- Asthma and respiratory diseases
- Mast cells and histamine
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Bacterial Identification and Susceptibility Testing
- Congenital Anomalies and Fetal Surgery
- Biosensors and Analytical Detection
- Dermatology and Skin Diseases
- Surgical site infection prevention
- Food Allergy and Anaphylaxis Research
- Antibiotic Resistance in Bacteria
- Clinical practice guidelines implementation
- Hepatitis B Virus Studies
- Biotin and Related Studies
- COVID-19 Clinical Research Studies
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Toxoplasma gondii Research Studies
- Olfactory and Sensory Function Studies
Second Affiliated Hospital of Xi'an Jiaotong University
2020-2025
Ningxia Medical University
2021-2025
Ningxia Medical University General Hospital
2024-2025
Yixing People's Hospital
2025
Jiangsu University
2025
Xuzhou Medical College
2024
The First People’s Hospital of Lianyungang
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Second Hospital of Shandong University
2023
Fu Wai Hospital
2023
Most persons infected with SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), develop virus-specific antibodies within several weeks, but antibody titers might decline over time. Understanding timeline of is important for interpreting SARS-CoV-2 serology results. Serum specimens were collected from a convenience sample frontline health care personnel at 13 hospitals and tested to during April 3-June 19, 2020, again approximately 60 days later assess this timeline. The...
To analyse the antibiotic resistance, resistance genes and clonal relationship of Escherichia coli in bloodstream infections Ningxia from 2022 to 2023. We retrospectively analyzed susceptibilities 257 isolates. PCR was used detect blaTEM, blaSHV, blaCTX−M, qnrS, qnrA, qnrB, oqxA, qepA, gyrA, gyrB, parC, parE, through multilocus sequence typing (MLST). One hundred twenty-nine patients were male (50.2%). The E. isolates mainly obtained Emergency, Hepatobiliary Surgery, Haematology Departments,...
Nephrotic syndrome (NS) is a common disorder in children that significantly affects their health. Children with NS often suffer from urinary tract infections (UTIs), which are complications not only complicate treatment but also worsen prognosis. The aim of this study was to analyze the factors associated UTIs and investigate potential intervention strategies. Ninety-four pediatric patients who were admitted our hospital January 2023 October selected. Among these patients, 34 included...
To elucidate the molecular epidemiology of tigecycline and carbapenem-resistant Enterobacteriaceae isolates mechanisms resistance. We gathered 31 unduplicated strains tigecycline-resistant from six hospitals nationwide. Antimicrobial susceptibility testing, phenotypic detection, PCR identification were performed first, followed by homology analysis using MLST PFGE. Conjugation transfer experiments resistance gene plasmids carried out, conjugates' growth curves examined. All sequenced...
Adaptive immune response has been thought to play a key role in SARS-CoV-2 infection. The of B cells, CD4
We present a face recognition method based on sparse representation for recognizing 3D meshes under expressions using low-level geometric features.First, to enable the application of framework, we develop uniform remeshing scheme establish consistent sampling pattern across faces.To handle facial expressions, design feature pooling and ranking collect various types features rank them according their sensitivities expressions.By simply applying framework collected features, our proposed...
Cystic echinococcosis (CE) is a zoonotic parasitic disease spread worldwide caused by Echinococcus granulosus ( E g), which sometimes causes serious damage; however, in many cases, people are not aware that they infected. A number of recombinant vaccines based on g used to evaluate their effectiveness against the infection. Our previous report showed g.P29 (r g.P29) has marvelous immunoprotection and can induce Th1 immune response. Furthermore, data miRNA microarray mice spleen CD4 + T cells...
Cystic echinococcosis (CE) is a parasitic disease that caused by Echinococcus granulosus (Eg). The recombinant antigen P29 (rEg.P29) was shown to confer effective immunity sheep and mice during E. secondary infection in our previous study. In this study, we sought investigate the ability of long noncoding RNA 028466 (lncRNA028466) as regulator for protective mediated rEg.P29 vaccination study effects lncRNA028466 on CD4+T cell differentiation spleen.Female BALB/c were divided into two groups...
Abstract Cold atmospheric plasma (CAP) has attracted increasing attention due to its anti‐bacterial and anti‐tumor effects. Melanoma is an aggressive malignancy with incidence rate poor prognosis. Evaluating cell viability, apoptosis reactive species injection efficiency of melanoma cells human keratinocyte (HaCaT) treated CAP analyze biological safety CAP. RNA‐sequencing (RNA‐seq) A875 before after treatment was performed further explore the mechanism had a more significant effect on than...
Sheep are an important livestock species worldwide and essential large-animal model for animal husbandry veterinary research. Understanding fundamental immune indicators, especially T-lymphocyte parameters, is necessary research on sheep diseases vaccines, to better understand the response bacteria viruses reducing use of antibiotics improving welfare sheep. We randomly selected 36 similar ages analyze cell-related indicators in peripheral blood mononuclear cells (PBMCs). The proportions...
Cystic echinococcosis (CE) is a neglected parasitic zoonotic disease caused by the larval stage of tapeworm Echinococcus granulosus (E. granulosus). This study aimed to understand clinical characteristics human CE in Ningxia Hui Autonomous Region (NHAR) located northwest China and investigate antibody profiles against recombinant E. antigen P29 (rEg.P29) plasma patients.A total 37 patients, along with healthy donors enrolled this demographic data were analyzed, including age, gender,...
Purpose: To understand the detection rate and distribution characteristics of Linezolid-nonsusceptible Enterococcus (LNSE) analyze molecular typing main drug resistance mechanisms LNSE, providing a theoretical basis for precision prevention control LNSE hospital infections. Methods: A total 40 strains isolated from clinical specimens between January 1, 2012, December 31, 2022, were collected. The isolates identified by instrument confirmed using microbroth dilution method. WHONET 5.0...
Abstract Introduction Echinococcus granulosus ( E . ) causes a hazardous zoonotic parasitic disease. This parasite can occupy the liver and several areas of body, causing incurable damage. Our previous studies have provided evidence that recombinant protein P29 rEg.P29 exhibit immune protection in sheep mice against pathological damage induced by E. , showing its potential as candidate for vaccine development. However, information on B‐cell epitopes has not yet been reported. Methods...
Hydroquinone (HQ) is one of the most effective drugs to treat hyperpigmentary disorders, but often causes skin irritation in clinic. Mast cell plays an important role contact dermatitis and triggering pseudo-allergic reactions via MRGPRX2. Whether HQ-induced irritant reaction through activating mast cells MRGPRX2 remains unknown. To investigate verify whether participated HQ effect on which contributed pathogenesis reaction, a mouse model was established observe local systemic inflammation...
This study aimed to analyze the clinical features, antibiotic susceptibility profiles, and outcomes of patients with invasive pneumococcal disease (IPD) at a hospital in Ningxia Hui Autonomous Region, provide basis for improving treatment effect.Patients IPD were retrospectively collected from 2013 2021. Clinical manifestations, laboratory tests, antimicrobial susceptibility, treatment, analyzed.In this study, we identified 127 cases, whom 49 (38.6%) had meningitis 78 (61.4%) bacteremia. The...