Shanshan Liu

ORCID: 0000-0003-0533-933X
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About
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Research Areas
  • 2D Materials and Applications
  • Topological Materials and Phenomena
  • Graphene research and applications
  • Traditional Chinese Medicine Analysis
  • Electronic and Structural Properties of Oxides
  • Iron-based superconductors research
  • MXene and MAX Phase Materials
  • Magnetic properties of thin films
  • Medical Research and Treatments
  • Cancer Genomics and Diagnostics
  • Multiferroics and related materials
  • Advanced Condensed Matter Physics
  • Cancer Cells and Metastasis
  • Nanoplatforms for cancer theranostics
  • Inflammatory Biomarkers in Disease Prognosis
  • Physics of Superconductivity and Magnetism
  • Pharmacological Effects of Natural Compounds
  • Immunotherapy and Immune Responses
  • Natural Compounds in Disease Treatment
  • Immune cells in cancer
  • Acupuncture Treatment Research Studies
  • Cancer-related molecular mechanisms research
  • Phytochemistry and Biological Activities
  • Flavonoids in Medical Research
  • Perovskite Materials and Applications

Fudan University
2016-2025

State Key Laboratory of Surface Physics
2016-2025

Shanghai University of Traditional Chinese Medicine
2017-2025

First Affiliated Hospital of Fujian Medical University
2025

Affiliated Hospital of Southwest Medical University
2017-2025

Qingdao University
2021-2025

Affiliated Hospital of Qingdao University
2021-2025

Fujian Medical University
2025

Harbin Medical University
2024

Third Affiliated Hospital of Harbin Medical University
2024

Atomically thin 2D layered transition metal dichalcogenides (TMDs) have been extensively studied in recent years because of their appealing electrical and optical properties. Here, the fabrication ReS 2 field‐effect transistors is reported via encapsulation nanosheets a high‐ κ Al O 3 dielectric environment. Low‐temperature transport measurements allow to observe direct metal‐to‐insulator originating from strong electron–electron interactions. Remarkably, photodetectors based on exhibit...

10.1002/adfm.201500969 article EN Advanced Functional Materials 2015-05-22

An advanced visible/infrared dual-band photodetector with high-resolution imaging at room temperature is proposed and demonstrated for intelligent identification based on the 2D GaSe/GaSb vertical heterostructure. It resolves challenges of producing large-scale growth, achieving fast response speed, outstanding detectivity, lower manufacture cost, which are main obstacles industrialization 2D-materials-based photodetection.

10.1002/adma.201604439 article EN Advanced Materials 2017-02-16

Abstract Recently, layered two-dimensional ferromagnetic materials (2D FMs) have attracted a great deal of interest for developing low-dimensional magnetic and spintronic devices. Mechanically exfoliated 2D FMs were discovered to possess ferromagnetism down monolayer. It is therefore importance investigate the distinct properties at low dimensionality. Here, we report wafer-scale growth thin films Fe 3 GeTe 2 via molecular beam epitaxy, their exotic can be manipulated composition interface...

10.1038/s41699-017-0033-3 article EN cc-by npj 2D Materials and Applications 2017-09-04

Electromagnetic (EM) wave pollution is harmful to human health and environment, thus it absolutely important develop new electromagnetic absorbing materials. MAX phases have been attracted more attention as a potential candidate for materials due their high conductivity nanolaminated structure. Herein, two magnetic with multiprincipal elements ((Ti

10.1002/advs.202206877 article EN cc-by Advanced Science 2023-02-02

Vertically stacking two-dimensional (2D) materials can enable the design of novel electronic and optoelectronic devices realize complex functionality. However, fabrication such artificial heterostructures on a wafer scale with an atomically sharp interface poses unprecedented challenge. Here, we demonstrate convenient controllable approach for production wafer-scale 2D GaSe thin films by molecular beam epitaxy. In situ reflection high-energy electron diffraction oscillations Raman...

10.1021/acs.nanolett.5b01058 article EN Nano Letters 2015-04-29

Abstract Owing to the coupling between open Fermi arcs on opposite surfaces, topological Dirac semimetals exhibit a new type of cyclotron orbit in surface states known as Weyl orbit. Here, by lowering carrier density Cd 3 As 2 nanoplates, we observe crossover from multiple-frequency single-frequency Shubnikov–de Haas (SdH) oscillations when subjected out-of-plane magnetic field, indicating dominant role transport. With increase SdH further develop into quantum Hall state with non-vanishing...

10.1038/s41467-017-01438-y article EN cc-by Nature Communications 2017-10-27

Abstract The failure of immunotherapies in immune-excluded tumor (IET) is largely ascribed to the void intratumoral cytotoxic T cells (CTLs). major obstacles are excessive stroma, defective vasculatures and deficiency signals recruiting CTLs. Here we report a dual-mechanism based CTLs infiltration enhancer, Nano-sapper, which can simultaneously reduce physical microenvironment potentiate immunotherapy IET. Nano-sapper consists core that co-loaded with antifibrotic phosphates-modified...

10.1038/s41467-020-14425-7 article EN cc-by Nature Communications 2020-01-30

The rise of two-dimensional (2D) crystalline superconductors has opened a new frontier investigating unconventional quantum phenomena in low dimensions. However, despite the enormous advances achieved towards understanding underlying physics, practical device applications like sensors and detectors using 2D are still lacking. Here, we demonstrate nonreciprocal antenna devices based on atomically thin NbSe2. Reversible charge transport is unveiled NbSe2 through multi-reversal antisymmetric...

10.1038/s41467-020-19459-5 article EN cc-by Nature Communications 2020-11-06

The recent discovery of intrinsic ferromagnetism in two-dimensional (2D) van der Waals (vdW) crystals has opened up a new arena for spintronics, raising an opportunity achieving tunable 2D vdW magnetism. Here, we show that the magnetization and magnetic anisotropy energy (MAE) few-layered ${\mathrm{Fe}}_{3}{\mathrm{GeTe}}_{2}$ (FGT) is strongly modulated by femtosecond laser pulse. Upon increasing excitation intensity, saturation increases approximately linear way coercivity determined MAE...

10.1103/physrevlett.125.267205 article EN Physical Review Letters 2020-12-31

Superconductor-ferromagnet (S-F) interfaces in two-dimensional (2D) heterostructures present a unique opportunity to study the interplay between superconductivity and ferromagnetism. The realization of such nanoscale van der Waals (vdW) crystals remains largely unexplored due challenge making an atomically-sharp interface from their layered structures. Here, we build vdW ferromagnetic Josephson junction (JJ) by inserting few-layer insulator Cr2Ge2Te6 into two layers superconductor NbSe2....

10.1038/s41467-021-26946-w article EN cc-by Nature Communications 2021-11-12

Abstract Background Phosphoinositide 3-kinases (PI3Ks) are critical regulators of diverse cellular functions and have emerged as promising targets in cancer therapy. Despite significant progress, existing PI3K inhibitors encounter various challenges such suboptimal bioavailability, potential off-target effects, restricted therapeutic indices, cancer-acquired resistance. Hence, novel that overcome some these needed. Here, we describe the characterization KTC1101, a pan-PI3K inhibitor...

10.1186/s12943-024-01978-0 article EN cc-by Molecular Cancer 2024-03-14

Cd3As2 is a three-dimensional Dirac semimetal with separated points in momentum space. In spite of extensive transport and spectroscopic studies on its exotic properties, the evidence superconductivity surface states remains elusive. Here, we report observation proximity-induced Nb/Cd3As2 hybrid structures. Our four-terminal measurement identifies pronounced pairing gap (gap size comparable to Nb) surfaces, which exhibits flat conductance plateau differential spectra, consistent our...

10.1038/s41467-019-10233-w article EN cc-by Nature Communications 2019-05-17

Pancreatic ductal adenocarcinoma (PDAC) strongly resists standard therapies since KRAS-mutated cancer cells harbor endogenous resistance toward chemotherapy-induced apoptosis and tumor-associated macrophages (TAMs) activate stroma to create the nearly impenetrable matrix. Herein, we developed a tailored nanocomplex through self-assembly of synthetic 4-(phosphonooxy)phenyl-2,4-dinitrobenzenesulfonate Fe3+ followed by hyaluronic acid decoration, realizing chemodynamic therapy (CDT) combat...

10.1021/acs.nanolett.0c02622 article EN Nano Letters 2020-08-18

Metastasis is the major cause of high mortality in cancer patients; thus, blocking metastatic process critical importance for treatments. The premetastatic niche, a specialized microenvironment with aberrant changes related to inflammation, allows colonization circulating tumor cells (CTCs) and serves as potential target metastasis prevention. However, little effort has been dedicated developing nanomedicine amend niche. Here this study reports niche-targeting micelle modulation...

10.1021/acs.nanolett.9b00495 article EN Nano Letters 2019-04-26

Abstract Failure of conventional clinical therapies such as tumor resection and chemotherapy are mainly due to the ineffective control metastasis. Metastasis consists three steps: (i) cells extravasate from primary sites into circulation system via epithelial-mesenchymal transition (EMT), (ii) circulating (CTCs) form “micro-thrombi” with platelets evade immune surveillance in circulation, (iii) CTCs colonize pre-metastatic niche. Here, we design a systemic metastasis-targeted nanotherapeutic...

10.1038/s41467-021-23466-5 article EN cc-by Nature Communications 2021-05-27

High level of detrimental factors including reactive oxygen species (ROS) and inflammatory cytokines accumulated in the infarct core their erosion to salvageable penumbra are key pathological cascades ischemia-reperfusion injury stroke. Few neuroprotectants can remodel hostile microenvironment for failure interfere with dead or biofunctionally inactive dying cells. Even is temporarily attenuated by medications; insults from still erode continuously along drug metabolism clearance. Herein, a...

10.1021/acsami.2c09020 article EN ACS Applied Materials & Interfaces 2022-06-13

The anomalous Hall effect (AHE) is a key transport signature revealing the topological properties of magnetic compounds. In quantum materials, classical linear dependence AHE on magnetization often breaks down, which typically ascribed to presence or electronic textures. However, complex structure these compounds may offer alternative, unexplored mechanisms. Here, we show that giant nonlinear can originate from series magnetic-field-induced Lifshitz transitions in spin-dependent band...

10.1103/physrevresearch.4.023100 article EN cc-by Physical Review Research 2022-05-06

Two dimensional (2D) alloys, especially transition metal dichalcogenides, have attracted intense attention owing to their band-gap tunability and potential optoelectrical applications. Here, we report the controllable synthesis of wafer-scale, few-layer GaTexSe1–x alloys (0 ≤ x 1) by molecular beam epitaxy (MBE). We achieve a layer-by-layer growth mode with uniform distribution Ga, Te, Se elements across 2 in. wafers. Raman spectroscopy was carried out explore composition-dependent vibration...

10.1021/acsnano.5b03796 article EN ACS Nano 2015-08-02

Mechanically exfoliated two-dimensional ferromagnetic materials (2D FMs) possess long-range order and topologically nontrivial skyrmions in few layers. However, because of the dimensionality effect, such few-layer systems usually exhibit much lower Curie temperature (T C) compared to their bulk counterparts. It is therefore great interest explore effective approaches enhance T C, particularly wafer-scale for practical applications. Here, we report an interfacial proximity-induced high-T C 2D...

10.1093/nsr/nwz205 article EN cc-by National Science Review 2019-12-13
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