A5103260370- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Antimicrobial Resistance in Staphylococcus
- Infant Nutrition and Health
- Musculoskeletal Disorders and Rehabilitation
- Bacterial Identification and Susceptibility Testing
- Healthcare Systems and Practices
- COVID-19 and healthcare impacts
- Shoulder and Clavicle Injuries
- Viral Infections and Vectors
- Immunodeficiency and Autoimmune Disorders
- Shoulder Injury and Treatment
- Long-Term Effects of COVID-19
- Pericarditis and Cardiac Tamponade
- Tuberculosis Research and Epidemiology
- Digestive system and related health
- HIV-related health complications and treatments
- Infant Health and Development
- Peripheral Neuropathies and Disorders
- HIV Research and Treatment
- Yersinia bacterium, plague, ectoparasites research
- Neutropenia and Cancer Infections
- Viral Infections and Immunology Research
- Bacterial biofilms and quorum sensing
Centre Hospitalier Universitaire de Besançon
2020-2024
University of Lausanne
2018-2023
University Hospital of Lausanne
2016-2020
Institut de Recherche pour le Développement
2012-2014
Université de Montpellier
2012-2014
Centre Hospitalier Universitaire de Montpellier
2012-2014
Centre National de la Recherche Scientifique
2012
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2012
Hôpital Saint Eloi
2010
Management of relapsing or refractory immune reconstitution inflammatory syndromes (IRISs) despite corticosteroid therapy is yet to be defined. We describe three HIV-infected patients with corticosteroid-dependent and life-threatening paradoxical syndrome for whom thalidomide treatment induced rapid clinical remission permitted complete withdrawal without relapse.
Abstract To determine the distribution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral loads (VL) during phase infection and their correlation with clinical presentation inflammation‐related biomarkers. Nasopharyngeal swabs from 453 adult SARS‐CoV‐2‐infected patients Department Infectious Diseases, Besançon, France, were collected at time admission or consultation for reverse transcriptase polymerase chain reaction (RT‐PCR) analysis. Clinical information concentrations...
Acute viral infections can lead to heart inflammation, including acute myocarditis. We report a rare case of myopericarditis in young immunocompetent adult, context recent Cytomegalovirus (CMV) infection. The clinical presentation was an influenzae-like syndrome, classical for CMV infection, without any chest pain or dyspnea, but systematic exploration showed multiple inflammation-compatible myopericardial images on MNR-scan. diagnosis asymptomatic established. present the MNR-scan findings...
Abstract Background Staphylococcus aureus is both human commensal and an important pathogen, responsible for community-acquired nosocomial infections ranging from superficial wound to invasive infections, such as osteomyelitis, bacteremia endocarditis, pneumonia or toxin shock syndrome with a mortality rate up 40%. S. reveals high genetic polymorphism detecting the genotypes extremely useful manage prevent possible outbreaks understand route of infection. One current expanded typing method...
During testing for Staphylococcus aureus in an intensive care unit France 2011, we found that methicillin-sensitive S. clonal complex 398 was the most frequent clone (29/125, 23.2%). It isolated from patients (5/89, 5.6%), health workers (2/63, 3.2%), and environmental sites (15/864, 1.7%). Results indicate emergence of this a hospital setting.
Abstract The objective of this study was to identify predictive factors mortality in older adults with coronavirus disease 2019 (COVID‐19), including the level clinical frailty by using scale (CFS). We analyzed medical records all patients aged 75 and a confirmed diagnosis COVID‐19 hospitalized our Hospital between March 3 April 25, 2020. Standardized variables were prospectively collected, standardized care provided patients. One hundred eighty‐six included (mean 85.3 ± 5.78 year). cause...
Background: Tenofovir disoproxil fumarate is a prodrug of tenofovir diphosphate that exposes patients to renal toxicity over the long term. alafenamide, new prodrug, now makes it possible reduce toxicity, but at cost an alteration in lipid profile. There currently no recommendation for follow-up profile when switching from alafenamide. Objective: Our study aimed evaluate effects on function and switch consequences patient management. Methods: Demographic, clinical biological data was...
Some patients with unexplained neurological symptoms sought care for presumed Lyme neuroborreliosis (LNB). We aimed to compare patients' characteristics and without LNB.
Summary Invasive aspergillosis ( IA ) is a life‐threatening infection affecting haematological cancer patients with chemotherapy‐induced neutropenia. The diagnosis of often relies on the detection galactomannan GM in serum or bronchoalveolar lavage fluid BAL ). Bi‐weekly screening has been proposed for pre‐emptive therapeutic approach not receiving mold‐active prophylaxis. We have analysed all cases among malignancies and prolonged neutropenia (>14 days) our institution over 10‐year...
We investigated single nucleotide polymorphisms (SNPs) possibly involved in immune reconstitution inflammatory syndrome of chronic disseminated candidiasis (IRIS-CDC) through a candidate gene approach and prospective matched-control study. found that an SNP located interleukin-1B at rs1143627 was significantly associated with the risk developing IRIS-CDC.
Molecular detection of Orthohantavirus puumalaense (PUUV) RNA during the course disease has been studied in blood patients Sweden and Slovenia. The use urine poorly investigated. aims this work were to study PUUV plasma from a cohort France where different lineage circulates assess instead plasma. Matched samples collected daily hospitalized presenting with fever, pain, thrombocytopenia within last 8 days testing positive for IgM IgG against serum at inclusion and/or approximately 1 month...
Objective: The aim of this study is to characterize chest CT findings neutropenic patients with proven/probable invasive pulmonary aspergillosis (IPA). Methods: Hematological cancer admitted our institution (2007–2017) were retrospectively enrolled if the diagnostic criteria IPA during neutropenia met (EORTC/MSG). Galactomannan (GM) was routinely measured in serum and CT-scan performed case recurrent/persistent fever. Bronchoscopy abnormalities. Chest GM dosage analyzed at time suspicion....
Der 37-jährige Patient sucht die Notfallstation wegen eines vor allem tagsüber auftretenden unproduktiven Hustens, subfebriler Temperaturen, Myalgien seit einer Woche und basal thorakal links lokalisierter, atemabhängiger Schmerzen auf.