A5101912285- Plant Virus Research Studies
- Plant Gene Expression Analysis
- RNA and protein synthesis mechanisms
- Seed Germination and Physiology
- Plant tissue culture and regeneration
- Crop Yield and Soil Fertility
- Genetics and Plant Breeding
- Plant Molecular Biology Research
- HIV Research and Treatment
- Phytochemicals and Antioxidant Activities
- Plant biochemistry and biosynthesis
- Bacteriophages and microbial interactions
- Plant and Fungal Interactions Research
- Plant Stress Responses and Tolerance
- HIV/AIDS Research and Interventions
- Plant Disease Resistance and Genetics
- Photosynthetic Processes and Mechanisms
- Mitochondrial Function and Pathology
- Cell death mechanisms and regulation
- Plant-Microbe Interactions and Immunity
- Viral Infections and Immunology Research
- CRISPR and Genetic Engineering
- Cardiac Ischemia and Reperfusion
- Genomics and Phylogenetic Studies
- HIV/AIDS drug development and treatment
GenVec
2025
Gansu Agricultural University
2025
Inner Mongolia University
2010-2024
Southern Medical University
2024
National Clinical Research Center for Digestive Diseases
2024
Northeast Agricultural University
2024
People's Hospital of Xinjiang Uygur Autonomous Region
2024
Yunnan Archaeology
2024
Inner Mongolia Normal University
2024
University of Maryland, College Park
2012-2023
Activation of p38 mitogen-activated protein kinase (MAPK) plays an important role in apoptotic cell death. The MAPK myocardial injury caused by ischemia/reperfusion, extreme stress to the heart, is unknown.Studies were performed with isolated, Langendorff-perfused rabbit hearts. Ischemia alone a moderate but transient increase activity (3.5-fold increase, P<0.05 versus basal). followed reperfusion further activated MAPK, and maximal level activation (6.3-fold, P<0.01) was reached 10 minutes...
Ulcerative colitis (UC) is often accompanied by intestinal inflammation and disruption of epithelial structures, which are closely associated with changes in the microbiota. We previously revealed that Min pigs, a native Chinese breed, more resistant to dextran sulfate sodium (DSS)-induced than commercial Yorkshire pigs. Characterizing microbiota pigs would allow identification core microbes confer resistance. By analyzing linked disease course we observed
Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In yeast S. cerevisiae, DNA microarrays have not only been used to measure mRNA abundance for all genes under a variety of conditions but also determine occupancy promoter regions by large number transcription factors. The challenge is extract useful global network from these data. We present MA-Networker, algorithm that combines microarray data expression and factor define...
2882MetricsTotal Downloads288Last 6 Months58Last 12 Months99Total Citations2Last Months0Last Months0View all metrics
Abstract The mechanisms of viral diseases are a major focus biology. Despite intensive investigations, how plant virus interacts with host factors to cause remains poorly understood. Rice dwarf (RDV), member the genus Phytoreovirus, causes dwarfed growth phenotypes in infected rice (Oryza sativa) plants. outer capsid protein P2 is essential during RDV infection insects and thus influences transmission by insect vector. However, its role within unknown. By yeast two-hybrid...
The development of biomedical interventions to reduce acquisition HIV-1 infection remains a global priority, however their potential effectiveness is challenged by very high envelope diversity. Two large prophylactic trials in incidence, clade C epidemic regions southern Africa are imminent; passive administration the monoclonal antibody VRC01, and active immunization with modified RV144-like vaccines. We have created representative panel viruses enable assessment responses vaccines natural...
Background: In vitro evidence suggests that the p38 mitogen-activated protein kinase (p38 MAPK) plays a crucial role in PMN activation and inflammatory cytokine production. However, effect of MAPK on myocardial reperfusion injury, pathologic condition involving typical response, has not been fully examined. present study, we investigated SB 239063, specific inhibitor, injury murine ischemia/reperfusion (I/R) model elucidated mechanism by which inhibitor may exert its protective against I/R...
Summary Wheat seeds can be released from a dormant state by after‐ripening; however, the underlying molecular mechanisms are still mostly unknown. We previously identified transcriptional programmes involved in regulation of after‐ripening‐mediated seed dormancy decay wheat ( T riticum aestivum L.). Here, we show that maintenance and its release dry after‐ripening is associated with oxidative modification distinct seed‐stored mRNA s mainly correspond to phosphorylation, ribosome biogenesis,...
Salt stress is one of the major abiotic stresses affecting plant growth and productivity. Vacuolar H+-pyrophosphatase (H+-PPase) genes play an important role in salt tolerance multiple species.In this study, promoter from vacuolar Thellungiella halophila (TsVP1) was cloned compared with AVP1 Arabidopsis thaliana. Sequence analysis indicated that these two promoters had seven similar motifs at positions. To determine which tissues are active in, transgenic plants were produced expression GUS...
Many plant RNA viruses contain elements in their 3' untranslated regions (3' UTRs) that enhance translation. The PTE (Panicum mosaic virus-like translational enhancer) of Pea enation virus (PEMV) binds to eukaryotic initiation factor 4E (eIF4E), but how this affects translation from the 5' end is unknown. We have discovered a three-way branched element just upstream PEMV engages long-distance kissing-loop interaction with coding sequence hairpin critical for reporter construct and...
Maintenance and release of seed dormancy is regulated by plant hormones; their levels sensitivity being the critical factors. This study reports transcriptional regulation brassinosteroids (BR), ethylene (ET), cytokinin (CK) salicylic acid (SA) related wheat genes after-ripening, a period dry storage that decays dormancy. Changes in expression hormonal due to after-ripening did not occur anhydrobiotic state but rather hydrated state. After-ripening induced decay appears be associated with...
Clubroot disease is devastating to Brassica crop production when susceptible cultivars are planted in infected fields. European turnips the most resistant sources and their resistance genes have been introduced into other crops such oilseed rape (Brassica napus L.), Chinese cabbage vegetables. The clubroot differential (ECD) set contains four turnip accessions (ECD1 ECD4). These ECD exhibited high levels of they were tested under controlled environmental conditions with Canadian field...
Nonsense-mediated decay (NMD) represents an RNA regulatory pathway that degrades both natural and faulty messenger RNAs with long 3′ untranslated regions. NMD targets diverse families of viruses, requiring viruses counteract the for successful amplification in host cells. A protein required long-distance movement Pea enation mosaic virus 2 (PEMV2) is shown to also protect viral mRNAs from NMD. RNA-seq analyses Nicotiana benthamiana transcriptome revealed PEMV2 infection significantly impairs...
Since plug seedling plays a key role in automatic transplanting, this work aimed to explore the effect biochar has on root growth of seedlings. The physicochemical properties tests showed that addition peats could increase porosity, pH, and EC values substrate, substrates treated with 0%, 10%, 20%, 30% meet requirements raising. water retention substrate was superior proportion, nitrogen release significantly decreased proportion. Our results demonstrated 10% biochar-treated apparently...
We report the biological and structural characterization of umbravirus-like associated RNAs (ulaRNAs), a new category coat-protein dependent subviral RNA replicons that infect plants. These encode an RNA-dependent polymerase (RdRp) following −1 ribosomal frameshift event, are 2.7–4.6 kb in length, related to umbraviruses, unlike similar tombusviruses. Three classes ulaRNAs proposed, with citrus yellow vein virus (CYVaV) placed Class 2. With exception CYVaV, 2 3 additional open reading frame...
ABSTRACT Many plant viruses without 5′caps or 3′ poly(A) tails contain proximal, cap-independent translation enhancers (3′CITEs) that bind to ribosomal subunits factors thought assist in ribosome recruitment. Most 3′CITEs participate a long-distance kissing-loop interaction with 5′ proximal hairpin deliver the end for initiation. Pea Enation Mosaic Virus (PEMV) contains two adjacent center of its 703-nucleotide untranslated region (3′UTR), ribosome-binding, T-shaped structure (kl-TSS) and...
Abstract Programmed -1 ribosomal frameshifting (-1 PRF) is used by many positive-strand RNA viruses for translation of required products. Despite extensive studies, it remains unresolved how cis-elements just downstream the recoding site promote a precise level frameshifting. The Umbravirus Pea enation mosaic virus RNA2 expresses its polymerase PRF 5′-proximal ORF (p33). Three hairpins located in vicinity are phylogenetically conserved among Umbraviruses. central Recoding Stimulatory Element...