of-concept strategy for a circulating miRNA assay using personal glucose meter (PGM) was proposed.
Abstract The development of nephrotoxicity largely limits the clinical use chemotherapy. MiRNAs are able to target various genes and involved in regulation diverse cellular processes, including cell apoptosis death. Our study showed that miR-181a expression was significantly increased after 5-fluorouracil (5-FU) treatment renal mesangial cells kidney tissue, which associated with decreased baculoviral inhibition protein repeat-containing 6 (BIRC6) apoptotic rate. Enforced enhanced...
Creating oxide interfaces with precise chemical specificity at the atomic layer level is desired for engineering of quantum phases and electronic applications, but highly challenging, owing partially to lack in situ tools monitor composition completeness surface during growth. Here we report observation layer-by-layer inner potential variations by analysing Kikuchi lines epitaxial growth strontium titanate, providing a powerful real-time technique control A model combining effects mean step...
A DNA tetrahedron–hairpin probe with a high recovery efficiency is designed for <italic>in situ</italic> fluorescence imaging of intracellular telomerase activity.
Hepatocellular carcinoma (HCC) is a major health concern with high morbidity and mortality rate worldwide. However, the mechanism underlying hepatocarcinogenesis remains unclear. Forkhead box P2 (FOXP2) has been implicated in various human cancer types. role of FOXP2 HCC unknown. Western blot immunohistochemistry were used to measure expression protein adjacent normal tissues 50 patients. Wound healing transwell assays determine cell invasion ability. We showed that level was significantly...
Here, we report a novel polymeric nanoparticle prepared by the self-assembly of amphiphilic copolymers containing fluorescent naphthalimide (NAPH) and photochromic spiropyran (SP), which possesses reversibly photoswitchable dual-color fluorescence controlled release properties. The were synthesized incorporating NAPH SP into methyl ether poly(ethylene glycol)-poly(β-amino esters) (MPEG-PAE) via quaternization. nanoparticles would change between yellow purple upon UV visible light irradiation...
Abstract Great enhancement in the thermoelectric performance of CuInTe 2 is achieved through stepwise regulation Cu vacancies. Lowering content can effective introduce large number vacancies, which substantiated by positron annihilation measurements. The carrier concentration thereby successfully tuned from 5.5× 10 18 cm −3 to 3.2× 19 . vacancies strongly suppress lattice thermal conductivity due both enhanced phonon scattering and lowered velocity. As a consequence, high zT value exceeding...
Graphene nanostructures are potential building blocks for nanoelectronic and spintronic devices. However, the production of monolayer graphene with well-defined zigzag edges remains a challenge. In this paper, we report patterning on hexagonal boron nitride (h-BN) substrates by an anisotropic etching technique. We found that hydrogen plasma h-BN is highly due to inert ultra-flat nature surface, resulting in edge formation. The as-fabricated zigzag-edged nanoribbons (Z-GNRs) widths below 30...
As the cellular roles of RNA abundance continue to increase, there is an urgent need for corresponding tools elucidate native functions and dynamics, especially those short, low-abundance RNAs in live cells. Fluorescent aptamers provide a useful strategy create tag biosensor devices. Corn, which binds with 3,5-difluoro-4-hydroxybenzylidene-imidazolinone-2-oxime (DFHO), good candidate because its enhanced photostability red-shifted spectrum. Herein, we report first time utilization Corn as...
A novel scheme for the generation of full-duty-cycle triangular pulses based on an optoelectronic oscillator (OEO) is proposed and experimentally demonstrated. The fundamental tone corresponding to repetition rate generated by OEO. Biasing Mach-Zehnder modulator at quadratic point, small-signal gain OEO maximized, while even-order harmonics in optical intensity are suppressed. By properly setting loop, amplitude first-order harmonic nine times that third-order harmonic. After a 90°...
Plasmon rulers (PRs) exploit the potential of plasmon coupling between individual pairs noble metal nanoparticles in biological processes, especially single-molecule detection. Herein, for first time, we report a strategy based on Ag PRs situ monitoring extension process telomerase primer (TSP) activated by single telomerase.
It is a great challenge to design drug delivery system with controlled manner, especially one triggered by an exclusive endogenous disease marker and easily tracked release process. Herein, we developed platform of carbon dots which were connected stem-loop molecular beacon loaded doxorubicin polyethylene glycol modified folic acid. Such enables drugs on demand under the stimuli microRNA-21, turn fluorescence doxorubicin, allows monitor The intracellular experiment indicated that acid could...
Chewing ability has a strong effect on food digestion. However, little is known about the relationship between mastication degree and subsequent gastric emptying. This study was to explore effects of individual chewing (strong weak) in vivo oral processing characteristics vitro dynamic gastrointestinal starch hydrolysis three types rice (japonica rice, indica waxy rice). Results showed that swallowable bolus weak group had larger holes looser microstructure with more small particles, while...