A5044088752- Immunodeficiency and Autoimmune Disorders
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Lymphoma Diagnosis and Treatment
- Eosinophilic Esophagitis
- Neuroendocrine Tumor Research Advances
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Monoclonal and Polyclonal Antibodies Research
- Abdominal vascular conditions and treatments
- Potassium and Related Disorders
- Gastroesophageal reflux and treatments
- Eosinophilic Disorders and Syndromes
- Intestinal and Peritoneal Adhesions
- Gestational Trophoblastic Disease Studies
- Adenosine and Purinergic Signaling
- Galectins and Cancer Biology
- Sarcoma Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Chronic Lymphocytic Leukemia Research
- Lung Cancer Research Studies
- Biliary and Gastrointestinal Fistulas
- IL-33, ST2, and ILC Pathways
- Genital Health and Disease
Kyushu University
2019-2023
Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
2015-2017
Optimal management of type 1 gastric neuroendocrine tumors (T1-GNETs) remains unknown, with few reports on their long-term prognosis. This study investigated the clinical characteristics and prognosis T1-GNETs.We reviewed medical records patients diagnosed T1-GNET during 1991-2019 at 40 institutions in Japan.Among 172 patients, endoscopic resection (ER), surveillance, surgery were performed 84, 61, 27, respectively, including 77, 2 pT1a-M, pT1b-SM, pT2 tumors, respectively. The median tumor...
Objective T helper (Th) cells play a central role in the pathogenesis of ulcerative colitis (UC). The present study analyzed changes circulating by administration ustekinumab (UST), an interleukin-12/23p40 antibody. Methods CD4 were isolated from peripheral blood at 0 and 8 weeks after UST treatment, we proportion flow cytometry. Clinical information laboratory data obtained 0, 8, 16 weeks. Patients We evaluated 13 patients with UC who received for induction remission between July 2020...
Objective Flares of inflammatory bowel disease (IBD) can occur infrequently after vaccination for coronavirus 2019 (COVID-19), although the details this phenomenon are poorly understood. To clarify possibility an unfavorable response in patients with IBD, we investigated IBD-related symptoms during COVID-19 vaccination.
Ustekinumab (UST), an antibody targeting the p40 subunit of interleukin (IL)-12 and IL-23, is effective in treating Crohn's disease (CD). To clarify mechanism UST, we investigated T-cell differentiation CD patients treated with UST.Twenty-seven active were enrolled this study. Seventeen 10 anti-tumor necrosis factor (TNF)-alpha therapy. The changes proportions subsets after these therapies analyzed by flow cytometry. Comprehensive gene expression colonic mucosa also evaluated.The frequency T...
Acute esophageal mucosal lesions (AEMLs) are categorized into black esophagitis (type B) and non-black NB) on endoscopy. To clarify the distinct pathophysiology, we compared clinical features hematological findings at onset among 17 patients with type B 6 NB esophagitis. In esophagitis, time to endoscopy after was significantly shorter, blood levels of lactate, urea nitrogen, creatinine, glucose were higher than in However, there no significant intergroup differences incidences other...
Gastrointestinal stromal tumor (GIST) is one of the most common types submucosal tumors (SMTs). Because GIST's malignant potential, it crucial to differentiate from other SMTs. The present study aimed identify characteristic endoscopic findings GISTs in small intestine.We reviewed clinicopathological and 38 patients with endoscopically or surgically resected SMTs intestine. were classified into GIST non-GIST groups, compared between 2 groups.Fifteen had 23 Comparison groups revealed that...
The peer review history for this article is available at https://publons.com/publon/10.1002/hon.2816.
A 50-year-old man who had idiopathic epilepsy in his 20s and been taken levetiracetam lamotrigine orally. For recurrence of epileptic seizure, was changed to 200 mg zonisamide. Two weeks later, he fever 38°, vomiting, severe diarrhea. Physical examination showed mild erosions on lip (Fig. 1a) tongue 1b). He did not have other skin lesions. There were no pathogenic bacteria stool culture tests. His laboratory test white blood cells 2850/μL CRP 26.5 mg/dL. Bone marrow hemophagocytic...
Introduction: The proportion of gastroduodenal ulcers caused by drugs is increasing. However, the risk ulcer from other than nonsteroidal anti-inflammatory (NSAIDs) and low-dose aspirin unclear. An association between immunosuppressive has been suggested. We aimed to identify clinical characteristics associated with in post-liver transplant patients. Methods: study investigated 119 patients who underwent esophagogastroduodenoscopy after liver transplantation, 2 were excluded. Clinical...
Objective The risk of developing peptic ulcers and gastrointestinal bleeding is high in patients with chronic kidney disease (CKD). Whether or not transplant patients, who are treated multiple medications, including immunosuppressive drugs, at an increased unclear. Methods In this retrospective study, we compared the clinical endoscopic features gastroduodenal between CKD patients. subjects underwent upper endoscopy January 2015 March 2021. Results Gastroduodenal were observed more...
Ihara, Yutaro MD, PhD1; Kawano, Hiroyuki PhD2; Yada, Shinichiro Nawata, Aya PhD3; Kubo, Chisachi MD3; Kawatoko, MD4; Torisu, Takehiro PhD5 Author Information