A5101764018- Glioma Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Viral-associated cancers and disorders
- Brain Metastases and Treatment
- Meningioma and schwannoma management
- Parvovirus B19 Infection Studies
- Ferroptosis and cancer prognosis
- Bone fractures and treatments
- Histiocytic Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Cancer, Hypoxia, and Metabolism
- Neurofibromatosis and Schwannoma Cases
- Lung Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- CNS Lymphoma Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Advanced Fiber Laser Technologies
- Neuroblastoma Research and Treatments
- Cancer Mechanisms and Therapy
- Genetics and Neurodevelopmental Disorders
- Helicobacter pylori-related gastroenterology studies
- HER2/EGFR in Cancer Research
- Endometrial and Cervical Cancer Treatments
- Immune cells in cancer
- Lymphoma Diagnosis and Treatment
University of Michigan
2020-2024
Fudan University
2006-2023
Huashan Hospital
2006-2023
Bozhou People's Hospital
2023
Tongji University
2021
Tianjin Hospital
2017
Southern Medical University
2015
Wenzhou Medical University
2014
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2014
Yancheng Third People's Hospital
2013
Background Preoperative mediastinal staging is crucial for the optimal management of clinical stage I non–small cell lung cancer (NSCLC). Purpose To develop a deep learning signature N2 metastasis prediction and prognosis stratification in NSCLC. Materials Methods In this retrospective study conducted from May 2020 to October population with NSCLC, an internal cohort was adopted establish signature. Subsequently, predictive efficacy biologic basis proposed were investigated external cohort....
Forkhead box protein 3 (Foxp3) is known as a specific marker for regulatory T cells which contribute to immunosuppression in tumor microenvironment. However, existing studies regarding clinical significance of Foxp3+ tumor-infiltrating lymphocytes (TILs) glioblastoma (GBM) remained discrepant. In this study, we aimed explore whether subtype TILs correlated with prognosis patients GBM. well CD8+ ones were detected by immunohistochemistry on paraffin-embedded samples from 62 patients. Staining...
BackgroundHalf of muscle-invasive bladder cancer patients will relapse with metastatic disease and molecular tests to predict are needed. TP63 has been proposed as a prognostic biomarker in cancer, but reports associating it clinical outcomes conflicting. Since is expressed multiple isoforms, we hypothesized that these conflicting associations outcome may be explained by distinct opposing effects differential isoform expression.MethodsUsing RNA-Seq data from The Cancer Genome Atlas (TCGA),...
We reviewed the diagnosis and treatment of six patients with CNS Rosai-Dorfman disease (RDD). Lesions were located in cerebral convexity, middle cranial base, parasaggital, petrous orbit, thoracic spine. Preoperatively, all lesions misdiagnosed as meningioma. Histopathology showed a characteristic feature called emperipolesis, where small lymphocytes or plasma cells engulfed histiocyte cytoplasm. Total resection was performed cases, at an average follow-up 15 months, are alive well no...
Rationale: Anti-N-methyl-D-aspartate receptor (NMDAR) is the most common type of autoimmune encephalitis mediated by NMDAR antibodies. The pathological process remains unclear, especially in patients without tumors or infections. Autopsy and biopsy studies have rarely been reported because favorable prognosis. Pathological findings generally demonstrate mild-to-moderate inflammation. This case report presents severe anti-NMDAR a 43-year-old man any identified triggers. this patient showed...
This report describes the clinicopathological findings of a solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) central nervous system in 59‐year‐old man with space‐occupying lesions on both left anterior basicranial and top tail falx cerebri. The showed small quantities solid papillary areas prominent structure, where atypical cells were compactly arranged along fibrovascular core. components nuclear relocalization signal transducer activator transcription 6 protein, very high specificity...
Abstract TRIM29 (Tripartite Motif 29) also known ATDC, is an E3 ubiquitin ligase frequently upregulated in muscle-invasive bladder cancer (MIBC). We have previously shown global overexpression a genetically engineered mouse model (GEMM) sufficient to ` development and progression MIBC. Other studies strongly suggest cytokeratin-5/14 (Krt5+/Krt14+) expressing basal-stem progenitor cells the urothelium are of origin for MIBC mice. therefore hypothesized that Trim29 expression Krt5+ basal...
Primary testicular lymphoma (PTL) accounts for ~1% of all non-Hodgkin's lymphomas and has a marked tendency systemic relapse. The current study presents unique case diffuse large B-cell non-germinal center subtype, with subcutaneous masses as the sole manifestation first relapse central nervous system second Subcutaneous subsequent brain are extremely rare signs PTL dissemination. patient received methotrexate-based combined chemotherapy achieved partial response. This pattern treatment...
This paper reports a case of duodenal ulcer (A1 stage) after general gastroscopy, when the patient left hospital without discomfort, but felt persistent aggravated abdominal pain in about 20 minutes, so admitted to emergency department due perforation showed by CT, and aspirated CO2 air pump under anesthesia operating room four hours later, performed painless endoscopic repair. Then, he released pneumatosis puncture, accepted ten days symptomatic treatment such as anti-infection following...