A5032209159- Glioma Diagnosis and Treatment
- Autoimmune Neurological Disorders and Treatments
- Brain Metastases and Treatment
- Peripheral Neuropathies and Disorders
- Neurology and Historical Studies
- Myasthenia Gravis and Thymoma
- Cancer Treatment and Pharmacology
- Peripheral Nerve Disorders
- Meningioma and schwannoma management
- Nerve Injury and Rehabilitation
- CNS Lymphoma Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Hereditary Neurological Disorders
- Botulinum Toxin and Related Neurological Disorders
- Orthopedic Surgery and Rehabilitation
- Management of metastatic bone disease
- Palliative Care and End-of-Life Issues
- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Pharmacological Effects and Toxicity Studies
- Parkinson's Disease and Spinal Disorders
- Epilepsy research and treatment
- Neurological Complications and Syndromes
- Multiple Myeloma Research and Treatments
- Neurogenetic and Muscular Disorders Research
Ludwig Boltzmann Institute for Experimental and Clinical Traumatology
2016-2025
University of Vienna
1981-2025
Medical University of Vienna
1984-2024
World Federation for Mental Health
2017-2022
Maastricht University
2021
Johns Hopkins University
2021
University of Milano-Bicocca
2012-2021
Mohammed V University
2021
University of Siena
2021
Ludwig Boltzmann Institute for Digital Health and Prevention
2006-2020
The entopeduncular nucleus (EPN) and substantia nigra pars reticulata (SNr) constitute the output nuclei of basal ganglia, but studies on EPN are limited compared with those SNr. Both receive projections from striatum axons containing substance P (SP) cannabinoid type-1 receptor (CB1R), immunoreactivities for these substances show complementary patterns in In this study we revealed a similar complementarity mouse EPN, combined it region-specific neuronal distributions, defined subregions...
Anaplastic oligodendroglioma are chemotherapy-sensitive tumors. We now present the long-term follow-up findings of a randomized phase III study on addition six cycles procarbazine, lomustine, and vincristine (PCV) chemotherapy to radiotherapy (RT).Adult patients with newly diagnosed anaplastic oligodendroglial tumors were randomly assigned either 59.4 Gy RT or same followed by adjuvant PCV. An exploratory analysis correlation between 1p/19q status survival was part study. Retrospectively,...
Anaplastic oligodendrogliomas are more responsive to chemotherapy than high-grade astrocytomas. We investigated, in a multicenter randomized controlled trial, whether adjuvant procarbazine, lomustine, and vincristine (PCV) improves overall survival (OS) newly diagnosed patients with anaplastic or oligoastrocytomas.The primary end point of the study was OS; secondary points were progression-free (PFS) toxicity. Patients randomly assigned either 59.4 Gy radiotherapy (RT) 33 fractions only same...
Background: Diffuse infiltrative low‐grade gliomas of the cerebral hemispheres in adult are a group tumors with distinct clinical, histological and molecular characteristics, there still controversies management. Methods: The scientific evidence papers collected from literature was evaluated graded according to EFNS guidelines, recommendations were given accordingly. Results conclusions: WHO classification recognizes grade II astrocytomas, oligodendrogliomas oligoastrocytomas. Conventional...
Background: Paraneoplastic neurological syndromes (PNS) almost invariably predate detection of the malignancy. Screening for tumours is important in PNS as tumour directly affects prognosis and treatment should be performed soon possible. Objectives: An overview screening related to classical given. Small cell lung cancer, thymoma, breast ovarian carcinoma teratoma testicular are described relation paraneoplastic limbic encephalitis, subacute sensory neuronopathy, autonomic neuropathy,...
Paraneoplastic neurological syndromes (PNS) are remote effects of cancer on the nervous system. An overview management classical PNS, i.e. paraneoplastic limbic encephalitis, subacute sensory neuronopathy, cerebellar degeneration, opsoclonus-myoclonus, Lambert-Eaton myasthenic syndrome and peripheral nerve hyperexcitability is given. Myasthenia gravis paraproteinemic neuropathies not included in this report. No evidence-based recommendations were possible, but good practice points agreed by...
Background: Data on the incidence of neuropathic pain (NeP) in Austria, its general characteristics and consequences for quality life (QOL) are still lacking. The prevalence United Kingdom is 8%. Methods: A representative survey ( n =7707) was carried out. Patients with NeP were identified using previously validated criteria subsequently asked to complete a questionnaire QOL detailed characteristics. Results: 3.3% =260). higher found 41–50‐year‐olds (26%) 51–60 year olds (24%). Pain long...
The objectives have been to establish evidence-based guidelines and identify controversies regarding the management of patients with brain metastases. collection scientific data was obtained by consulting Cochrane Library, bibliographic databases, overview papers previous from societies organizations. A tissue diagnosis is necessary when primary tumor unknown or aspect on computed tomography/magnetic resonance imaging atypical. Dexamethasone corticosteroid choice for cerebral edema....
Peritumoral brain edema in glioblastoma patients is a frequently encountered phenomenon that strongly contributes to neurological signs and symptoms. The role of peritumoral as prognostic factor controversial.This multi-centre clinical retrospective study included 110 with histologically proven glioblastoma. impact on overall survival pre-treatment detected MRI-scans was evaluated. All had preoperative MRI, surgery, histology, received standard treatment regimens. Edema classified minor (<1...
To define the frequency and clinical immunologic characteristics of patients affected by paraneoplastic neurologic syndromes (PNS) lymphoma.Patients fulfilling criteria for PNS associated with lymphoma collected from European Commission-funded Euronetwork group database were analyzed.Fifty-three Hodgkin (HL) (24 patients, mean age 51, range 16-84) or non-Hodgkin (NHL) (29 64, 31-82) analyzed. The most commonly was cerebellar degeneration, present in 21 cases, a higher prevalence HL (16/24...
A series of patients with anti-Hu-associated brainstem encephalitis is reviewed to better define the clinical presentation and improve its recognition.Data were collected from 14 diagnosed by members Paraneoplastic Neurological Syndromes Euronetwork, eight literature who presented isolated had anti-Hu antibodies.The median age 22 was 64 years (range 42-83), 50% men. All developed a subacute neurological syndrome, in days or weeks. Brain MRI always normal. Mild cerebrospinal fluid pleocytosis...