A5045770023- Helicobacter pylori-related gastroenterology studies
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Gastroesophageal reflux and treatments
- Gastrointestinal Tumor Research and Treatment
- Diverticular Disease and Complications
- Mycobacterium research and diagnosis
- Pancreatic and Hepatic Oncology Research
- Liver Diseases and Immunity
- Biliary and Gastrointestinal Fistulas
- Abdominal vascular conditions and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Reproductive System and Pregnancy
- Metastasis and carcinoma case studies
- Microscopic Colitis
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Diagnosis and treatment of tuberculosis
- Autoimmune and Inflammatory Disorders Research
- Acute Lymphoblastic Leukemia research
- Immune Response and Inflammation
- Liver Disease and Transplantation
Fujieda Municipal General Hospital
2014-2025
JIMRO (Japan)
2004
Hamamatsu University
2004
Hamamatsu Medical Center
2004
Seirei Hamamatsu General Hospital
2004
Hamamatsu University School of Medicine
1997-2000
Background and Aims: The Ulcerative Colitis Endoscopic Index of Severity (UCEIS) the Mayo endoscopic score (Mayo ES) are used to evaluate ulcerative colitis (UC) severity. This study compared UCEIS ES for evaluating UC severity outcomes in patients undergoing remission induction during routine clinical practice with aim predicting medium- long-term prognosis.
In Japan, the prevalence of autoimmune gastritis (AIG) is assumed to be very low. With recent rapid decrease in Helicobacter pylori (Hp) prevalence, reports on AIG are increasing. This multicenter registry study aimed clarify characteristics AIG, especially its endoscopic appearance.A total 245 patients with from 11 institutions Japan January 2010 October 2016 were included, and their clinical findings evaluated.Mean age was 67.2 ± 11.4 years, 63.7% participants women. The most common...
The Japanese diagnostic criteria for autoimmune gastritis (AIG) were established by the "Study Group on establishment of type A gastritis," which is related to a workshop associated with Japan Gastroenterological Endoscopy Society (JGES) and Committee AIG Research (CARP). set as follows: cases confirmed diagnosis are patients in whom either endoscopic or histological findings, both, meet requirements who be positive gastric autoantibodies (either anti-parietal cell anti-intrinsic factor...
Gastric adenocarcinoma of fundic-gland type (GA-FG) is a rare variant gastric neoplasia. However, the etiology, classification, and clinicopathological features epithelial neoplasm mucosa lineage (GEN-FGML; generic term GA-FG related neoplasm) are not fully elucidated. We performed large, multicenter, retrospective study to establish new classification clarify GEN-FGML.
BACKGROUND: Little is known about the epidemiology of diverticulitis in Japan. Additional information needed its clinical characteristics and factors associated with complications diverticulitis. OBJECTIVE: This study was designed to determine Japanese patients. DESIGN: a retrospective, multicenter, large-scale, cross-sectional study. SETTINGS: All consecutive patients 21 hospitals final diagnosis acute colonic were included this PATIENTS: A total 1112 patients, including 658 men 454 women,...
OBJECTIVES TNF-α has a major role in inflammatory bowel disease via two receptors, p55 (RI) and p75 (RII) expressed on many cell types, particular neutrophils monocytes (GM). Upon activation of these leukocytes, RI RII are shed into the medium can neutralize TNF. Accordingly, soluble (s-RI/RII) believed to have potent antiinflammatory actions. Further, active UC, GM elevated with behavior recently adsorptive apheresis (GMA) patients severe UC was associated dramatic efficacy. In this study,...
Cytomegalovirus (CMV) is frequently detected in ulcerative colitis (UC) lesions of steroid-refractory patients. This has led to the suspicion that CMV might cause and steroid refractoriness.During 2003 2011, 187 consecutive patients were divided into group I (n = 105), corticosteroid-free thiopurine-free past 6 months, II 82), all corticosteroid refractory. The combination serum immunoglobulin (Ig)M, IgG, antigenemia (Ag), real-time polymerase chain reaction assays performed identify CMV(+)...
Optimal management of type 1 gastric neuroendocrine tumors (T1-GNETs) remains unknown, with few reports on their long-term prognosis. This study investigated the clinical characteristics and prognosis T1-GNETs.We reviewed medical records patients diagnosed T1-GNET during 1991-2019 at 40 institutions in Japan.Among 172 patients, endoscopic resection (ER), surveillance, surgery were performed 84, 61, 27, respectively, including 77, 2 pT1a-M, pT1b-SM, pT2 tumors, respectively. The median tumor...
Abstract Endoscopic submucosal dissection (ESD), the standard treatment for early gastric cancer, typically results in homogeneous flat scars. However, some cases, polypoid nodule scars (PNS) may develop, complicating cancer recurrence assessment. This case report describes a 60‐year‐old man with history of Helicobacter pylori infection who underwent two ESD procedures: first antral and then body adenoma. Subsequently, an erythematous protruding lesion developed at scar site. Lesion biopsy...
Introduction: Recent findings revealed that autoimmune gastritis (AIG) is not rare in Japan. Therefore, the accurate diagnosis of AIG essential upper gastrointestinal practice. Diagnostic criteria for were established 2023; however, conventional fluorescent antibody (FA) method anti-parietal cell titer (APCA) measurements has low accuracy and clinically problematic. Methods: We developed a latex agglutination (LA) using new human-derived antigen. Samples subjected to sera from cases (127...
The aims of the present study were to clarify long-term prognosis endoscopic sphincterotomy (EST) for choledocholithiasis and evaluate need cholecystectomy after EST.Between 1993 2007, 262 patients who underwent successful EST followed up more than 6 months). Eighteen had previously undergone (Group A), 129 a calculous gallbladder (GB) B), 46 GB in situ C), 69 an acalculous D). Late complications, including recurrence choledocholithiasis, acute cholecystitis biliary carcinoma, evaluated.Of...
6-Mercaptopurine (6-MP) is an effective maintenance medication in patients with ulcerative colitis (UC), but toxic effects like myelosuppression limit its clinical benefit. In the blood, 6-thioguanine (6-TGN) formed from 6-MP and mediates therapeutic efficacy most of toxicities 6-MP. The level 6-TGN depends on activity thiopurine methyltransferase (TPMT), inherited as 1 3 polymorphic forms low, moderate, or normal/high activity. Accordingly, dose needs to be pharmacogenetically...
Eosinophilic esophagitis (EoE) is an allergy-associated clinicopathologic condition gaining increasing amount of recognition in various areas the world. While clinical definition and characteristics may differ depending on country region, sufficient studies have not yet been performed Japan.To assess prevalence EoE among Japanese population features associated with disease.Endoscopic data from January 2012 to October 2018 was gathered 9 institutes. EoE, defined as esophageal mucosal...
Ulcerative colitis associated with immune-mediated thrombocytopenia is rare. It has been suggested that antigenic mimicry between platelet surface antigen and bacterial glycoprotein plays a role in this association. We present case which exacerbation of UC sequentially induced development ITP elevation PAIgG. In the case, two episodes occurred, each preceded by UC. After remission UC, remitted PAIgG simultaneously decreased. first episode, onset was about 1 month after However, second much...
This study investigated the trends in idiopathic peptic ulcers, examined characteristics of refractory ulcer, and identified optimal treatment. The 309 patients with ulcer were examined. We allocated ulcers that did not heal after 8 weeks' treatment (6 weeks for duodenal ulcers) to group those healed within this period group. typical risk factors (atherosclerosis-related underlying disease or liver cirrhosis complications) absent 46.6% patients. Absence gastric mucosal atrophy (refractory...